Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013
ABSTRACT This study documented the number and results of mycobacterial culture and drug sensitivity testing (CDST) in Mexico from 2009–2013 and assessed whether states with a higher risk of multidrug-resistant tuberculosis (MDR-TB) performed more CDST and had more cultures showing MDR-TB. Data for t...
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ftdoajarticles:oai:doaj.org/article:96fe335649104148b70e817bcfd5294d 2023-05-15T15:13:29+02:00 Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 Ivonne Orejel Martin Castellanos Diana Marín Alberto Mendoza Anthony D. Harries https://doaj.org/article/96fe335649104148b70e817bcfd5294d EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016000100065&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/96fe335649104148b70e817bcfd5294d Revista Panamericana de Salud Pública, Vol 39, Iss 1, Pp 65-68 Tuberculosis técnicas de cultivo pruebas de sensibilidad microbiana tuberculosis resistente a múltiples medicamentos tuberculosis extensivamente resistente a drogas investigación operativa México Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article ftdoajarticles 2022-12-31T13:22:41Z ABSTRACT This study documented the number and results of mycobacterial culture and drug sensitivity testing (CDST) in Mexico from 2009–2013 and assessed whether states with a higher risk of multidrug-resistant tuberculosis (MDR-TB) performed more CDST and had more cultures showing MDR-TB. Data for this longitudinal, descriptive, operational research study came from the electronic records of 31 state public health laboratories in Mexico. The total number of CDSTs was 6 470, increasing from 2 143 in the first 2 years to 4 327 in the latter 3 years. There was a significant increase in the proportion of cultures showing sensitivity to all drugs, from 53.1% to 60.9% in 2011–2013 (P < 0.001) and a significant decrease in the proportion showing MDR-TB, from 28.2% in 2009 to 19.8% in 2013 (P < 0.001). Cases of extensively drug resistant tuberculosis were < 1% per year. In the 12 states with higher risk for MDR-TB, significantly more CDSTs (2 382 test) were done in 2011–2013 than in the other 19 states (1 945 tests). Also, for each year the proportion of cultures showing MDR-TB was significantly higher in high risk MDR-TB states than in lower risk ones (P < 0.001). During the 5-year study period, CDST was scaled up in Mexico, particularly in high-risk MDR-TB states where a higher proportion of cultures showed MDR-TB. Scale up and wider coverage of CDST should continue. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Tuberculosis técnicas de cultivo pruebas de sensibilidad microbiana tuberculosis resistente a múltiples medicamentos tuberculosis extensivamente resistente a drogas investigación operativa México Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Tuberculosis técnicas de cultivo pruebas de sensibilidad microbiana tuberculosis resistente a múltiples medicamentos tuberculosis extensivamente resistente a drogas investigación operativa México Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Ivonne Orejel Martin Castellanos Diana Marín Alberto Mendoza Anthony D. Harries Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
topic_facet |
Tuberculosis técnicas de cultivo pruebas de sensibilidad microbiana tuberculosis resistente a múltiples medicamentos tuberculosis extensivamente resistente a drogas investigación operativa México Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
ABSTRACT This study documented the number and results of mycobacterial culture and drug sensitivity testing (CDST) in Mexico from 2009–2013 and assessed whether states with a higher risk of multidrug-resistant tuberculosis (MDR-TB) performed more CDST and had more cultures showing MDR-TB. Data for this longitudinal, descriptive, operational research study came from the electronic records of 31 state public health laboratories in Mexico. The total number of CDSTs was 6 470, increasing from 2 143 in the first 2 years to 4 327 in the latter 3 years. There was a significant increase in the proportion of cultures showing sensitivity to all drugs, from 53.1% to 60.9% in 2011–2013 (P < 0.001) and a significant decrease in the proportion showing MDR-TB, from 28.2% in 2009 to 19.8% in 2013 (P < 0.001). Cases of extensively drug resistant tuberculosis were < 1% per year. In the 12 states with higher risk for MDR-TB, significantly more CDSTs (2 382 test) were done in 2011–2013 than in the other 19 states (1 945 tests). Also, for each year the proportion of cultures showing MDR-TB was significantly higher in high risk MDR-TB states than in lower risk ones (P < 0.001). During the 5-year study period, CDST was scaled up in Mexico, particularly in high-risk MDR-TB states where a higher proportion of cultures showed MDR-TB. Scale up and wider coverage of CDST should continue. |
format |
Article in Journal/Newspaper |
author |
Ivonne Orejel Martin Castellanos Diana Marín Alberto Mendoza Anthony D. Harries |
author_facet |
Ivonne Orejel Martin Castellanos Diana Marín Alberto Mendoza Anthony D. Harries |
author_sort |
Ivonne Orejel |
title |
Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
title_short |
Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
title_full |
Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
title_fullStr |
Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
title_full_unstemmed |
Culture and drug sensitivity testing among patients with pulmonary tuberculosis in Mexico: national data for 2009–2013 |
title_sort |
culture and drug sensitivity testing among patients with pulmonary tuberculosis in mexico: national data for 2009–2013 |
publisher |
Pan American Health Organization |
url |
https://doaj.org/article/96fe335649104148b70e817bcfd5294d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 39, Iss 1, Pp 65-68 |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016000100065&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/96fe335649104148b70e817bcfd5294d |
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1766344043054235648 |