Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil
This study aims to perform the first molecular and clinical-epidemiological analysis of dengue cases in Divinopolis, MG, Brazil. Data from 4,110 cases of dengue were accessed and 190 clinical samples were collected for molecular analyses. In this study, 2.7% of the men and 3.0% of the women were adm...
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ftdoajarticles:oai:doaj.org/article:8ed0e7fe60b646d788cfd45f8b5fd6a3 2023-05-15T15:08:49+02:00 Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil Juliana Cristina Duarte Braga Leandro César da Silva Jacqueline Domingues Tibúrcio Mirna de Abreu e Silva Lailah Horácio Sales Pereira Karina Rocha Dutra Jaqueline Maria Siqueira Ferreira Débora de Oliveira Lopes Luciana Lara dos Santos 2014-01-01T00:00:00Z https://doi.org/10.1155/2014/276912 https://doaj.org/article/8ed0e7fe60b646d788cfd45f8b5fd6a3 EN eng Hindawi Limited http://dx.doi.org/10.1155/2014/276912 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2014/276912 https://doaj.org/article/8ed0e7fe60b646d788cfd45f8b5fd6a3 Journal of Tropical Medicine, Vol 2014 (2014) Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1155/2014/276912 2022-12-30T21:47:32Z This study aims to perform the first molecular and clinical-epidemiological analysis of dengue cases in Divinopolis, MG, Brazil. Data from 4,110 cases of dengue were accessed and 190 clinical samples were collected for molecular analyses. In this study, 2.7% of the men and 3.0% of the women were admitted to hospital. There was no association between gender and hospital admission. The symptoms observed in this study are according to the Health Ministry, but fever was present in 82.2% and not in 100% of cases. The chance of hospital admission was 1.55 higher in patients with any kind of bleeding (334) and 2.4% of individuals without bleeding were also hospitalized due to other warning signs. In the molecular analyses, 23% of the samples were positive for DENV. DENV-2 and DENV-3 were identified in 2010, DENV-3 in 2011, DENV-1 in 2012, and DENV-1 and DENV-4 in 2013. DENV detection was possible in samples with only one day of symptoms. This first report of dengue data in Divinópolis provided more insight into the viral types and effects of disease in the city, confirming the need for caution in assessing cases of suspected dengue and for revision of the criteria proposed by the Health Ministry to classify cases of the disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2014 1 6 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Juliana Cristina Duarte Braga Leandro César da Silva Jacqueline Domingues Tibúrcio Mirna de Abreu e Silva Lailah Horácio Sales Pereira Karina Rocha Dutra Jaqueline Maria Siqueira Ferreira Débora de Oliveira Lopes Luciana Lara dos Santos Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
This study aims to perform the first molecular and clinical-epidemiological analysis of dengue cases in Divinopolis, MG, Brazil. Data from 4,110 cases of dengue were accessed and 190 clinical samples were collected for molecular analyses. In this study, 2.7% of the men and 3.0% of the women were admitted to hospital. There was no association between gender and hospital admission. The symptoms observed in this study are according to the Health Ministry, but fever was present in 82.2% and not in 100% of cases. The chance of hospital admission was 1.55 higher in patients with any kind of bleeding (334) and 2.4% of individuals without bleeding were also hospitalized due to other warning signs. In the molecular analyses, 23% of the samples were positive for DENV. DENV-2 and DENV-3 were identified in 2010, DENV-3 in 2011, DENV-1 in 2012, and DENV-1 and DENV-4 in 2013. DENV detection was possible in samples with only one day of symptoms. This first report of dengue data in Divinópolis provided more insight into the viral types and effects of disease in the city, confirming the need for caution in assessing cases of suspected dengue and for revision of the criteria proposed by the Health Ministry to classify cases of the disease. |
format |
Article in Journal/Newspaper |
author |
Juliana Cristina Duarte Braga Leandro César da Silva Jacqueline Domingues Tibúrcio Mirna de Abreu e Silva Lailah Horácio Sales Pereira Karina Rocha Dutra Jaqueline Maria Siqueira Ferreira Débora de Oliveira Lopes Luciana Lara dos Santos |
author_facet |
Juliana Cristina Duarte Braga Leandro César da Silva Jacqueline Domingues Tibúrcio Mirna de Abreu e Silva Lailah Horácio Sales Pereira Karina Rocha Dutra Jaqueline Maria Siqueira Ferreira Débora de Oliveira Lopes Luciana Lara dos Santos |
author_sort |
Juliana Cristina Duarte Braga |
title |
Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
title_short |
Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
title_full |
Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
title_fullStr |
Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
title_full_unstemmed |
Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil |
title_sort |
clinical, molecular, and epidemiological analysis of dengue cases during a major outbreak in the midwest region of minas gerais, brazil |
publisher |
Hindawi Limited |
publishDate |
2014 |
url |
https://doi.org/10.1155/2014/276912 https://doaj.org/article/8ed0e7fe60b646d788cfd45f8b5fd6a3 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2014 (2014) |
op_relation |
http://dx.doi.org/10.1155/2014/276912 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2014/276912 https://doaj.org/article/8ed0e7fe60b646d788cfd45f8b5fd6a3 |
op_doi |
https://doi.org/10.1155/2014/276912 |
container_title |
Journal of Tropical Medicine |
container_volume |
2014 |
container_start_page |
1 |
op_container_end_page |
6 |
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1766340105870508032 |