Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea
Abstract Background Countries in the Southeast Asia region have a high prevalence of soil-transmitted helminth, such as roundworm, whipworm, and hookworms [Ancylostoma duodenale, Necator americanus, Ancylostoma ceylanicum]. Recent molecular-based surveys have revealed that A. ceylanicum, a zoonotic...
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ftdoajarticles:oai:doaj.org/article:901897fd87eb4b3798b3644d76f18142 2023-05-15T15:18:14+02:00 Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea Masahide Yoshikawa Yukiteru Ouji Nobuyasu Hirai Fukumi Nakamura-Uchiyama Minoru Yamada Naoki Arizono Naoaki Akamatsu Takaharu Yoh Daisuke Kaya Toshiya Nakatani Eiryo Kikuchi Yuichi Katanami Kimitoshi Satoh Ryosuke Maki Yusuke Miyazato Yuichiro Oba Kei Kasahara Keiichi Mikasa 2018-03-01T00:00:00Z https://doi.org/10.1186/s41182-018-0087-8 https://doaj.org/article/901897fd87eb4b3798b3644d76f18142 EN eng BMC http://link.springer.com/article/10.1186/s41182-018-0087-8 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-018-0087-8 1349-4147 https://doaj.org/article/901897fd87eb4b3798b3644d76f18142 Tropical Medicine and Health, Vol 46, Iss 1, Pp 1-6 (2018) Ancylostoma ceylanicum Soil-transmitted helminth Imported parasitosis Southeast Asia Papua New Guinea Traveler’s diarrhea Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.1186/s41182-018-0087-8 2022-12-31T12:17:47Z Abstract Background Countries in the Southeast Asia region have a high prevalence of soil-transmitted helminth, such as roundworm, whipworm, and hookworms [Ancylostoma duodenale, Necator americanus, Ancylostoma ceylanicum]. Recent molecular-based surveys have revealed that A. ceylanicum, a zoonotic hookworm, is likely the second most prevalent hookworm species infecting humans in that part of the world, while others have noted that this infection is an emerging public health risk not only for indigenous people but also for visitors from other countries. Case presentation We recently encountered four cases of A. ceylanicum infection in Japanese individuals who returned from Southeast Asia and Papua New Guinea. Case 1 was a 25-year-old male who stayed in a rainforest in Malaysia for 4 weeks, where he developed abdominal pain and diarrhea in the third week. Eleven adult worms (five males, six females) were expelled after treatment with pyrantel pamoate and identified as A. ceylanicum based on morphological characteristics and DNA sequences of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Case 2 was a 26-year-old male who spent 2 years as an overseas cooperation volunteer for agriculture in Papua New Guinea. He did not note any symptoms at that time, though eggs were detected in feces samples at a medical check-up examination after returning. Although collection of adult worms was unsuccessful, DNA analysis of the eggs for cox1 and the ribosomal internal transcribed spacer (ITS)-1 and ITS-2 genes demonstrated that they were A. ceylanicum. Case 3 was a 47-year-old male who spent 1 month in a rural village in Lao People’s Democratic Republic and began suffering from watery diarrhea from the third week. A total of nine adult worms (three males, six females) were collected by endoscopic procedures and following treatment with pyrantel pamoate. Morphological examination and molecular analyses of the cox1 gene showed that they were A. ceylanicum. Case 4 was a 27-year-old male who participated in group ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 46 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Ancylostoma ceylanicum Soil-transmitted helminth Imported parasitosis Southeast Asia Papua New Guinea Traveler’s diarrhea Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Ancylostoma ceylanicum Soil-transmitted helminth Imported parasitosis Southeast Asia Papua New Guinea Traveler’s diarrhea Arctic medicine. Tropical medicine RC955-962 Masahide Yoshikawa Yukiteru Ouji Nobuyasu Hirai Fukumi Nakamura-Uchiyama Minoru Yamada Naoki Arizono Naoaki Akamatsu Takaharu Yoh Daisuke Kaya Toshiya Nakatani Eiryo Kikuchi Yuichi Katanami Kimitoshi Satoh Ryosuke Maki Yusuke Miyazato Yuichiro Oba Kei Kasahara Keiichi Mikasa Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
