Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection
ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory in...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical (SBMT)
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Online Access: | https://doi.org/10.1590/0037-8682-0008-2023 https://doaj.org/article/989902889cca4bf5be6f5f523262b6ed |
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ftdoajarticles:oai:doaj.org/article:989902889cca4bf5be6f5f523262b6ed 2023-07-02T03:31:26+02:00 Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection José Wagner Leonel Tavares-Júnior José Carlos Jucá Pompeu Filho Luiz Eduardo Garcia Galvão 2023-06-01T00:00:00Z https://doi.org/10.1590/0037-8682-0008-2023 https://doaj.org/article/989902889cca4bf5be6f5f523262b6ed EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100703&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0008-2023 https://doaj.org/article/989902889cca4bf5be6f5f523262b6ed Revista da Sociedade Brasileira de Medicina Tropical, Vol 56 (2023) COVID-19 Nirmatrelvir/ritonavir Erythema multiforme Arctic medicine. Tropical medicine RC955-962 article 2023 ftdoajarticles https://doi.org/10.1590/0037-8682-0008-2023 2023-06-11T00:36:28Z ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 56 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
COVID-19 Nirmatrelvir/ritonavir Erythema multiforme Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
COVID-19 Nirmatrelvir/ritonavir Erythema multiforme Arctic medicine. Tropical medicine RC955-962 José Wagner Leonel Tavares-Júnior José Carlos Jucá Pompeu Filho Luiz Eduardo Garcia Galvão Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
topic_facet |
COVID-19 Nirmatrelvir/ritonavir Erythema multiforme Arctic medicine. Tropical medicine RC955-962 |
description |
ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response. |
format |
Article in Journal/Newspaper |
author |
José Wagner Leonel Tavares-Júnior José Carlos Jucá Pompeu Filho Luiz Eduardo Garcia Galvão |
author_facet |
José Wagner Leonel Tavares-Júnior José Carlos Jucá Pompeu Filho Luiz Eduardo Garcia Galvão |
author_sort |
José Wagner Leonel Tavares-Júnior |
title |
Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
title_short |
Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
title_full |
Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
title_fullStr |
Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
title_full_unstemmed |
Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
title_sort |
post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2023 |
url |
https://doi.org/10.1590/0037-8682-0008-2023 https://doaj.org/article/989902889cca4bf5be6f5f523262b6ed |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 56 (2023) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100703&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0008-2023 https://doaj.org/article/989902889cca4bf5be6f5f523262b6ed |
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https://doi.org/10.1590/0037-8682-0008-2023 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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56 |
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