Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age
BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in body weight and obesity. However, at the mome...
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Endocrinology Research Centre
2022
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ftdoajarticles:oai:doaj.org/article:95c5cfb73ea147f182ce202e27466f1a 2024-02-27T08:37:33+00:00 Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age A. A. Bichkaev N. I. Volkova F. A. Bichkaeva 2022-05-01T00:00:00Z https://doi.org/10.14341/omet12480 https://doaj.org/article/95c5cfb73ea147f182ce202e27466f1a EN RU eng rus Endocrinology Research Centre https://www.omet-endojournals.ru/jour/article/view/12480 https://doaj.org/toc/2071-8713 https://doaj.org/toc/2306-5524 2071-8713 2306-5524 doi:10.14341/omet12480 https://doaj.org/article/95c5cfb73ea147f182ce202e27466f1a Ожирение и метаболизм, Vol 19, Iss 1, Pp 35-46 (2022) glucose lactates pyruvates pancreatic hormones age gender arctic region Physiology QP1-981 Biochemistry QD415-436 article 2022 ftdoajarticles https://doi.org/10.14341/omet12480 2024-01-28T01:39:58Z BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in body weight and obesity. However, at the moment, there is no clear idea of the age range in the structure of metabolic changes in northerners, and the influence of gender on the content of glucose, its metabolites, pancreatic hormones and the nature of the relationship between them in adults requires clarification.AIMS: To assess the values of the parameters of carbohydrate metabolism, pancreatic hormones, body mass index and the nature of the relationships between them in residents of the Arctic region who were born and permanently residing in the Nenets (NAO), Yamalo-Nenets Autonomous Okrug (Yamalo-Nenets Autonomous Okrug (Yamalo-Nenets Autonomous Okrug) and Mezen District of the Arkhangelsk Region, taking into account gender and age.MATERIALS AND METHODS: In the blood serum healthy residents of the NAO, YaNAO and the Mezensky district of the Arkhangelsk region of mature age, born and permanently residing in the Arctic region, randomly selected after a medical examination and questioning, which depending on gender and age were divided into groups: women 21–35, 36–45, 46–55 years old and men 22–35, 36–45, 46–60 years old. The blood serum was determined by the content of glucose, lactate, pyruvate, insulin, proinsulin, C-peptide was determined, measured height and weight.RESULTS: The study involved 1146 people of mature age (women 21–35 (221), 36–45 (222) and 46–55 (371), men 22–35 (105), 36–45 (84), 46–60 (143) years). Regardless of gender, the content of glucose (Glu) significantly increases with age, the peak of which occurs in women aged 46–55 years and in men aged 46–60 years. Age-related changes in the content of lactate (Lac) and pyruvate (Pir) were not found, but in men aged 36–45 years, the level of Lac was higher than in women, and the content of Pir, ... Article in Journal/Newspaper Arctic Arkhangelsk nenets Nenets Autonomous Okrug Yamalo Nenets Yamalo-Nenets Autonomous Okrug Directory of Open Access Journals: DOAJ Articles Arctic Obesity and metabolism 19 1 35 46 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
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English Russian |
topic |
glucose lactates pyruvates pancreatic hormones age gender arctic region Physiology QP1-981 Biochemistry QD415-436 |
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glucose lactates pyruvates pancreatic hormones age gender arctic region Physiology QP1-981 Biochemistry QD415-436 A. A. Bichkaev N. I. Volkova F. A. Bichkaeva Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
topic_facet |
glucose lactates pyruvates pancreatic hormones age gender arctic region Physiology QP1-981 Biochemistry QD415-436 |
description |
BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in body weight and obesity. However, at the moment, there is no clear idea of the age range in the structure of metabolic changes in northerners, and the influence of gender on the content of glucose, its metabolites, pancreatic hormones and the nature of the relationship between them in adults requires clarification.AIMS: To assess the values of the parameters of carbohydrate metabolism, pancreatic hormones, body mass index and the nature of the relationships between them in residents of the Arctic region who were born and permanently residing in the Nenets (NAO), Yamalo-Nenets Autonomous Okrug (Yamalo-Nenets Autonomous Okrug (Yamalo-Nenets Autonomous Okrug) and Mezen District of the Arkhangelsk Region, taking into account gender and age.MATERIALS AND METHODS: In the blood serum healthy residents of the NAO, YaNAO and the Mezensky district of the Arkhangelsk region of mature age, born and permanently residing in the Arctic region, randomly selected after a medical examination and questioning, which depending on gender and age were divided into groups: women 21–35, 36–45, 46–55 years old and men 22–35, 36–45, 46–60 years old. The blood serum was determined by the content of glucose, lactate, pyruvate, insulin, proinsulin, C-peptide was determined, measured height and weight.RESULTS: The study involved 1146 people of mature age (women 21–35 (221), 36–45 (222) and 46–55 (371), men 22–35 (105), 36–45 (84), 46–60 (143) years). Regardless of gender, the content of glucose (Glu) significantly increases with age, the peak of which occurs in women aged 46–55 years and in men aged 46–60 years. Age-related changes in the content of lactate (Lac) and pyruvate (Pir) were not found, but in men aged 36–45 years, the level of Lac was higher than in women, and the content of Pir, ... |
format |
Article in Journal/Newspaper |
author |
A. A. Bichkaev N. I. Volkova F. A. Bichkaeva |
author_facet |
A. A. Bichkaev N. I. Volkova F. A. Bichkaeva |
author_sort |
A. A. Bichkaev |
title |
Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
title_short |
Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
title_full |
Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
title_fullStr |
Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
title_full_unstemmed |
Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age |
title_sort |
gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the arctic region, taking into account age |
publisher |
Endocrinology Research Centre |
publishDate |
2022 |
url |
https://doi.org/10.14341/omet12480 https://doaj.org/article/95c5cfb73ea147f182ce202e27466f1a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Arkhangelsk nenets Nenets Autonomous Okrug Yamalo Nenets Yamalo-Nenets Autonomous Okrug |
genre_facet |
Arctic Arkhangelsk nenets Nenets Autonomous Okrug Yamalo Nenets Yamalo-Nenets Autonomous Okrug |
op_source |
Ожирение и метаболизм, Vol 19, Iss 1, Pp 35-46 (2022) |
op_relation |
https://www.omet-endojournals.ru/jour/article/view/12480 https://doaj.org/toc/2071-8713 https://doaj.org/toc/2306-5524 2071-8713 2306-5524 doi:10.14341/omet12480 https://doaj.org/article/95c5cfb73ea147f182ce202e27466f1a |
op_doi |
https://doi.org/10.14341/omet12480 |
container_title |
Obesity and metabolism |
container_volume |
19 |
container_issue |
1 |
container_start_page |
35 |
op_container_end_page |
46 |
_version_ |
1792044535322247168 |