International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas
Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic. Moreover, in most places, neither blood banks nor healthcare units offer diagnostic confirmation or treatment access. By the time pa...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Format: | Article in Journal/Newspaper |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2008
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Online Access: | https://doi.org/10.1590/S0037-86822008000300020 https://doaj.org/article/9b5fdbddffce4147bd33ae845aee2c76 |
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ftdoajarticles:oai:doaj.org/article:9b5fdbddffce4147bd33ae845aee2c76 2023-05-15T15:17:37+02:00 International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas 2008-06-01T00:00:00Z https://doi.org/10.1590/S0037-86822008000300020 https://doaj.org/article/9b5fdbddffce4147bd33ae845aee2c76 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822008000300020 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822008000300020 0037-8682 1678-9849 https://doaj.org/article/9b5fdbddffce4147bd33ae845aee2c76 Revista da Sociedade Brasileira de Medicina Tropical, Vol 41, Iss 3, Pp 315-319 (2008) Trypanosoma cruzi Infecção chagásica Testes diagnósticos rápidos Sorologia Doença de Chagas Chagas infection Rapid diagnostic tests Serology Chagas disease Arctic medicine. Tropical medicine RC955-962 article 2008 ftdoajarticles https://doi.org/10.1590/S0037-86822008000300020 2022-12-31T02:57:38Z Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic. Moreover, in most places, neither blood banks nor healthcare units offer diagnostic confirmation or treatment access. By the time patients present clinical manifestations of advanced chronic Chagas disease, specific treatment with current drugs usually has limited effectiveness. Better-quality serological assays are urgently needed, especially rapid diagnostic tests for diagnosis patients in both acute and chronic phases, as well as for confirming that a parasitological cure has been achieved. Some new antigen combinations look promising and it is important to assess which ones are potentially the best, together with their requirements in terms of investigation and development. In August 2007, a group of specialized researchers and healthcare professionals met to discuss the state of Chagas infection diagnosis and to build a consensus for a plan of action to develop efficient, affordable, accessible and easy-to-use diagnostic tests for Chagas disease. This technical report presents the conclusions from that meeting. A infecção pelo Trypanosoma cruzi não é comumente detectada cedo ou diagnosticada ativamente, em parte porque a maioria dos infectados é assintomática ou oligossintomática e nem os bancos de sangue nem as unidades de saúde oferecem, na maioria dos lugares, nem a confirmação do diagnóstico nem o acesso ao tratamento. Habitualmente, quando os pacientes apresentam manifestações clínicas avançadas da doença crônica o tratamento específico com os medicamentos atuais tem efetividade limitada. São necessárias urgentemente provas sorológicas de melhor qualidade, e em especial provas diagnósticas rápidas, para diagnosticar pacientes na fase aguda e crônica, assim como para confirmar a cura parasitológica. Algumas novas combinações de antígenos são promissoras e é importante avaliar as potencialmente melhores, assim como as suas necessidades em ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Aguda ENVELOPE(-26.750,-26.750,-76.150,-76.150) Revista da Sociedade Brasileira de Medicina Tropical 41 3 315 319 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Trypanosoma cruzi Infecção chagásica Testes diagnósticos rápidos Sorologia Doença de Chagas Chagas infection Rapid diagnostic tests Serology Chagas disease Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Trypanosoma cruzi Infecção chagásica Testes diagnósticos rápidos Sorologia Doença de Chagas Chagas infection Rapid diagnostic tests Serology Chagas disease Arctic medicine. Tropical medicine RC955-962 International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
topic_facet |
Trypanosoma cruzi Infecção chagásica Testes diagnósticos rápidos Sorologia Doença de Chagas Chagas infection Rapid diagnostic tests Serology Chagas disease Arctic medicine. Tropical medicine RC955-962 |
description |
Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic. Moreover, in most places, neither blood banks nor healthcare units offer diagnostic confirmation or treatment access. By the time patients present clinical manifestations of advanced chronic Chagas disease, specific treatment with current drugs usually has limited effectiveness. Better-quality serological assays are urgently needed, especially rapid diagnostic tests for diagnosis patients in both acute and chronic phases, as well as for confirming that a parasitological cure has been achieved. Some new antigen combinations look promising and it is important to assess which ones are potentially the best, together with their requirements in terms of investigation and development. In August 2007, a group of specialized researchers and healthcare professionals met to discuss the state of Chagas infection diagnosis and to build a consensus for a plan of action to develop efficient, affordable, accessible and easy-to-use diagnostic tests for Chagas disease. This technical report presents the conclusions from that meeting. A infecção pelo Trypanosoma cruzi não é comumente detectada cedo ou diagnosticada ativamente, em parte porque a maioria dos infectados é assintomática ou oligossintomática e nem os bancos de sangue nem as unidades de saúde oferecem, na maioria dos lugares, nem a confirmação do diagnóstico nem o acesso ao tratamento. Habitualmente, quando os pacientes apresentam manifestações clínicas avançadas da doença crônica o tratamento específico com os medicamentos atuais tem efetividade limitada. São necessárias urgentemente provas sorológicas de melhor qualidade, e em especial provas diagnósticas rápidas, para diagnosticar pacientes na fase aguda e crônica, assim como para confirmar a cura parasitológica. Algumas novas combinações de antígenos são promissoras e é importante avaliar as potencialmente melhores, assim como as suas necessidades em ... |
format |
Article in Journal/Newspaper |
title |
International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
title_short |
International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
title_full |
International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
title_fullStr |
International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
title_full_unstemmed |
International meeting: new diagnostic tests are urgently needed to treat patients with Chagas disease Reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de Chagas |
title_sort |
international meeting: new diagnostic tests are urgently needed to treat patients with chagas disease reunião internacional: novos testes diagnósticos são necessários urgentemente para tratar pacientes com doença de chagas |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2008 |
url |
https://doi.org/10.1590/S0037-86822008000300020 https://doaj.org/article/9b5fdbddffce4147bd33ae845aee2c76 |
long_lat |
ENVELOPE(-26.750,-26.750,-76.150,-76.150) |
geographic |
Arctic Aguda |
geographic_facet |
Arctic Aguda |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 41, Iss 3, Pp 315-319 (2008) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822008000300020 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822008000300020 0037-8682 1678-9849 https://doaj.org/article/9b5fdbddffce4147bd33ae845aee2c76 |
op_doi |
https://doi.org/10.1590/S0037-86822008000300020 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
41 |
container_issue |
3 |
container_start_page |
315 |
op_container_end_page |
319 |
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