Difference in tissue temperature change between two cryoballoons
Background Cryoballoon ablation, especially Arctic Front Advance Pro (AFA-Pro) (Medtronic, Minneapolis, Minnesota, USA), has been widely recognised as a standard approach to atrial fibrillation (AF). Recently, Boston Scientific has released a novel cryoballoon system (POLARx). Despite comparable acu...
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ftdoajarticles:oai:doaj.org/article:902044f4dcd2452a878015a20b888861 2024-02-04T09:58:21+01:00 Difference in tissue temperature change between two cryoballoons Shigeru Saito Masato Murakami Takahiro Hayashi Kiyotaka Iwasaki Kohei Hamada Jumpei Takada 2023-11-01T00:00:00Z https://doi.org/10.1136/openhrt-2023-002426 https://doaj.org/article/902044f4dcd2452a878015a20b888861 EN eng BMJ Publishing Group https://openheart.bmj.com/content/10/2/e002426.full https://doaj.org/toc/2053-3624 doi:10.1136/openhrt-2023-002426 2053-3624 https://doaj.org/article/902044f4dcd2452a878015a20b888861 Open Heart, Vol 10, Iss 2 (2023) Diseases of the circulatory (Cardiovascular) system RC666-701 article 2023 ftdoajarticles https://doi.org/10.1136/openhrt-2023-002426 2024-01-07T01:41:43Z Background Cryoballoon ablation, especially Arctic Front Advance Pro (AFA-Pro) (Medtronic, Minneapolis, Minnesota, USA), has been widely recognised as a standard approach to atrial fibrillation (AF). Recently, Boston Scientific has released a novel cryoballoon system (POLARx). Despite comparable acute clinical outcomes of these two cryoballoons, the recent study reported a higher complication rate, especially for phrenic nerve palsy, with POLARx. However, their impact on biological tissue remains unclear.Objective The purpose of our study is to evaluate temperature change of biological tissue during cryoablation of each cryoballoon using a porcine experimental model.Method A tissue-based pulmonary vein model was constructed from porcine myocardial tissue and placed on a stage designed to simulate pulmonary vein anatomy and venous flow. Controlled cryoablations of AFA-Pro and POLARx were performed in this model to evaluate the tissue temperature. A temperature sensor was set behind the muscle and cryoballoon ablation was performed after confirming the occlusion of pulmonary vein with cryoballoon.Results The mean tissue nadir temperature during cryoablation with AFA-Pro was −41.5°C±4.9°C, while the mean tissue nadir temperature during cryoablation with POLARx was −58.4°C±5.9°C (p<0.001). The mean balloon nadir temperature during cryoablation with AFA-Pro was −54.6°C±2.6°C and the mean balloon nadir temperature during cryoablation with POLARx was −64.7°C±3.8°C (p<0.001).Conclusion POLARx could freeze the biological tissue more strongly than AFA-Pro. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Open Heart 10 2 e002426 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Diseases of the circulatory (Cardiovascular) system RC666-701 |
spellingShingle |
Diseases of the circulatory (Cardiovascular) system RC666-701 Shigeru Saito Masato Murakami Takahiro Hayashi Kiyotaka Iwasaki Kohei Hamada Jumpei Takada Difference in tissue temperature change between two cryoballoons |
topic_facet |
Diseases of the circulatory (Cardiovascular) system RC666-701 |
description |
Background Cryoballoon ablation, especially Arctic Front Advance Pro (AFA-Pro) (Medtronic, Minneapolis, Minnesota, USA), has been widely recognised as a standard approach to atrial fibrillation (AF). Recently, Boston Scientific has released a novel cryoballoon system (POLARx). Despite comparable acute clinical outcomes of these two cryoballoons, the recent study reported a higher complication rate, especially for phrenic nerve palsy, with POLARx. However, their impact on biological tissue remains unclear.Objective The purpose of our study is to evaluate temperature change of biological tissue during cryoablation of each cryoballoon using a porcine experimental model.Method A tissue-based pulmonary vein model was constructed from porcine myocardial tissue and placed on a stage designed to simulate pulmonary vein anatomy and venous flow. Controlled cryoablations of AFA-Pro and POLARx were performed in this model to evaluate the tissue temperature. A temperature sensor was set behind the muscle and cryoballoon ablation was performed after confirming the occlusion of pulmonary vein with cryoballoon.Results The mean tissue nadir temperature during cryoablation with AFA-Pro was −41.5°C±4.9°C, while the mean tissue nadir temperature during cryoablation with POLARx was −58.4°C±5.9°C (p<0.001). The mean balloon nadir temperature during cryoablation with AFA-Pro was −54.6°C±2.6°C and the mean balloon nadir temperature during cryoablation with POLARx was −64.7°C±3.8°C (p<0.001).Conclusion POLARx could freeze the biological tissue more strongly than AFA-Pro. |
format |
Article in Journal/Newspaper |
author |
Shigeru Saito Masato Murakami Takahiro Hayashi Kiyotaka Iwasaki Kohei Hamada Jumpei Takada |
author_facet |
Shigeru Saito Masato Murakami Takahiro Hayashi Kiyotaka Iwasaki Kohei Hamada Jumpei Takada |
author_sort |
Shigeru Saito |
title |
Difference in tissue temperature change between two cryoballoons |
title_short |
Difference in tissue temperature change between two cryoballoons |
title_full |
Difference in tissue temperature change between two cryoballoons |
title_fullStr |
Difference in tissue temperature change between two cryoballoons |
title_full_unstemmed |
Difference in tissue temperature change between two cryoballoons |
title_sort |
difference in tissue temperature change between two cryoballoons |
publisher |
BMJ Publishing Group |
publishDate |
2023 |
url |
https://doi.org/10.1136/openhrt-2023-002426 https://doaj.org/article/902044f4dcd2452a878015a20b888861 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Open Heart, Vol 10, Iss 2 (2023) |
op_relation |
https://openheart.bmj.com/content/10/2/e002426.full https://doaj.org/toc/2053-3624 doi:10.1136/openhrt-2023-002426 2053-3624 https://doaj.org/article/902044f4dcd2452a878015a20b888861 |
op_doi |
https://doi.org/10.1136/openhrt-2023-002426 |
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Open Heart |
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10 |
container_issue |
2 |
container_start_page |
e002426 |
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