Renal dysfunction in Leishmaniasis and Chagas disease coinfection: a case report

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Cid Carlos Soares de Alcântara, Laís Regina Lacerda Santana, Priscila Dourado Evangelista, André Costa Teixeira, Geraldo Bezerra da Silva Junior, Elizabeth De Francesco Daher
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 2018
• Subjects: Leishmaniasis; Acute kidney injury; Glomerulonephritis; Chagas disease; Parasitic diseases; Cardiomyopathy; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/s1678-9946201860073; https://doaj.org/article/9b6dbdc721e743afaa3ec5cfa1afc7a3

ABSTRACT Visceral leishmaniasis (VL) is an endemic parasitic disease frequently found in Northeast Brazil and may cause acute kidney injury (AKI) and glomerulonephritis. After appropriate treatment, renal function recovery may occur. We describe the rare case of a patient with VL, who developed severe AKI requiring dialysis and was subsequently diagnosed with Chagas disease coinfection. After specific treatment for VL, there was partial recovery of the renal function, followed by the onset of Chagas disease cardiomyopathy.