Neurobrucellosis in children
Neurobrucellosis is a complication of brucellosis, which is considered endemic in the Indian subcontinent, Arabian Peninsula and Mediterranean countries. Brucella reaches the central nervous system via hematogenous spread in the infected human being, or through phagocytosis. Neurobrucellosis can pre...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2015
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Online Access: | https://doi.org/10.1016/S2221-1691(15)30160-X https://doaj.org/article/90c58a3e5e6a4eb7b98c3b69d3570cd5 |
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ftdoajarticles:oai:doaj.org/article:90c58a3e5e6a4eb7b98c3b69d3570cd5 2023-05-15T15:03:06+02:00 Neurobrucellosis in children Mohamed Ata Hendaus Rasha Muneer Qaqish Ahmed Hassan Alhammadi 2015-02-01T00:00:00Z https://doi.org/10.1016/S2221-1691(15)30160-X https://doaj.org/article/90c58a3e5e6a4eb7b98c3b69d3570cd5 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S222116911530160X https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30160-X https://doaj.org/article/90c58a3e5e6a4eb7b98c3b69d3570cd5 Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 2, Pp 158-161 (2015) Children Brucella Neuro Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2015 ftdoajarticles https://doi.org/10.1016/S2221-1691(15)30160-X 2022-12-31T13:32:21Z Neurobrucellosis is a complication of brucellosis, which is considered endemic in the Indian subcontinent, Arabian Peninsula and Mediterranean countries. Brucella reaches the central nervous system via hematogenous spread in the infected human being, or through phagocytosis. Neurobrucellosis can present with any neurological symptoms, hence, the index of suspicion must be high enough to make proper diagnosis. Cerebrospinal fluid studies are usually diagnostic, while imagings including magnetic resonance imaging and computed tomography are of little assistance. As for therapy, a combination of antibiotics must be administered with a goal to reduce relapse or avoid failure. The duration of treatment should be tailored as per clinical signs and symptoms until the cerebrospinal fluid components return to normal, which might be up to six months. In this article, we present an overall view of current understanding of neurobrucellosis in children, its epidemiology, clinical features, diagnostic tests, and management options. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Indian Asian Pacific Journal of Tropical Biomedicine 5 2 158 161 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Children Brucella Neuro Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Children Brucella Neuro Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Mohamed Ata Hendaus Rasha Muneer Qaqish Ahmed Hassan Alhammadi Neurobrucellosis in children |
topic_facet |
Children Brucella Neuro Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Neurobrucellosis is a complication of brucellosis, which is considered endemic in the Indian subcontinent, Arabian Peninsula and Mediterranean countries. Brucella reaches the central nervous system via hematogenous spread in the infected human being, or through phagocytosis. Neurobrucellosis can present with any neurological symptoms, hence, the index of suspicion must be high enough to make proper diagnosis. Cerebrospinal fluid studies are usually diagnostic, while imagings including magnetic resonance imaging and computed tomography are of little assistance. As for therapy, a combination of antibiotics must be administered with a goal to reduce relapse or avoid failure. The duration of treatment should be tailored as per clinical signs and symptoms until the cerebrospinal fluid components return to normal, which might be up to six months. In this article, we present an overall view of current understanding of neurobrucellosis in children, its epidemiology, clinical features, diagnostic tests, and management options. |
format |
Article in Journal/Newspaper |
author |
Mohamed Ata Hendaus Rasha Muneer Qaqish Ahmed Hassan Alhammadi |
author_facet |
Mohamed Ata Hendaus Rasha Muneer Qaqish Ahmed Hassan Alhammadi |
author_sort |
Mohamed Ata Hendaus |
title |
Neurobrucellosis in children |
title_short |
Neurobrucellosis in children |
title_full |
Neurobrucellosis in children |
title_fullStr |
Neurobrucellosis in children |
title_full_unstemmed |
Neurobrucellosis in children |
title_sort |
neurobrucellosis in children |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2015 |
url |
https://doi.org/10.1016/S2221-1691(15)30160-X https://doaj.org/article/90c58a3e5e6a4eb7b98c3b69d3570cd5 |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 2, Pp 158-161 (2015) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S222116911530160X https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30160-X https://doaj.org/article/90c58a3e5e6a4eb7b98c3b69d3570cd5 |
op_doi |
https://doi.org/10.1016/S2221-1691(15)30160-X |
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Asian Pacific Journal of Tropical Biomedicine |
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5 |
container_issue |
2 |
container_start_page |
158 |
op_container_end_page |
161 |
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1766335011401760768 |