topic_facet |
Ancylostoma ceylanicum Soil-transmitted helminth Imported parasitosis Southeast Asia Papua New Guinea Traveler’s diarrhea Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Countries in the Southeast Asia region have a high prevalence of soil-transmitted helminth, such as roundworm, whipworm, and hookworms [Ancylostoma duodenale, Necator americanus, Ancylostoma ceylanicum]. Recent molecular-based surveys have revealed that A. ceylanicum, a zoonotic hookworm, is likely the second most prevalent hookworm species infecting humans in that part of the world, while others have noted that this infection is an emerging public health risk not only for indigenous people but also for visitors from other countries. Case presentation We recently encountered four cases of A. ceylanicum infection in Japanese individuals who returned from Southeast Asia and Papua New Guinea. Case 1 was a 25-year-old male who stayed in a rainforest in Malaysia for 4 weeks, where he developed abdominal pain and diarrhea in the third week. Eleven adult worms (five males, six females) were expelled after treatment with pyrantel pamoate and identified as A. ceylanicum based on morphological characteristics and DNA sequences of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Case 2 was a 26-year-old male who spent 2 years as an overseas cooperation volunteer for agriculture in Papua New Guinea. He did not note any symptoms at that time, though eggs were detected in feces samples at a medical check-up examination after returning. Although collection of adult worms was unsuccessful, DNA analysis of the eggs for cox1 and the ribosomal internal transcribed spacer (ITS)-1 and ITS-2 genes demonstrated that they were A. ceylanicum. Case 3 was a 47-year-old male who spent 1 month in a rural village in Lao People’s Democratic Republic and began suffering from watery diarrhea from the third week. A total of nine adult worms (three males, six females) were collected by endoscopic procedures and following treatment with pyrantel pamoate. Morphological examination and molecular analyses of the cox1 gene showed that they were A. ceylanicum. Case 4 was a 27-year-old male who participated in group ... |
format |
Article in Journal/Newspaper |
author |
Masahide Yoshikawa Yukiteru Ouji Nobuyasu Hirai Fukumi Nakamura-Uchiyama Minoru Yamada Naoki Arizono Naoaki Akamatsu Takaharu Yoh Daisuke Kaya Toshiya Nakatani Eiryo Kikuchi Yuichi Katanami Kimitoshi Satoh Ryosuke Maki Yusuke Miyazato Yuichiro Oba Kei Kasahara Keiichi Mikasa |
author_facet |
Masahide Yoshikawa Yukiteru Ouji Nobuyasu Hirai Fukumi Nakamura-Uchiyama Minoru Yamada Naoki Arizono Naoaki Akamatsu Takaharu Yoh Daisuke Kaya Toshiya Nakatani Eiryo Kikuchi Yuichi Katanami Kimitoshi Satoh Ryosuke Maki Yusuke Miyazato Yuichiro Oba Kei Kasahara Keiichi Mikasa |
author_sort |
Masahide Yoshikawa |
title |
Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
title_short |
Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
title_full |
Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
title_fullStr |
Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
title_full_unstemmed |
Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea |
title_sort |
ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four japanese patients who returned from southeast asia and papua new guinea |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s41182-018-0087-8 https://doaj.org/article/901897fd87eb4b3798b3644d76f18142 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 46, Iss 1, Pp 1-6 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s41182-018-0087-8 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-018-0087-8 1349-4147 https://doaj.org/article/901897fd87eb4b3798b3644d76f18142 |
op_doi |
https://doi.org/10.1186/s41182-018-0087-8 |
container_title |
Tropical Medicine and Health |
container_volume |
46 |
container_issue |
1 |
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1766348454093651968 |