The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum

• Published in: Malaria Journal
• Main Authors: Kiechel Jean, Konaté Amadou T, Ouédraogo Amidou, Diarra Amidou, Gansané Adama, Tiono Alfred B, Sirima Sodiomon B, Morgan Caroline C, Olliaro Piero L, Taylor Walter RJ
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2009
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Meier
• Online Access: https://doi.org/10.1186/1475-2875-8-48; https://doaj.org/article/95fed554d3034e95b72ec91cfb1efad9

Abstract Background Artesunate (AS) plus amodiaquine (AQ) is one artemisinin-based combination (ACT) recommended by the WHO for treating Plasmodium falciparum malaria. Fixed-dose AS/AQ is new, but its safety and efficacy are hitherto untested. Methods A randomized, open-label trial was conducted com...