Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil
The prevalence of rubella antibodies was evaluated through a ramdom Seroepidemiological survey in 1400 blood samples of 2-14 year old children and in 329 samples of umbilical cord serum. Rubella IgG antibodies were detected by ELISA, and the sera were collected in 1987, five years before the mass va...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
1994
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Online Access: | https://doi.org/10.1590/S0036-46651994000400011 https://doaj.org/article/9b57880baf5149179c21e6b8ae4eaf3a |
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ftdoajarticles:oai:doaj.org/article:9b57880baf5149179c21e6b8ae4eaf3a 2024-09-09T19:28:38+00:00 Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil Vanda A.U.F. Souza José Cassio Moraes Laura M Sumita Maria Claudia C. Camargo Maria Cristina D.S. Fink Neuma T. R. Hidalgo Claudio S. Pannuti 1994-08-01T00:00:00Z https://doi.org/10.1590/S0036-46651994000400011 https://doaj.org/article/9b57880baf5149179c21e6b8ae4eaf3a EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651994000400011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651994000400011 0036-4665 1678-9946 https://doaj.org/article/9b57880baf5149179c21e6b8ae4eaf3a Revista do Instituto de Medicina Tropical de São Paulo, Vol 36, Iss 4, Pp 373-376 (1994) Rubella Seroprevalence Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1994 ftdoajarticles https://doi.org/10.1590/S0036-46651994000400011 2024-08-05T17:49:30Z The prevalence of rubella antibodies was evaluated through a ramdom Seroepidemiological survey in 1400 blood samples of 2-14 year old children and in 329 samples of umbilical cord serum. Rubella IgG antibodies were detected by ELISA, and the sera were collected in 1987, five years before the mass vaccination campaign with measles-mumps-rubella vaccine carried out in the city of São Paulo in 1992. A significant increase in prevalence of rubella infection was observed after 6 years of age, and 77% of the individuals aged from 15 to 19 years had detectable rubella antibodies. However, the seroprevalence rose to 90.5% (171/189) in cord serum samples from children whose mothers were 20 to 29 years old, and reached 95.6% in newborns of mothers who were 30 to 34 years old, indicating that a large number of women are infected during childbearing years. This study confirms that rubella infection represents an important Public Health problem in São Paulo city. The data on the seroprevalence of rubella antibodies before the mass vaccination campaign reflects the baseline immunological status of this population before any intervention and should be used to design an adequate vaccination strategy and to assess the Seroepidemiological impact of this intervention. A prevalência de anticorpos contra o vírus da rubéola foi avaliada através de inquérito soroepidemiológico, em 1400 amostras de sangue de crianças com idade entre 2 e 14 anos e 329 amostras de soro de cordão umbilical. Anticorpos para o vírus da rubéola foram detectados pela técnica de ELISA e as amostras foram colhidas em 1987, 5 anos antes da campanha de vacinação em massa com a vacina tríplice viral realizada na cidade de São Paulo em 1992. Um aumento significativo na prevalência foi observado após 6 anos de idade, e 77% dos indivíduos entre 15 e 19 anos apresentaram anticorpos anti-rubéola. Entretanto, a soroprevalência elevou-se para 90,5% (171/189) em soros de cordão de crianças cujas mães apresentavam idade entre 20 e 29 anos, alcançando 95,6% no grupo etário ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 36 4 373 376 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Rubella Seroprevalence Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Rubella Seroprevalence Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Vanda A.U.F. Souza José Cassio Moraes Laura M Sumita Maria Claudia C. Camargo Maria Cristina D.S. Fink Neuma T. R. Hidalgo Claudio S. Pannuti Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
topic_facet |
Rubella Seroprevalence Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
The prevalence of rubella antibodies was evaluated through a ramdom Seroepidemiological survey in 1400 blood samples of 2-14 year old children and in 329 samples of umbilical cord serum. Rubella IgG antibodies were detected by ELISA, and the sera were collected in 1987, five years before the mass vaccination campaign with measles-mumps-rubella vaccine carried out in the city of São Paulo in 1992. A significant increase in prevalence of rubella infection was observed after 6 years of age, and 77% of the individuals aged from 15 to 19 years had detectable rubella antibodies. However, the seroprevalence rose to 90.5% (171/189) in cord serum samples from children whose mothers were 20 to 29 years old, and reached 95.6% in newborns of mothers who were 30 to 34 years old, indicating that a large number of women are infected during childbearing years. This study confirms that rubella infection represents an important Public Health problem in São Paulo city. The data on the seroprevalence of rubella antibodies before the mass vaccination campaign reflects the baseline immunological status of this population before any intervention and should be used to design an adequate vaccination strategy and to assess the Seroepidemiological impact of this intervention. A prevalência de anticorpos contra o vírus da rubéola foi avaliada através de inquérito soroepidemiológico, em 1400 amostras de sangue de crianças com idade entre 2 e 14 anos e 329 amostras de soro de cordão umbilical. Anticorpos para o vírus da rubéola foram detectados pela técnica de ELISA e as amostras foram colhidas em 1987, 5 anos antes da campanha de vacinação em massa com a vacina tríplice viral realizada na cidade de São Paulo em 1992. Um aumento significativo na prevalência foi observado após 6 anos de idade, e 77% dos indivíduos entre 15 e 19 anos apresentaram anticorpos anti-rubéola. Entretanto, a soroprevalência elevou-se para 90,5% (171/189) em soros de cordão de crianças cujas mães apresentavam idade entre 20 e 29 anos, alcançando 95,6% no grupo etário ... |
format |
Article in Journal/Newspaper |
author |
Vanda A.U.F. Souza José Cassio Moraes Laura M Sumita Maria Claudia C. Camargo Maria Cristina D.S. Fink Neuma T. R. Hidalgo Claudio S. Pannuti |
author_facet |
Vanda A.U.F. Souza José Cassio Moraes Laura M Sumita Maria Claudia C. Camargo Maria Cristina D.S. Fink Neuma T. R. Hidalgo Claudio S. Pannuti |
author_sort |
Vanda A.U.F. Souza |
title |
Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
title_short |
Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
title_full |
Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
title_fullStr |
Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
title_full_unstemmed |
Prevalence of rubella antibodies in a non-immunized urban population, São Paulo, Brazil Prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, São Paulo, Brasil |
title_sort |
prevalence of rubella antibodies in a non-immunized urban population, são paulo, brazil prevalência de anticorpos anti-vírus da rubéola em população urbana não imunizada, são paulo, brasil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1994 |
url |
https://doi.org/10.1590/S0036-46651994000400011 https://doaj.org/article/9b57880baf5149179c21e6b8ae4eaf3a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 36, Iss 4, Pp 373-376 (1994) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651994000400011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651994000400011 0036-4665 1678-9946 https://doaj.org/article/9b57880baf5149179c21e6b8ae4eaf3a |
op_doi |
https://doi.org/10.1590/S0036-46651994000400011 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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36 |
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