Estimating the infection burden of COVID-19 in Malaysia.
Malaysia has reported 2.75 million cases and 31,485 deaths as of 30 December 2021. Underestimation remains an issue due to the underdiagnosis of mild and asymptomatic cases. We aimed to estimate the burden of COVID-19 cases in Malaysia based on an adjusted case fatality rate (aCFR). Data on reported...
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ftdoajarticles:oai:doaj.org/article:8f30de6e15264d61aa94748dc58fac63 2023-10-09T21:49:14+02:00 Estimating the infection burden of COVID-19 in Malaysia. Vivek Jason Jayaraj Chiu-Wan Ng Awang Bulgiba Maheshwara Rao Appannan Sanjay Rampal 2022-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0010887 https://doaj.org/article/8f30de6e15264d61aa94748dc58fac63 EN eng Public Library of Science (PLoS) https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010887&type=printable https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010887 https://doaj.org/article/8f30de6e15264d61aa94748dc58fac63 PLoS Neglected Tropical Diseases, Vol 16, Iss 11, p e0010887 (2022) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles https://doi.org/10.1371/journal.pntd.0010887 2023-09-24T00:39:40Z Malaysia has reported 2.75 million cases and 31,485 deaths as of 30 December 2021. Underestimation remains an issue due to the underdiagnosis of mild and asymptomatic cases. We aimed to estimate the burden of COVID-19 cases in Malaysia based on an adjusted case fatality rate (aCFR). Data on reported cases and mortalities were collated from the Ministry of Health official GitHub between 1 March 2020 and 30 December 2021. We estimated the total and age-stratified monthly incidence rates, mortality rates, and aCFR. Estimated new infections were inferred from the age-stratified aCFR. The total estimated infections between 1 March 2020 and 30 December 2021 was 9,955,000-cases (95% CI: 6,626,000-18,985,000). The proportion of COVID-19 infections in ages 0-11, 12-17, 18-50, 51-65, and above 65 years were 19.9% (n = 1,982,000), 2.4% (n = 236,000), 66.1% (n = 6,577,000), 9.1% (n = 901,000), 2.6% (n = 256,000), respectively. Approximately 32.8% of the total population in Malaysia was estimated to have been infected with COVID-19 by the end of December 2021. These estimations highlight a more accurate infection burden in Malaysia. It provides the first national-level prevalence estimates in Malaysia that adjusted for underdiagnosis. Naturally acquired community immunity has increased, but approximately 68.1% of the population remains susceptible. Population estimates of the infection burden are critical to determine the need for booster doses and calibration of public health measures. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 16 11 e0010887 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Vivek Jason Jayaraj Chiu-Wan Ng Awang Bulgiba Maheshwara Rao Appannan Sanjay Rampal Estimating the infection burden of COVID-19 in Malaysia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Malaysia has reported 2.75 million cases and 31,485 deaths as of 30 December 2021. Underestimation remains an issue due to the underdiagnosis of mild and asymptomatic cases. We aimed to estimate the burden of COVID-19 cases in Malaysia based on an adjusted case fatality rate (aCFR). Data on reported cases and mortalities were collated from the Ministry of Health official GitHub between 1 March 2020 and 30 December 2021. We estimated the total and age-stratified monthly incidence rates, mortality rates, and aCFR. Estimated new infections were inferred from the age-stratified aCFR. The total estimated infections between 1 March 2020 and 30 December 2021 was 9,955,000-cases (95% CI: 6,626,000-18,985,000). The proportion of COVID-19 infections in ages 0-11, 12-17, 18-50, 51-65, and above 65 years were 19.9% (n = 1,982,000), 2.4% (n = 236,000), 66.1% (n = 6,577,000), 9.1% (n = 901,000), 2.6% (n = 256,000), respectively. Approximately 32.8% of the total population in Malaysia was estimated to have been infected with COVID-19 by the end of December 2021. These estimations highlight a more accurate infection burden in Malaysia. It provides the first national-level prevalence estimates in Malaysia that adjusted for underdiagnosis. Naturally acquired community immunity has increased, but approximately 68.1% of the population remains susceptible. Population estimates of the infection burden are critical to determine the need for booster doses and calibration of public health measures. |
format |
Article in Journal/Newspaper |
author |
Vivek Jason Jayaraj Chiu-Wan Ng Awang Bulgiba Maheshwara Rao Appannan Sanjay Rampal |
author_facet |
Vivek Jason Jayaraj Chiu-Wan Ng Awang Bulgiba Maheshwara Rao Appannan Sanjay Rampal |
author_sort |
Vivek Jason Jayaraj |
title |
Estimating the infection burden of COVID-19 in Malaysia. |
title_short |
Estimating the infection burden of COVID-19 in Malaysia. |
title_full |
Estimating the infection burden of COVID-19 in Malaysia. |
title_fullStr |
Estimating the infection burden of COVID-19 in Malaysia. |
title_full_unstemmed |
Estimating the infection burden of COVID-19 in Malaysia. |
title_sort |
estimating the infection burden of covid-19 in malaysia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2022 |
url |
https://doi.org/10.1371/journal.pntd.0010887 https://doaj.org/article/8f30de6e15264d61aa94748dc58fac63 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 16, Iss 11, p e0010887 (2022) |
op_relation |
https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010887&type=printable https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010887 https://doaj.org/article/8f30de6e15264d61aa94748dc58fac63 |
op_doi |
https://doi.org/10.1371/journal.pntd.0010887 |
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PLOS Neglected Tropical Diseases |
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16 |
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11 |
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e0010887 |
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