Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil
Objective: To determine hydrophilicâlipophilic balance (HLB) value, stability of formulate emulsion and properties of sacha inchi oil. Methods: The physiochemical characteristics of sacha inchi oil were first investigated. Free radical scavenging property was studied by DPPH assay. HLB value of sach...
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Wolters Kluwer Medknow Publications
2017
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Online Access: | https://doi.org/10.1016/j.apjtb.2017.10.011 https://doaj.org/article/8bba4d4a10564de2ae7e6065f85f00fc |
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ftdoajarticles:oai:doaj.org/article:8bba4d4a10564de2ae7e6065f85f00fc 2023-05-15T15:12:09+02:00 Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil Kiattiphumi Saengsorn Ampa Jimtaisong 2017-12-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.10.011 https://doaj.org/article/8bba4d4a10564de2ae7e6065f85f00fc EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117310134 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.10.011 https://doaj.org/article/8bba4d4a10564de2ae7e6065f85f00fc Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 12, Pp 1092-1096 (2017) Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.10.011 2022-12-30T21:37:14Z Objective: To determine hydrophilicâlipophilic balance (HLB) value, stability of formulate emulsion and properties of sacha inchi oil. Methods: The physiochemical characteristics of sacha inchi oil were first investigated. Free radical scavenging property was studied by DPPH assay. HLB value of sacha inchi oil was experimentally determined by preparing the emulsion using emulsifiers at different HLB value. Sacha inchi oil emulsion was prepared using the obtained HLB and its stability was conducted by centrifugation, temperature cycling, and accelerated stability test. The efficiency of the prepared emulsion was clinically investigated by 15 volunteers. The primary skin irritation was performed using closed patch test. Subjective sensory assessment was evaluated by using 5-point hedonic scale method. Results: Peroxide value of sacha inchi oil was 18.40Â meq O2/kg oil and acid value was 1.86 KOH/g oil. The major fatty acids are omega-3 (44%), omega-6 (35%) and omega-9 (9%). The vitamin E content was 226Â mg/100Â g oil. Moreover, sacha inchi oil (167Â ppm) and its emulsion showed 85% and 89% DPPH inhibition, respectively. The experimental HLB value of sacha inchi oil was 8.5. The sacha inchi oil emulsion exhibited good stability after stability test. The emulsion was classified as non-irritant after tested by primary skin irritation method. The skin hydration value significantly increased from 38.59 to 45.21 (PÂ <Â 0.05) after applying sacha inchi oil emulsion for 1 month and the overall product satisfaction of volunteers after use was with score of 4.2. Conclusions: This work provides information on HLB value and emulsion properties of sacha inchi oil which is useful for cosmetic and pharmaceutical application. Keywords: Sacha inchi oil, Hydrophilicâlipophilic balance value, Emulsion stability, Efficacy test, Sensory test Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 12 1092 1096 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Kiattiphumi Saengsorn Ampa Jimtaisong Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To determine hydrophilicâlipophilic balance (HLB) value, stability of formulate emulsion and properties of sacha inchi oil. Methods: The physiochemical characteristics of sacha inchi oil were first investigated. Free radical scavenging property was studied by DPPH assay. HLB value of sacha inchi oil was experimentally determined by preparing the emulsion using emulsifiers at different HLB value. Sacha inchi oil emulsion was prepared using the obtained HLB and its stability was conducted by centrifugation, temperature cycling, and accelerated stability test. The efficiency of the prepared emulsion was clinically investigated by 15 volunteers. The primary skin irritation was performed using closed patch test. Subjective sensory assessment was evaluated by using 5-point hedonic scale method. Results: Peroxide value of sacha inchi oil was 18.40Â meq O2/kg oil and acid value was 1.86 KOH/g oil. The major fatty acids are omega-3 (44%), omega-6 (35%) and omega-9 (9%). The vitamin E content was 226Â mg/100Â g oil. Moreover, sacha inchi oil (167Â ppm) and its emulsion showed 85% and 89% DPPH inhibition, respectively. The experimental HLB value of sacha inchi oil was 8.5. The sacha inchi oil emulsion exhibited good stability after stability test. The emulsion was classified as non-irritant after tested by primary skin irritation method. The skin hydration value significantly increased from 38.59 to 45.21 (PÂ <Â 0.05) after applying sacha inchi oil emulsion for 1 month and the overall product satisfaction of volunteers after use was with score of 4.2. Conclusions: This work provides information on HLB value and emulsion properties of sacha inchi oil which is useful for cosmetic and pharmaceutical application. Keywords: Sacha inchi oil, Hydrophilicâlipophilic balance value, Emulsion stability, Efficacy test, Sensory test |
format |
Article in Journal/Newspaper |
author |
Kiattiphumi Saengsorn Ampa Jimtaisong |
author_facet |
Kiattiphumi Saengsorn Ampa Jimtaisong |
author_sort |
Kiattiphumi Saengsorn |
title |
Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
title_short |
Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
title_full |
Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
title_fullStr |
Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
title_full_unstemmed |
Determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
title_sort |
determination of hydrophilicâlipophilic balance value and emulsion properties of sacha inchi oil |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.10.011 https://doaj.org/article/8bba4d4a10564de2ae7e6065f85f00fc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 12, Pp 1092-1096 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117310134 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.10.011 https://doaj.org/article/8bba4d4a10564de2ae7e6065f85f00fc |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.10.011 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
12 |
container_start_page |
1092 |
op_container_end_page |
1096 |
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1766342866704007168 |