Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network
Introduction: Newfoundland and Labrador (NL) has the highest prevalence of cardiovascular disease (CVD) in Canada. Dyslipidemia is a risk factor for cardiovascular disease. This study compares the prevalence of dyslipidemia in the NL population with the rest of Canada.Methods: A cross-sectional s...
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2015
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ftdoajarticles:oai:doaj.org/article:89f30f3ee37d408db2d8f58874998cb5 2023-05-15T17:21:23+02:00 Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network Shabnam eAsghari Erfan eAref-Eshghi Oliver eHurley Marshall eGodwin Pauline eDuke Tyler eWilliamson Masoud eMahdavian 2015-02-01T00:00:00Z https://doi.org/10.3389/fcvm.2015.00001 https://doaj.org/article/89f30f3ee37d408db2d8f58874998cb5 EN eng Frontiers Media S.A. http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00001/full https://doaj.org/toc/2297-055X 2297-055X doi:10.3389/fcvm.2015.00001 https://doaj.org/article/89f30f3ee37d408db2d8f58874998cb5 Frontiers in Cardiovascular Medicine, Vol 2 (2015) Canada Prevalence Dyslipidemia lipid profile Newfoundland Canadian Primary Care Sentinel Surveillance Network Diseases of the circulatory (Cardiovascular) system RC666-701 article 2015 ftdoajarticles https://doi.org/10.3389/fcvm.2015.00001 2022-12-31T03:09:26Z Introduction: Newfoundland and Labrador (NL) has the highest prevalence of cardiovascular disease (CVD) in Canada. Dyslipidemia is a risk factor for cardiovascular disease. This study compares the prevalence of dyslipidemia in the NL population with the rest of Canada.Methods: A cross-sectional study, using data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), was undertaken. The study population included adults, excluding pregnant women, aged 20 years and older. Canadian guidelines were used for classifying dyslipidemia. Univariate and multivariate analyses were conducted to compare the lipid levels and prevalence of dyslipidemia between NL and the rest of Canada.Results: 128,825 individuals (NL: 7,772; rest of Canada: 121,053) were identified with a mean age of 59 years (55% Females). Mean levels of total Cholesterol (4.96 vs. 4.93, P=0.03), LDL (3.00 vs. 2.90 mmol/L, P<0.0001), triglyceride (1.47 vs. 1.41 mmol/L, P<0.0001), and HDL (1.29 vs. 1.39 mmol/L, P<0.0001) were significantly different in NL compared to the rest of Canada. Dyslipidemias of LDL (29% vs. 25% P<0.0001), HDL (38% vs. 27%, P<0.0001), and triglyceride (29% vs. 26%, P<0.0001) were significantly more common in NL. After adjustment for confounding variables, NL inhabitants were more likely to have dyslipidemia of total cholesterol (OR: 1.16, 95% CI: 1.10-1.23, P<0.0001), HDL (OR: 1.52, 95% CI: 1.44-1.60, P<0.0001), LDL (OR: 1.38, 95% CI: 1.30-1.46, P<0.0001), and ratio (OR: 1.53, 95% CI: 1.42-1.60, P<0.0001).Conclusion: The NL population has a significantly higher rate of dyslipidemia compared to the rest of Canada, and the mean levels of all lipid components are worse in NL. Distinct cultural and genetic features of the NL population may explain this, accounting for a higher rate of CVD in NL. Article in Journal/Newspaper Newfoundland Directory of Open Access Journals: DOAJ Articles Canada Newfoundland Frontiers in Cardiovascular Medicine 2 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Canada Prevalence Dyslipidemia lipid profile Newfoundland Canadian Primary Care Sentinel Surveillance Network Diseases of the circulatory (Cardiovascular) system RC666-701 |
spellingShingle |
Canada Prevalence Dyslipidemia lipid profile Newfoundland Canadian Primary Care Sentinel Surveillance Network Diseases of the circulatory (Cardiovascular) system RC666-701 Shabnam eAsghari Erfan eAref-Eshghi Oliver eHurley Marshall eGodwin Pauline eDuke Tyler eWilliamson Masoud eMahdavian Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
