Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management
Abstract Background Malaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis and treatment of malaria cases and intermittent preventive treatment in pregnancy (IPTp), vector control is an important tool in the reduction of new cases. A...
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ftdoajarticles:oai:doaj.org/article:8d2575125bd84c39b4ec2854b71b3992 2023-05-15T15:12:28+02:00 Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management Peter Dambach Till Baernighausen Issouf Traoré Saidou Ouedraogo Ali Sié Rainer Sauerborn Norbert Becker Valérie R. Louis 2019-09-01T00:00:00Z https://doi.org/10.1186/s12936-019-2951-3 https://doaj.org/article/8d2575125bd84c39b4ec2854b71b3992 EN eng BMC http://link.springer.com/article/10.1186/s12936-019-2951-3 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2951-3 1475-2875 https://doaj.org/article/8d2575125bd84c39b4ec2854b71b3992 Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019) Bacillus thuringiensis israelensis Vector control Anopheles Larval source management Burkina Faso Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2019 ftdoajarticles https://doi.org/10.1186/s12936-019-2951-3 2022-12-31T02:41:12Z Abstract Background Malaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis and treatment of malaria cases and intermittent preventive treatment in pregnancy (IPTp), vector control is an important tool in the reduction of new cases. Alongside the use of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), targeting the vector larvae with biological larvicides, such as Bacillus thuringiensis israelensis (Bti) is gaining importance as a means of reducing the number of mosquito larvae before they emerge to their adult stage. This study presents data corroborating the entomological impact of such an intervention in a rural African environment. Methods The study extended over 2 years and researched the impact of biological larviciding with Bti on malaria mosquitoes that were caught indoors and outdoors of houses using light traps. The achieved reductions in female Anopheles mosquitoes were calculated for two different larviciding choices using a regression model. Results In villages that received selective treatment of the most productive breeding sites, the number of female Anopheles spp. dropped by 61% (95% CI 54–66%) compared to the pre-intervention period. In villages in which all breeding sites were treated, the number of female Anopheles spp. was reduced by 70% (95% CI 64–74%) compared to the pre-intervention period. Conclusion It was shown that malaria vector abundance can be dramatically reduced through larviciding of breeding habitats and that, in many geographical settings, they are a viable addition to current malaria control measures. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 18 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Bacillus thuringiensis israelensis Vector control Anopheles Larval source management Burkina Faso Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Bacillus thuringiensis israelensis Vector control Anopheles Larval source management Burkina Faso Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Peter Dambach Till Baernighausen Issouf Traoré Saidou Ouedraogo Ali Sié Rainer Sauerborn Norbert Becker Valérie R. Louis Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
topic_facet |
Bacillus thuringiensis israelensis Vector control Anopheles Larval source management Burkina Faso Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis and treatment of malaria cases and intermittent preventive treatment in pregnancy (IPTp), vector control is an important tool in the reduction of new cases. Alongside the use of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), targeting the vector larvae with biological larvicides, such as Bacillus thuringiensis israelensis (Bti) is gaining importance as a means of reducing the number of mosquito larvae before they emerge to their adult stage. This study presents data corroborating the entomological impact of such an intervention in a rural African environment. Methods The study extended over 2 years and researched the impact of biological larviciding with Bti on malaria mosquitoes that were caught indoors and outdoors of houses using light traps. The achieved reductions in female Anopheles mosquitoes were calculated for two different larviciding choices using a regression model. Results In villages that received selective treatment of the most productive breeding sites, the number of female Anopheles spp. dropped by 61% (95% CI 54–66%) compared to the pre-intervention period. In villages in which all breeding sites were treated, the number of female Anopheles spp. was reduced by 70% (95% CI 64–74%) compared to the pre-intervention period. Conclusion It was shown that malaria vector abundance can be dramatically reduced through larviciding of breeding habitats and that, in many geographical settings, they are a viable addition to current malaria control measures. |
format |
Article in Journal/Newspaper |
author |
Peter Dambach Till Baernighausen Issouf Traoré Saidou Ouedraogo Ali Sié Rainer Sauerborn Norbert Becker Valérie R. Louis |
author_facet |
Peter Dambach Till Baernighausen Issouf Traoré Saidou Ouedraogo Ali Sié Rainer Sauerborn Norbert Becker Valérie R. Louis |
author_sort |
Peter Dambach |
title |
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
title_short |
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
title_full |
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
title_fullStr |
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
title_full_unstemmed |
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management |
title_sort |
reduction of malaria vector mosquitoes in a large-scale intervention trial in rural burkina faso using bti based larval source management |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12936-019-2951-3 https://doaj.org/article/8d2575125bd84c39b4ec2854b71b3992 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s12936-019-2951-3 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2951-3 1475-2875 https://doaj.org/article/8d2575125bd84c39b4ec2854b71b3992 |
op_doi |
https://doi.org/10.1186/s12936-019-2951-3 |
container_title |
Malaria Journal |
container_volume |
18 |
container_issue |
1 |
_version_ |
1766343140699013120 |