The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia
Introduction Although the initiation of highly active antiretroviral therapy (HAART) is accompanied by an attenuation of viral load, metabolic disorders characterized by hyperglycemia, dyslipidemia, and lipodystrophy are often observed in patients under this treatment. Certain foods, such as oat bra...
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ftdoajarticles:oai:doaj.org/article:8e3bae2e873a44e89536d04e4d449b87 2023-05-15T15:11:15+02:00 The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia Rosangela dos Santos Ferreira Daiane Colman Cassaro Hamilton Domingos Elenir Rose Jardim Cury Pontes Priscila Hiane Aiko Junia Elisa Carvalho de Meira 2013-12-01T00:00:00Z https://doi.org/10.1590/0037-8682-0087-2013 https://doaj.org/article/8e3bae2e873a44e89536d04e4d449b87 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600691&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0087-2013 https://doaj.org/article/8e3bae2e873a44e89536d04e4d449b87 Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 6, Pp 691-697 (2013) HIV/AIDS serodiagnosis AIDS Dyslipidemia Hyperuricemia Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles https://doi.org/10.1590/0037-8682-0087-2013 2022-12-30T23:17:40Z Introduction Although the initiation of highly active antiretroviral therapy (HAART) is accompanied by an attenuation of viral load, metabolic disorders characterized by hyperglycemia, dyslipidemia, and lipodystrophy are often observed in patients under this treatment. Certain foods, such as oat bran, soy protein, and flaxseed, have been shown to improve a patient's lipid profile despite possible increases in uricemia. Thus, a bioactive compound was formulated using these foods to help patients with HIV/AIDS control metabolic disorders resulting from HAART. Methods An uncontrolled before and after study was performed. The total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, and uric acid before and after 3 months of consuming the formulation were compared in patients. The compound was formulated such that 40g (the recommended daily intake) contained approximately 10g of flaxseed, 20g of oat bran, and 10g of textured soy protein. Results The study population consisted of 139 patients, 31 of whom were included in the final analysis. There were no significant variations between the laboratory results obtained before and after consumption of the compound. Conclusions The regular consumption of the formulation together with individualized dietary guidance did not reduce lipid levels and did not contribute to an increase in uricemia in the study group. However, new studies with higher doses of the foods that compose the formulation should be encouraged to investigate whether these foods can positively influence the lipid profiles of these patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 46 6 691 697 |
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ftdoajarticles |
language |
English |
topic |
HIV/AIDS serodiagnosis AIDS Dyslipidemia Hyperuricemia Arctic medicine. Tropical medicine RC955-962 |
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HIV/AIDS serodiagnosis AIDS Dyslipidemia Hyperuricemia Arctic medicine. Tropical medicine RC955-962 Rosangela dos Santos Ferreira Daiane Colman Cassaro Hamilton Domingos Elenir Rose Jardim Cury Pontes Priscila Hiane Aiko Junia Elisa Carvalho de Meira The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
topic_facet |
HIV/AIDS serodiagnosis AIDS Dyslipidemia Hyperuricemia Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction Although the initiation of highly active antiretroviral therapy (HAART) is accompanied by an attenuation of viral load, metabolic disorders characterized by hyperglycemia, dyslipidemia, and lipodystrophy are often observed in patients under this treatment. Certain foods, such as oat bran, soy protein, and flaxseed, have been shown to improve a patient's lipid profile despite possible increases in uricemia. Thus, a bioactive compound was formulated using these foods to help patients with HIV/AIDS control metabolic disorders resulting from HAART. Methods An uncontrolled before and after study was performed. The total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, and uric acid before and after 3 months of consuming the formulation were compared in patients. The compound was formulated such that 40g (the recommended daily intake) contained approximately 10g of flaxseed, 20g of oat bran, and 10g of textured soy protein. Results The study population consisted of 139 patients, 31 of whom were included in the final analysis. There were no significant variations between the laboratory results obtained before and after consumption of the compound. Conclusions The regular consumption of the formulation together with individualized dietary guidance did not reduce lipid levels and did not contribute to an increase in uricemia in the study group. However, new studies with higher doses of the foods that compose the formulation should be encouraged to investigate whether these foods can positively influence the lipid profiles of these patients. |
format |
Article in Journal/Newspaper |
author |
Rosangela dos Santos Ferreira Daiane Colman Cassaro Hamilton Domingos Elenir Rose Jardim Cury Pontes Priscila Hiane Aiko Junia Elisa Carvalho de Meira |
author_facet |
Rosangela dos Santos Ferreira Daiane Colman Cassaro Hamilton Domingos Elenir Rose Jardim Cury Pontes Priscila Hiane Aiko Junia Elisa Carvalho de Meira |
author_sort |
Rosangela dos Santos Ferreira |
title |
The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
title_short |
The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
title_full |
The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
title_fullStr |
The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
title_full_unstemmed |
The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia |
title_sort |
effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with aids and dyslipidemia |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2013 |
url |
https://doi.org/10.1590/0037-8682-0087-2013 https://doaj.org/article/8e3bae2e873a44e89536d04e4d449b87 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 6, Pp 691-697 (2013) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600691&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0087-2013 https://doaj.org/article/8e3bae2e873a44e89536d04e4d449b87 |
op_doi |
https://doi.org/10.1590/0037-8682-0087-2013 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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46 |
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