Isolation and structural elucidation of cytotoxic compounds from the root bark of Diospyros quercina (Baill.) endemic to Madagascar

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Authors: Fatiany Pierre Ruphin, Robijaona Baholy, Randrianarivo Emmanuel, Raharisololalao Amelie, Marie-Therese Martin, Ngbolua Koto–te-Nyiwa
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014
• Subjects: Diospyros quercinia; Cytotoxic activities; Isodiospyrin; 6′-Ethoxy-1′; 3′-dihydroxy-4; 6-dimethyl-1,2′-binaphthyl-2,5′,8,8′tetraones; (E)-5,6-Dimethyl-2-(2-methyl-3-(prop-1-enyl) phenyl)-2H-Chromene; Madagascar; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic; Lowry
• Online Access: https://doi.org/10.1016/S2221-1691(14)60227-6; https://doaj.org/article/8f76845b11e34768864f55c7cd0ba6f7

Objective: To isolate and characterize the cytotoxic compounds from Diospyros quercina (Baill.) G.E. Schatz & Lowry (Ebenaceae). Methods: An ethno-botanical survey was conducted in the south of Madagascar from July to August 2010. Bio-guided fractionation assay was carried out on the root bark o...