Prostatic cryptococcosis: a case report
Cryptococcosis is a systemic mycosis usually affecting immunodeficient individuals. In contrast, immunologically competent patients are rarely affected. Dissemination of cryptococcosis usually involves the central nervous system, manifesting as meningitis or meningoencephalitis. Prostatic lesions ar...
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ftdoajarticles:oai:doaj.org/article:8bf240d1e8044539884e3b9141febd4e 2023-05-15T15:07:48+02:00 Prostatic cryptococcosis: a case report M. R. Chang A. M. M. Paniago M. M. Silva M. S. Lazéra B. Wanke 2008-01-01T00:00:00Z https://doi.org/10.1590/S1678-91992008000200015 https://doaj.org/article/8bf240d1e8044539884e3b9141febd4e EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200015 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000200015 1678-9199 https://doaj.org/article/8bf240d1e8044539884e3b9141febd4e Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 2, Pp 378-385 (2008) Cryptococcosis Cryptococcus immunocompetent patient cryptococcal prostatitis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2008 ftdoajarticles https://doi.org/10.1590/S1678-91992008000200015 2022-12-31T00:13:24Z Cryptococcosis is a systemic mycosis usually affecting immunodeficient individuals. In contrast, immunologically competent patients are rarely affected. Dissemination of cryptococcosis usually involves the central nervous system, manifesting as meningitis or meningoencephalitis. Prostatic lesions are not commonly found. A case of prostate cryptococcal infection is presented and cases of prostatic cryptococcosis in normal and immunocompromised hosts are reviewed. A fifty-year-old HIV-negative man with urinary retention and renal insufficiency underwent prostatectomy due to massive enlargement of the organ. Prostate histopathologic examination revealed encapsulated yeast-like structures. After 30 days, the patient's clinical manifestations worsened, with headache, neck stiffness, bradypsychia, vomiting and fever. Direct microscopy of the patient's urine with China ink preparations showed capsulated yeasts, and positive culture yielded Cryptococcus neoformans. This fungus was later isolated from cerebrospinal fluid and blood cultures, demonstrating thus its dissemination. The patient was discharged after 27 days in hospital and, despite a regimen of amphotericin B, he died four months later. This case points to cryptococcosis as a possible cause of prostatic disease and reinforces the importance of communication between the medical team and pathology and microbiology laboratories aiming at a more accurate diagnosis and successful treatment. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 14 2 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Cryptococcosis Cryptococcus immunocompetent patient cryptococcal prostatitis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Cryptococcosis Cryptococcus immunocompetent patient cryptococcal prostatitis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 M. R. Chang A. M. M. Paniago M. M. Silva M. S. Lazéra B. Wanke Prostatic cryptococcosis: a case report |
topic_facet |
Cryptococcosis Cryptococcus immunocompetent patient cryptococcal prostatitis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Cryptococcosis is a systemic mycosis usually affecting immunodeficient individuals. In contrast, immunologically competent patients are rarely affected. Dissemination of cryptococcosis usually involves the central nervous system, manifesting as meningitis or meningoencephalitis. Prostatic lesions are not commonly found. A case of prostate cryptococcal infection is presented and cases of prostatic cryptococcosis in normal and immunocompromised hosts are reviewed. A fifty-year-old HIV-negative man with urinary retention and renal insufficiency underwent prostatectomy due to massive enlargement of the organ. Prostate histopathologic examination revealed encapsulated yeast-like structures. After 30 days, the patient's clinical manifestations worsened, with headache, neck stiffness, bradypsychia, vomiting and fever. Direct microscopy of the patient's urine with China ink preparations showed capsulated yeasts, and positive culture yielded Cryptococcus neoformans. This fungus was later isolated from cerebrospinal fluid and blood cultures, demonstrating thus its dissemination. The patient was discharged after 27 days in hospital and, despite a regimen of amphotericin B, he died four months later. This case points to cryptococcosis as a possible cause of prostatic disease and reinforces the importance of communication between the medical team and pathology and microbiology laboratories aiming at a more accurate diagnosis and successful treatment. |
format |
Article in Journal/Newspaper |
author |
M. R. Chang A. M. M. Paniago M. M. Silva M. S. Lazéra B. Wanke |
author_facet |
M. R. Chang A. M. M. Paniago M. M. Silva M. S. Lazéra B. Wanke |
author_sort |
M. R. Chang |
title |
Prostatic cryptococcosis: a case report |
title_short |
Prostatic cryptococcosis: a case report |
title_full |
Prostatic cryptococcosis: a case report |
title_fullStr |
Prostatic cryptococcosis: a case report |
title_full_unstemmed |
Prostatic cryptococcosis: a case report |
title_sort |
prostatic cryptococcosis: a case report |
publisher |
SciELO |
publishDate |
2008 |
url |
https://doi.org/10.1590/S1678-91992008000200015 https://doaj.org/article/8bf240d1e8044539884e3b9141febd4e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 2, Pp 378-385 (2008) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200015 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000200015 1678-9199 https://doaj.org/article/8bf240d1e8044539884e3b9141febd4e |
op_doi |
https://doi.org/10.1590/S1678-91992008000200015 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
14 |
container_issue |
2 |
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1766339227243511808 |