topic_facet |
Canada Prevalence Dyslipidemia lipid profile Newfoundland Canadian Primary Care Sentinel Surveillance Network Diseases of the circulatory (Cardiovascular) system RC666-701 |
description |
Introduction: Newfoundland and Labrador (NL) has the highest prevalence of cardiovascular disease (CVD) in Canada. Dyslipidemia is a risk factor for cardiovascular disease. This study compares the prevalence of dyslipidemia in the NL population with the rest of Canada.Methods: A cross-sectional study, using data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), was undertaken. The study population included adults, excluding pregnant women, aged 20 years and older. Canadian guidelines were used for classifying dyslipidemia. Univariate and multivariate analyses were conducted to compare the lipid levels and prevalence of dyslipidemia between NL and the rest of Canada.Results: 128,825 individuals (NL: 7,772; rest of Canada: 121,053) were identified with a mean age of 59 years (55% Females). Mean levels of total Cholesterol (4.96 vs. 4.93, P=0.03), LDL (3.00 vs. 2.90 mmol/L, P<0.0001), triglyceride (1.47 vs. 1.41 mmol/L, P<0.0001), and HDL (1.29 vs. 1.39 mmol/L, P<0.0001) were significantly different in NL compared to the rest of Canada. Dyslipidemias of LDL (29% vs. 25% P<0.0001), HDL (38% vs. 27%, P<0.0001), and triglyceride (29% vs. 26%, P<0.0001) were significantly more common in NL. After adjustment for confounding variables, NL inhabitants were more likely to have dyslipidemia of total cholesterol (OR: 1.16, 95% CI: 1.10-1.23, P<0.0001), HDL (OR: 1.52, 95% CI: 1.44-1.60, P<0.0001), LDL (OR: 1.38, 95% CI: 1.30-1.46, P<0.0001), and ratio (OR: 1.53, 95% CI: 1.42-1.60, P<0.0001).Conclusion: The NL population has a significantly higher rate of dyslipidemia compared to the rest of Canada, and the mean levels of all lipid components are worse in NL. Distinct cultural and genetic features of the NL population may explain this, accounting for a higher rate of CVD in NL. |
format |
Article in Journal/Newspaper |
author |
Shabnam eAsghari Erfan eAref-Eshghi Oliver eHurley Marshall eGodwin Pauline eDuke Tyler eWilliamson Masoud eMahdavian |
author_facet |
Shabnam eAsghari Erfan eAref-Eshghi Oliver eHurley Marshall eGodwin Pauline eDuke Tyler eWilliamson Masoud eMahdavian |
author_sort |
Shabnam eAsghari |
title |
Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
title_short |
Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
title_full |
Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
title_fullStr |
Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
title_full_unstemmed |
Does the prevalence of dyslipidemias differ between Newfoundland and the rest of Canada? Findings from the Electronic Medical Records of the Canadian Primary Care Sentinel Surveillance Network |
title_sort |
does the prevalence of dyslipidemias differ between newfoundland and the rest of canada? findings from the electronic medical records of the canadian primary care sentinel surveillance network |
publisher |
Frontiers Media S.A. |
publishDate |
2015 |
url |
https://doi.org/10.3389/fcvm.2015.00001 https://doaj.org/article/89f30f3ee37d408db2d8f58874998cb5 |
geographic |
Canada Newfoundland |
geographic_facet |
Canada Newfoundland |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Frontiers in Cardiovascular Medicine, Vol 2 (2015) |
op_relation |
http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00001/full https://doaj.org/toc/2297-055X 2297-055X doi:10.3389/fcvm.2015.00001 https://doaj.org/article/89f30f3ee37d408db2d8f58874998cb5 |
op_doi |
https://doi.org/10.3389/fcvm.2015.00001 |
container_title |
Frontiers in Cardiovascular Medicine |
container_volume |
2 |
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1766105613994033152 |