Negative regulation of Schistosoma japonicum egg-induced liver fibrosis by natural killer cells.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Xin Hou, Fazhi Yu, Suqin Man, Dake Huang, Yuxia Zhang, Miao Liu, Cuiping Ren, Jijia Shen
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2012
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Rae
• Online Access: https://doi.org/10.1371/journal.pntd.0001456; https://doaj.org/article/98ffeaef6fdd46cc85e9f6bb4376b529

The role of natural killer (NK) cells in infection-induced liver fibrosis remains obscure. In this study, we elucidated the effect of NK cells on Schistosoma japonicum (S. japonicum) egg-induced liver fibrosis. Liver fibrosis was induced by infecting C57BL/6 mice with 18-20 cercariae of S. japonicum...