Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal
Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted. Materials and methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in th...
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ftdoajarticles:oai:doaj.org/article:8a98fb22507e4fe9a1763d4076fc39c3 2024-09-09T19:26:29+00:00 Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal Ihssane Ouaddane Ndiaw Goumballa Xuan Duong Tran Coumba Diouf Seydina M. Diene Jean-Marc Rolain Cheikh Sokhna Philippe Gautret 2024-05-01T00:00:00Z https://doi.org/10.1016/j.tmaid.2024.102709 https://doaj.org/article/8a98fb22507e4fe9a1763d4076fc39c3 EN eng Elsevier http://www.sciencedirect.com/science/article/pii/S1477893924000231 https://doaj.org/toc/1873-0442 1873-0442 doi:10.1016/j.tmaid.2024.102709 https://doaj.org/article/8a98fb22507e4fe9a1763d4076fc39c3 Travel Medicine and Infectious Disease, Vol 59, Iss , Pp 102709- (2024) Grand magal of touba Pilgrims Gastrointestinal infections Bacterial resistance qPCR Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2024 ftdoajarticles https://doi.org/10.1016/j.tmaid.2024.102709 2024-08-05T17:49:25Z Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted. Materials and methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in the gathering. Rectal samples from between 2018 and 2020 were also cultured on specific media, and antibiotic susceptibility testing was performed. Results: Forty-one of the 296 (13.8%) pilgrims had at least one gastrointestinal symptom and 91/290 (31.4%) acquired pathogenic bacteria, mostly Escherichia coli. A total of 54.7% of pilgrims reported washing their hands more frequently than usual and 89.2% used soap. One hundred and five (36.2%) acquired at least one resistance gene, notably CTX-M A (21.0%), SHV (16.5%) and TEM (8.2%). The strains isolated by culture were mostly E. coli. These bacteria were found to be sensitive to carbapenems and resistant to amoxicillin and amoxicillin-clavulanic acid. The acquisition of enteroaggregative E. coli was independently associated with CTX-M A and TEM acquisition. Conclusion: Pilgrims presented a risk for acquisition of CTX-M A after the GMT. Surveillance of the prevalence of resistant bacteria and the occurrence of associated clinical infections among pilgrims are necessary in the future. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Travel Medicine and Infectious Disease 59 102709 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Grand magal of touba Pilgrims Gastrointestinal infections Bacterial resistance qPCR Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Grand magal of touba Pilgrims Gastrointestinal infections Bacterial resistance qPCR Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Ihssane Ouaddane Ndiaw Goumballa Xuan Duong Tran Coumba Diouf Seydina M. Diene Jean-Marc Rolain Cheikh Sokhna Philippe Gautret Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
topic_facet |
Grand magal of touba Pilgrims Gastrointestinal infections Bacterial resistance qPCR Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted. Materials and methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in the gathering. Rectal samples from between 2018 and 2020 were also cultured on specific media, and antibiotic susceptibility testing was performed. Results: Forty-one of the 296 (13.8%) pilgrims had at least one gastrointestinal symptom and 91/290 (31.4%) acquired pathogenic bacteria, mostly Escherichia coli. A total of 54.7% of pilgrims reported washing their hands more frequently than usual and 89.2% used soap. One hundred and five (36.2%) acquired at least one resistance gene, notably CTX-M A (21.0%), SHV (16.5%) and TEM (8.2%). The strains isolated by culture were mostly E. coli. These bacteria were found to be sensitive to carbapenems and resistant to amoxicillin and amoxicillin-clavulanic acid. The acquisition of enteroaggregative E. coli was independently associated with CTX-M A and TEM acquisition. Conclusion: Pilgrims presented a risk for acquisition of CTX-M A after the GMT. Surveillance of the prevalence of resistant bacteria and the occurrence of associated clinical infections among pilgrims are necessary in the future. |
format |
Article in Journal/Newspaper |
author |
Ihssane Ouaddane Ndiaw Goumballa Xuan Duong Tran Coumba Diouf Seydina M. Diene Jean-Marc Rolain Cheikh Sokhna Philippe Gautret |
author_facet |
Ihssane Ouaddane Ndiaw Goumballa Xuan Duong Tran Coumba Diouf Seydina M. Diene Jean-Marc Rolain Cheikh Sokhna Philippe Gautret |
author_sort |
Ihssane Ouaddane |
title |
Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
title_short |
Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
title_full |
Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
title_fullStr |
Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
title_full_unstemmed |
Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal |
title_sort |
epidemiology of bacterial resistance at the grand magal of touba in senegal |
publisher |
Elsevier |
publishDate |
2024 |
url |
https://doi.org/10.1016/j.tmaid.2024.102709 https://doaj.org/article/8a98fb22507e4fe9a1763d4076fc39c3 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Travel Medicine and Infectious Disease, Vol 59, Iss , Pp 102709- (2024) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S1477893924000231 https://doaj.org/toc/1873-0442 1873-0442 doi:10.1016/j.tmaid.2024.102709 https://doaj.org/article/8a98fb22507e4fe9a1763d4076fc39c3 |
op_doi |
https://doi.org/10.1016/j.tmaid.2024.102709 |
container_title |
Travel Medicine and Infectious Disease |
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59 |
container_start_page |
102709 |
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1809896088970199040 |