Acute exacerbation in chronic hepatitis B virus infection
A case of an acute exacerbation of liver injury in a chronic HBV infected young male is reported. The correlation between the severe symptomatic hepatitis is done with the histopathologic findings of extense areas of bridging necrosis on the Iwer biopsy. The serological pattern for markers of HBV (H...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1996
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Online Access: | https://doi.org/10.1590/S0037-86821996000300009 https://doaj.org/article/9b37862040ec425f967d1619a03cc6fb |
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ftdoajarticles:oai:doaj.org/article:9b37862040ec425f967d1619a03cc6fb 2023-05-15T15:04:43+02:00 Acute exacerbation in chronic hepatitis B virus infection Marcio Vieira Santos Maria Irma Seixas Duarte Antonio Alci Barone 1996-06-01T00:00:00Z https://doi.org/10.1590/S0037-86821996000300009 https://doaj.org/article/9b37862040ec425f967d1619a03cc6fb EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000300009&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86821996000300009 https://doaj.org/article/9b37862040ec425f967d1619a03cc6fb Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 3, Pp 275-279 (1996) Exacerbação aguda Soroconversão AgHBe-anti Hb e Infecção crônica pelo VHB Arctic medicine. Tropical medicine RC955-962 article 1996 ftdoajarticles https://doi.org/10.1590/S0037-86821996000300009 2022-12-31T03:21:36Z A case of an acute exacerbation of liver injury in a chronic HBV infected young male is reported. The correlation between the severe symptomatic hepatitis is done with the histopathologic findings of extense areas of bridging necrosis on the Iwer biopsy. The serological pattern for markers of HBV (HBsAg +, anti HBs g -, HBeAg -, anti HBe +, anti HBcIgG + and IgM -) confirm a chronic infection, ana the authors propose that the episode of severe hepatitis relates to the recent spontaneous seroconvertion of HBe Ag to anti HBe. Other causes of hepatitis were excluded, and the control liver biopsy (6 months later) showed normalization of hepatic architecture and absence of markers of viral replication in tissue and serum. A review of literature is done in an attempt to elucidate the diagnostic possibilities in this case, with emphasis on new immunoassays useful in differentiating between acute hepatitis B and acute exacerbation of a chronic hepatitis by the same virus. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Aguda ENVELOPE(-26.750,-26.750,-76.150,-76.150) Revista da Sociedade Brasileira de Medicina Tropical 29 3 275 279 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Exacerbação aguda Soroconversão AgHBe-anti Hb e Infecção crônica pelo VHB Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Exacerbação aguda Soroconversão AgHBe-anti Hb e Infecção crônica pelo VHB Arctic medicine. Tropical medicine RC955-962 Marcio Vieira Santos Maria Irma Seixas Duarte Antonio Alci Barone Acute exacerbation in chronic hepatitis B virus infection |
topic_facet |
Exacerbação aguda Soroconversão AgHBe-anti Hb e Infecção crônica pelo VHB Arctic medicine. Tropical medicine RC955-962 |
description |
A case of an acute exacerbation of liver injury in a chronic HBV infected young male is reported. The correlation between the severe symptomatic hepatitis is done with the histopathologic findings of extense areas of bridging necrosis on the Iwer biopsy. The serological pattern for markers of HBV (HBsAg +, anti HBs g -, HBeAg -, anti HBe +, anti HBcIgG + and IgM -) confirm a chronic infection, ana the authors propose that the episode of severe hepatitis relates to the recent spontaneous seroconvertion of HBe Ag to anti HBe. Other causes of hepatitis were excluded, and the control liver biopsy (6 months later) showed normalization of hepatic architecture and absence of markers of viral replication in tissue and serum. A review of literature is done in an attempt to elucidate the diagnostic possibilities in this case, with emphasis on new immunoassays useful in differentiating between acute hepatitis B and acute exacerbation of a chronic hepatitis by the same virus. |
format |
Article in Journal/Newspaper |
author |
Marcio Vieira Santos Maria Irma Seixas Duarte Antonio Alci Barone |
author_facet |
Marcio Vieira Santos Maria Irma Seixas Duarte Antonio Alci Barone |
author_sort |
Marcio Vieira Santos |
title |
Acute exacerbation in chronic hepatitis B virus infection |
title_short |
Acute exacerbation in chronic hepatitis B virus infection |
title_full |
Acute exacerbation in chronic hepatitis B virus infection |
title_fullStr |
Acute exacerbation in chronic hepatitis B virus infection |
title_full_unstemmed |
Acute exacerbation in chronic hepatitis B virus infection |
title_sort |
acute exacerbation in chronic hepatitis b virus infection |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1996 |
url |
https://doi.org/10.1590/S0037-86821996000300009 https://doaj.org/article/9b37862040ec425f967d1619a03cc6fb |
long_lat |
ENVELOPE(-26.750,-26.750,-76.150,-76.150) |
geographic |
Arctic Aguda |
geographic_facet |
Arctic Aguda |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 3, Pp 275-279 (1996) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000300009&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86821996000300009 https://doaj.org/article/9b37862040ec425f967d1619a03cc6fb |
op_doi |
https://doi.org/10.1590/S0037-86821996000300009 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
29 |
container_issue |
3 |
container_start_page |
275 |
op_container_end_page |
279 |
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1766336456957100032 |