Evaluation of the schistosomicidal efficacy of liposome - Entrapped Oxamniquine

Oxamniquine (OXA) was sucessfully encapsulated in small unilamellar vesicles using a pH gradient method. This procedure led to a high drug encapsulation efficiency (> 85%) at a drug to lipid molar ratio of 1/10. Moreover, these liposomes were found to retain encapsulated OXA efficciently under di...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Frédéric Frézard, Alan Lane de Melo
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 1997
Subjects:
Schistosoma mansoni
Schistosomiasis
Liposome
Oxamniquine
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Alta
Arctic
Droga
Sob’
Online Access:https://doi.org/10.1590/S0036-46651997000200006
https://doaj.org/article/9724873500e84b0cbba1e944e47bc30f

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