Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014.
BACKGROUND:Scrub typhus is endemic in the Asia-Pacific region including China, and the number of reported cases has increased dramatically in the past decade. However, the spatial-temporal dynamics and the potential risk factors in transmission of scrub typhus in mainland China have yet to be charac...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0004875 https://doaj.org/article/999725cae649429bb19ac1bfb47e8025 |
id |
ftdoajarticles:oai:doaj.org/article:999725cae649429bb19ac1bfb47e8025 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:999725cae649429bb19ac1bfb47e8025 2023-05-15T15:11:40+02:00 Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. Yi-Cheng Wu Quan Qian Ricardo J Soares Magalhaes Zhi-Hai Han Wen-Biao Hu Ubydul Haque Thomas A Weppelmann Yong Wang Yun-Xi Liu Xin-Lou Li Hai-Long Sun Yan-Song Sun Archie C A Clements Shen-Long Li Wen-Yi Zhang 2016-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004875 https://doaj.org/article/999725cae649429bb19ac1bfb47e8025 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4968795?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004875 https://doaj.org/article/999725cae649429bb19ac1bfb47e8025 PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004875 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004875 2022-12-31T04:15:03Z BACKGROUND:Scrub typhus is endemic in the Asia-Pacific region including China, and the number of reported cases has increased dramatically in the past decade. However, the spatial-temporal dynamics and the potential risk factors in transmission of scrub typhus in mainland China have yet to be characterized. OBJECTIVE:This study aims to explore the spatiotemporal dynamics of reported scrub typhus cases in mainland China between January 2006 and December 2014, to detect the location of high risk spatiotemporal clusters of scrub typhus cases, and identify the potential risk factors affecting the re-emergence of the disease. METHOD:Monthly cases of scrub typhus reported at the county level between 2006 and 2014 were obtained from the Chinese Center for Diseases Control and Prevention. Time-series analyses, spatiotemporal cluster analyses, and spatial scan statistics were used to explore the characteristics of the scrub typhus incidence. To explore the association between scrub typhus incidence and environmental variables panel Poisson regression analysis was conducted. RESULTS:During the time period between 2006 and 2014 a total of 54,558 scrub typhus cases were reported in mainland China, which grew exponentially. The majority of cases were reported each year between July and November, with peak incidence during October every year. The spatiotemporal dynamics of scrub typhus varied over the study period with high-risk clusters identified in southwest, southern, and middle-eastern part of China. Scrub typhus incidence was positively correlated with the percentage of shrub and meteorological variables including temperature and precipitation. CONCLUSIONS:The results of this study demonstrate areas in China that could be targeted with public health interventions to mitigate the growing threat of scrub typhus in the country. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific PLOS Neglected Tropical Diseases 10 8 e0004875 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Yi-Cheng Wu Quan Qian Ricardo J Soares Magalhaes Zhi-Hai Han Wen-Biao Hu Ubydul Haque Thomas A Weppelmann Yong Wang Yun-Xi Liu Xin-Lou Li Hai-Long Sun Yan-Song Sun Archie C A Clements Shen-Long Li Wen-Yi Zhang Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Scrub typhus is endemic in the Asia-Pacific region including China, and the number of reported cases has increased dramatically in the past decade. However, the spatial-temporal dynamics and the potential risk factors in transmission of scrub typhus in mainland China have yet to be characterized. OBJECTIVE:This study aims to explore the spatiotemporal dynamics of reported scrub typhus cases in mainland China between January 2006 and December 2014, to detect the location of high risk spatiotemporal clusters of scrub typhus cases, and identify the potential risk factors affecting the re-emergence of the disease. METHOD:Monthly cases of scrub typhus reported at the county level between 2006 and 2014 were obtained from the Chinese Center for Diseases Control and Prevention. Time-series analyses, spatiotemporal cluster analyses, and spatial scan statistics were used to explore the characteristics of the scrub typhus incidence. To explore the association between scrub typhus incidence and environmental variables panel Poisson regression analysis was conducted. RESULTS:During the time period between 2006 and 2014 a total of 54,558 scrub typhus cases were reported in mainland China, which grew exponentially. The majority of cases were reported each year between July and November, with peak incidence during October every year. The spatiotemporal dynamics of scrub typhus varied over the study period with high-risk clusters identified in southwest, southern, and middle-eastern part of China. Scrub typhus incidence was positively correlated with the percentage of shrub and meteorological variables including temperature and precipitation. CONCLUSIONS:The results of this study demonstrate areas in China that could be targeted with public health interventions to mitigate the growing threat of scrub typhus in the country. |
format |
Article in Journal/Newspaper |
author |
Yi-Cheng Wu Quan Qian Ricardo J Soares Magalhaes Zhi-Hai Han Wen-Biao Hu Ubydul Haque Thomas A Weppelmann Yong Wang Yun-Xi Liu Xin-Lou Li Hai-Long Sun Yan-Song Sun Archie C A Clements Shen-Long Li Wen-Yi Zhang |
author_facet |
Yi-Cheng Wu Quan Qian Ricardo J Soares Magalhaes Zhi-Hai Han Wen-Biao Hu Ubydul Haque Thomas A Weppelmann Yong Wang Yun-Xi Liu Xin-Lou Li Hai-Long Sun Yan-Song Sun Archie C A Clements Shen-Long Li Wen-Yi Zhang |
author_sort |
Yi-Cheng Wu |
title |
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
title_short |
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
title_full |
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
title_fullStr |
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
title_full_unstemmed |
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014. |
title_sort |
spatiotemporal dynamics of scrub typhus transmission in mainland china, 2006-2014. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004875 https://doaj.org/article/999725cae649429bb19ac1bfb47e8025 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004875 (2016) |
op_relation |
http://europepmc.org/articles/PMC4968795?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004875 https://doaj.org/article/999725cae649429bb19ac1bfb47e8025 |
op_doi |
https://doi.org/10.1371/journal.pntd.0004875 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
10 |
container_issue |
8 |
container_start_page |
e0004875 |
_version_ |
1766342496781074432 |