Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases
Objective: To describe the clinical presentation, underlying diseases, antimicrobial susceptibility, treatment and outcome of Klebsiella pneumoniae meningitis patients. Methods: This retrospective study involved all patients with 15 years of age or older who admitted to Hamad General Hospital with c...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2014
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ftdoajarticles:oai:doaj.org/article:8c153d59d50f4d688ba1fdee31f39e50 2023-05-15T15:07:18+02:00 Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases Fahmi Yousef Khan Mohammed Abukhattab Mohammed AbuKamar Deshmukh Anand 2014-08-01T00:00:00Z https://doi.org/10.12980/APJTB.4.201414B100 https://doaj.org/article/8c153d59d50f4d688ba1fdee31f39e50 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S222116911530085X https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B100 https://doaj.org/article/8c153d59d50f4d688ba1fdee31f39e50 Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 8, Pp 669-672 (2014) Nosocomial meningitis Community-acquired meningitis Klebsiella pneumoniae meningitis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.12980/APJTB.4.201414B100 2022-12-31T12:07:48Z Objective: To describe the clinical presentation, underlying diseases, antimicrobial susceptibility, treatment and outcome of Klebsiella pneumoniae meningitis patients. Methods: This retrospective study involved all patients with 15 years of age or older who admitted to Hamad General Hospital with culture proven Klebsiella pneumoniae meningitis from January 1, 2007 to December 31, 2012. Results: A total of ten cases were identified (nine males and one female). Their mean age was (43.3±12.8) years. Eight patients (80%) had nosocomial meningitis with neurosurgery being the most frequent associated condition. Fever and altered consciousness were the most frequent symptom. Cerebrospinal fluid showed elevated protein and glucose levels. Gram stain showed Gram-negative rods in 50% of cases, while positive cerebrospinal fluid culture results were found in all patients. Multidrug resistance was observed in two cases, and all patients had received appropriate empirical and definitive antibiotic treatments. The mean duration of intravenous antimicrobial treatment was (19.3±7.0) d and all patients with external ventricular drains underwent removal of the device, while in-hospital mortality was 50%. Conclusions: The number of cases was too small to come up with therapeutic and prognostic conclusions. Further large-scale prospective study is needed. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 8 669 672 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Nosocomial meningitis Community-acquired meningitis Klebsiella pneumoniae meningitis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Nosocomial meningitis Community-acquired meningitis Klebsiella pneumoniae meningitis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Fahmi Yousef Khan Mohammed Abukhattab Mohammed AbuKamar Deshmukh Anand Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
topic_facet |
Nosocomial meningitis Community-acquired meningitis Klebsiella pneumoniae meningitis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To describe the clinical presentation, underlying diseases, antimicrobial susceptibility, treatment and outcome of Klebsiella pneumoniae meningitis patients. Methods: This retrospective study involved all patients with 15 years of age or older who admitted to Hamad General Hospital with culture proven Klebsiella pneumoniae meningitis from January 1, 2007 to December 31, 2012. Results: A total of ten cases were identified (nine males and one female). Their mean age was (43.3±12.8) years. Eight patients (80%) had nosocomial meningitis with neurosurgery being the most frequent associated condition. Fever and altered consciousness were the most frequent symptom. Cerebrospinal fluid showed elevated protein and glucose levels. Gram stain showed Gram-negative rods in 50% of cases, while positive cerebrospinal fluid culture results were found in all patients. Multidrug resistance was observed in two cases, and all patients had received appropriate empirical and definitive antibiotic treatments. The mean duration of intravenous antimicrobial treatment was (19.3±7.0) d and all patients with external ventricular drains underwent removal of the device, while in-hospital mortality was 50%. Conclusions: The number of cases was too small to come up with therapeutic and prognostic conclusions. Further large-scale prospective study is needed. |
format |
Article in Journal/Newspaper |
author |
Fahmi Yousef Khan Mohammed Abukhattab Mohammed AbuKamar Deshmukh Anand |
author_facet |
Fahmi Yousef Khan Mohammed Abukhattab Mohammed AbuKamar Deshmukh Anand |
author_sort |
Fahmi Yousef Khan |
title |
Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
title_short |
Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
title_full |
Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
title_fullStr |
Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
title_full_unstemmed |
Adult K lebsiella pneumoniae meningitis in Qatar: clinical pattern of ten cases |
title_sort |
adult k lebsiella pneumoniae meningitis in qatar: clinical pattern of ten cases |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.12980/APJTB.4.201414B100 https://doaj.org/article/8c153d59d50f4d688ba1fdee31f39e50 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 8, Pp 669-672 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S222116911530085X https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B100 https://doaj.org/article/8c153d59d50f4d688ba1fdee31f39e50 |
op_doi |
https://doi.org/10.12980/APJTB.4.201414B100 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_issue |
8 |
container_start_page |
669 |
op_container_end_page |
672 |
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1766338838431531008 |