Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control
Abstract Background Insecticide treated bed nets are major tools for the Roll Back Malaria campaign. There are two types of Long-Lasting Insecticide-treated Nets (LNs) on the market: coated nets and insecticide-incorporated nets. Nets provided to this market need a recommendation from the World Heal...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2008
|
Subjects: | |
Online Access: | https://doi.org/10.1186/1475-2875-7-114 https://doaj.org/article/91a43a54d8a04d828c7a4bb746137196 |
id |
ftdoajarticles:oai:doaj.org/article:91a43a54d8a04d828c7a4bb746137196 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:91a43a54d8a04d828c7a4bb746137196 2023-05-15T15:15:40+02:00 Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control Pigeon Olivier Bonnet Julien Skovmand Ole Corbel Vincent 2008-06-01T00:00:00Z https://doi.org/10.1186/1475-2875-7-114 https://doaj.org/article/91a43a54d8a04d828c7a4bb746137196 EN eng BMC http://www.malariajournal.com/content/7/1/114 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-7-114 1475-2875 https://doaj.org/article/91a43a54d8a04d828c7a4bb746137196 Malaria Journal, Vol 7, Iss 1, p 114 (2008) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2008 ftdoajarticles https://doi.org/10.1186/1475-2875-7-114 2022-12-30T22:59:36Z Abstract Background Insecticide treated bed nets are major tools for the Roll Back Malaria campaign. There are two types of Long-Lasting Insecticide-treated Nets (LNs) on the market: coated nets and insecticide-incorporated nets. Nets provided to this market need a recommendation from the World Health Organization to be purchased by donors and NGOs. During laboratory study (phase I), the first step consists in evaluating the wash resistance of a new LN product. When insecticide-incorporated nets are washed, it takes time to regenerate the insecticidal activity, i.e. insecticide must migrate to the net surface to be accessible to mosquitoes. The interval of time required for regeneration must be carefully determined to ensure the accuracy of further results. WHOPES procedures currently recommend the determination of the regeneration time by using mortality data. However, as mortality cannot exceed 100%, a LN that regenerates a surface concentration exceeding the dosage for 100% mortality, will have its regeneration time underestimated. Methods The Median Knock Down Time (MKDT) was determined as function of insecticide dosage on an inert surface, glass, and on polyester nettings using an acetone solution or a simple emulsion. Dosage response was also established for mortality data. The same method was then applied to a commercially polyethylene netting, currently under WHOPES evaluation, to determine the dynamics of regeneration as function of repeated washings. The deltamethrin content of these nets was estimated by Capillary Gas Chromatography (GC-ECD). Results MKDT was a linear function of log insecticide dosage on glass as on nettings. Mortality data were either 0 or 100% for most concentrations except for a narrow range. MKDT was log linear function of total deltamethrin content in a commercial polyethylene net exposed to washings. The regeneration time of this net increased with the number of washes and MKDT became higher. A new, easy and rapid method to determine MKDT is suggested. Discussion The MKDT is ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 7 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Pigeon Olivier Bonnet Julien Skovmand Ole Corbel Vincent Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Insecticide treated bed nets are major tools for the Roll Back Malaria campaign. There are two types of Long-Lasting Insecticide-treated Nets (LNs) on the market: coated nets and insecticide-incorporated nets. Nets provided to this market need a recommendation from the World Health Organization to be purchased by donors and NGOs. During laboratory study (phase I), the first step consists in evaluating the wash resistance of a new LN product. When insecticide-incorporated nets are washed, it takes time to regenerate the insecticidal activity, i.e. insecticide must migrate to the net surface to be accessible to mosquitoes. The interval of time required for regeneration must be carefully determined to ensure the accuracy of further results. WHOPES procedures currently recommend the determination of the regeneration time by using mortality data. However, as mortality cannot exceed 100%, a LN that regenerates a surface concentration exceeding the dosage for 100% mortality, will have its regeneration time underestimated. Methods The Median Knock Down Time (MKDT) was determined as function of insecticide dosage on an inert surface, glass, and on polyester nettings using an acetone solution or a simple emulsion. Dosage response was also established for mortality data. The same method was then applied to a commercially polyethylene netting, currently under WHOPES evaluation, to determine the dynamics of regeneration as function of repeated washings. The deltamethrin content of these nets was estimated by Capillary Gas Chromatography (GC-ECD). Results MKDT was a linear function of log insecticide dosage on glass as on nettings. Mortality data were either 0 or 100% for most concentrations except for a narrow range. MKDT was log linear function of total deltamethrin content in a commercial polyethylene net exposed to washings. The regeneration time of this net increased with the number of washes and MKDT became higher. A new, easy and rapid method to determine MKDT is suggested. Discussion The MKDT is ... |
format |
Article in Journal/Newspaper |
author |
Pigeon Olivier Bonnet Julien Skovmand Ole Corbel Vincent |
author_facet |
Pigeon Olivier Bonnet Julien Skovmand Ole Corbel Vincent |
author_sort |
Pigeon Olivier |
title |
Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
title_short |
Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
title_full |
Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
title_fullStr |
Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
title_full_unstemmed |
Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
title_sort |
median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control |
publisher |
BMC |
publishDate |
2008 |
url |
https://doi.org/10.1186/1475-2875-7-114 https://doaj.org/article/91a43a54d8a04d828c7a4bb746137196 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 7, Iss 1, p 114 (2008) |
op_relation |
http://www.malariajournal.com/content/7/1/114 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-7-114 1475-2875 https://doaj.org/article/91a43a54d8a04d828c7a4bb746137196 |
op_doi |
https://doi.org/10.1186/1475-2875-7-114 |
container_title |
Malaria Journal |
container_volume |
7 |
container_issue |
1 |
_version_ |
1766346021095342080 |