Optimizing one-dose and two-dose cholera vaccine allocation in outbreak settings: A modeling study.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Tiffany Leung, Julia Eaton, Laura Matrajt
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2022
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Rata
• Online Access: https://doi.org/10.1371/journal.pntd.0010358; https://doaj.org/article/89a45d4783e540bcae193c2baa34f5c7

Background A global stockpile of oral cholera vaccine (OCV) was established in 2013 for use in outbreak response and are licensed as two-dose regimens. Vaccine availability, however, remains limited. Previous studies have found that a single dose of OCV may provide substantial protection against cho...