The indeterminate form of human chronic Chagas' disease: a clinical epidemological review
Data on the epidemiology and the natural history of the indeterminate form of human chronic Chagas' disease (IFCCD) are discussed, revealing its great importance in endemic areas of Brazil. The work shows that IFCCD presents a gradual and very slow course, causing a benign picture in the studie...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1989
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ftdoajarticles:oai:doaj.org/article:98e98e62b71749c4ba7a482359008eba 2023-05-15T15:15:35+02:00 The indeterminate form of human chronic Chagas' disease: a clinical epidemological review João Carlos Pinto Dias 1989-09-01T00:00:00Z https://doaj.org/article/98e98e62b71749c4ba7a482359008eba EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821989000300007 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/98e98e62b71749c4ba7a482359008eba Revista da Sociedade Brasileira de Medicina Tropical, Vol 22, Iss 3, Pp 147-156 (1989) Doença de Chagas Forma indeterminada Prognóstico Fatores de evolução Chagas' disease Indeterminante form Prognosis Evolution factors Arctic medicine. Tropical medicine RC955-962 article 1989 ftdoajarticles 2022-12-31T02:53:15Z Data on the epidemiology and the natural history of the indeterminate form of human chronic Chagas' disease (IFCCD) are discussed, revealing its great importance in endemic areas of Brazil. The work shows that IFCCD presents a gradual and very slow course, causing a benign picture in the studied patients. Evolution patterns, prognostic and anatomopathological features are also discussed. For practical purposes, the classical concept of IFCCD proved to be simple, operational and consistent, It is defined by the absence of symptoms and clinical findings in chronic infected patients with positive serology and/or parasitological examinations for Trypanosoma cruzi coupled with normal electrocardiographic and radiological exams (heart, oesophagus and colon X-Rays). If a patient is submitted to more rigorous and sophisticated tests, these can reveal some alterations, generally small ones and unable to interfere with the prognosis of the infection. It is suggested that research lines specially related to the evolution ary factors and immunological involvement during this phase be adopted. Analisam-se epidemiologia e a história natural da forma indeterminada da doença de Chagas (FCI), confirmando-se sua grande importância epidemiológica em áreas endêmicas da tripanosomose, no Brasil. Os dados mostram que a evolução da FCI é geralmente lenta, com bom prognóstico, discutindo-se alguns fatores evolutivos, o prognóstico e o substrato anatomopatológico desta entidade. Sob o prisma prático, verifica-se que o conceito clássico da FCI se mostra simples, consistente e operacional: define-se no paciente crônico e assintomático, portador de provas sorológicas e/ou parasitológicaspositivas para T. cruzi, com exames clínico, eletrocardiográfico e radiológico (área cardíaca, esófago e cólon) normais. Exames outros mais rigorosos e sofisticados podem demonstrar algumas alterações e anormalidades nestes pacientes, geralmente discretas e pouco interferentes no prognóstico. Fazem-se algumas sugestões de pesquisa sobre a FCI, ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Prisma ENVELOPE(-58.767,-58.767,-69.200,-69.200) Sob’ ENVELOPE(66.156,66.156,66.322,66.322) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Doença de Chagas Forma indeterminada Prognóstico Fatores de evolução Chagas' disease Indeterminante form Prognosis Evolution factors Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Doença de Chagas Forma indeterminada Prognóstico Fatores de evolução Chagas' disease Indeterminante form Prognosis Evolution factors Arctic medicine. Tropical medicine RC955-962 João Carlos Pinto Dias The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
topic_facet |
Doença de Chagas Forma indeterminada Prognóstico Fatores de evolução Chagas' disease Indeterminante form Prognosis Evolution factors Arctic medicine. Tropical medicine RC955-962 |
description |
Data on the epidemiology and the natural history of the indeterminate form of human chronic Chagas' disease (IFCCD) are discussed, revealing its great importance in endemic areas of Brazil. The work shows that IFCCD presents a gradual and very slow course, causing a benign picture in the studied patients. Evolution patterns, prognostic and anatomopathological features are also discussed. For practical purposes, the classical concept of IFCCD proved to be simple, operational and consistent, It is defined by the absence of symptoms and clinical findings in chronic infected patients with positive serology and/or parasitological examinations for Trypanosoma cruzi coupled with normal electrocardiographic and radiological exams (heart, oesophagus and colon X-Rays). If a patient is submitted to more rigorous and sophisticated tests, these can reveal some alterations, generally small ones and unable to interfere with the prognosis of the infection. It is suggested that research lines specially related to the evolution ary factors and immunological involvement during this phase be adopted. Analisam-se epidemiologia e a história natural da forma indeterminada da doença de Chagas (FCI), confirmando-se sua grande importância epidemiológica em áreas endêmicas da tripanosomose, no Brasil. Os dados mostram que a evolução da FCI é geralmente lenta, com bom prognóstico, discutindo-se alguns fatores evolutivos, o prognóstico e o substrato anatomopatológico desta entidade. Sob o prisma prático, verifica-se que o conceito clássico da FCI se mostra simples, consistente e operacional: define-se no paciente crônico e assintomático, portador de provas sorológicas e/ou parasitológicaspositivas para T. cruzi, com exames clínico, eletrocardiográfico e radiológico (área cardíaca, esófago e cólon) normais. Exames outros mais rigorosos e sofisticados podem demonstrar algumas alterações e anormalidades nestes pacientes, geralmente discretas e pouco interferentes no prognóstico. Fazem-se algumas sugestões de pesquisa sobre a FCI, ... |
format |
Article in Journal/Newspaper |
author |
João Carlos Pinto Dias |
author_facet |
João Carlos Pinto Dias |
author_sort |
João Carlos Pinto Dias |
title |
The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
title_short |
The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
title_full |
The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
title_fullStr |
The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
title_full_unstemmed |
The indeterminate form of human chronic Chagas' disease: a clinical epidemological review |
title_sort |
indeterminate form of human chronic chagas' disease: a clinical epidemological review |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1989 |
url |
https://doaj.org/article/98e98e62b71749c4ba7a482359008eba |
long_lat |
ENVELOPE(-58.767,-58.767,-69.200,-69.200) ENVELOPE(66.156,66.156,66.322,66.322) |
geographic |
Arctic Prisma Sob’ |
geographic_facet |
Arctic Prisma Sob’ |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 22, Iss 3, Pp 147-156 (1989) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821989000300007 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/98e98e62b71749c4ba7a482359008eba |
_version_ |
1766345953376206848 |