Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK
Tetrodotoxins (TTXs) are traditionally associated with the occurrence of tropical Pufferfish Poisoning. In recent years, however, TTXs have been identified in European bivalve mollusc shellfish, resulting in the need to assess prevalence and risk to shellfish consumers. Following the previous identi...
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ftdoajarticles:oai:doaj.org/article:88f0606163c649218e07e5087eced2ac 2023-05-15T15:58:46+02:00 Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK Andrew D. Turner Monika Dhanji-Rapkova Lewis Coates Lesley Bickerstaff Steve Milligan Alison O’Neill Dermot Faulkner Hugh McEneny Craig Baker-Austin David N. Lees Myriam Algoet 2017-08-01T00:00:00Z https://doi.org/10.3390/md15090277 https://doaj.org/article/88f0606163c649218e07e5087eced2ac EN eng MDPI AG https://www.mdpi.com/1660-3397/15/9/277 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md15090277 https://doaj.org/article/88f0606163c649218e07e5087eced2ac Marine Drugs, Vol 15, Iss 9, p 277 (2017) Tetrodotoxins bivalve molluscs HILIC-MS/MS UK shellfish Tetrodotoxin Shellfish Poisoning (TSP) Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.3390/md15090277 2022-12-30T20:04:48Z Tetrodotoxins (TTXs) are traditionally associated with the occurrence of tropical Pufferfish Poisoning. In recent years, however, TTXs have been identified in European bivalve mollusc shellfish, resulting in the need to assess prevalence and risk to shellfish consumers. Following the previous identification of TTXs in shellfish from southern England, this study was designed to assess the wider prevalence of TTXs in shellfish from around the coast of the UK. Samples were collected between 2014 and 2016 and subjected to analysis using HILIC-MS/MS. Results showed the continued presence of toxins in shellfish harvested along the coast of southern England, with the maximum concentration of total TTXs reaching 253 µg/kg. TTX accumulation was detected in Pacific oysters (Crassostrea gigas), native oysters (Ostrea edulis) common mussels (Mytilus edulis) and hard clams (Mercenaria mercenaria), but not found in cockles (Cerastoderma edule), razors (Ensis species) or scallops (Pecten maximus). Whilst the highest concentrations were quantified in samples harvested during the warmer summer months, TTXs were still evident during the winter. An assessment of the potential causative factors did not reveal any links with the phytoplankton species Prorocentrum cordatum, instead highlighting a greater level of risk in areas of shallow, estuarine waters with temperatures above 15 °C. Article in Journal/Newspaper Crassostrea gigas Directory of Open Access Journals: DOAJ Articles Pacific Marine Drugs 15 9 277 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Tetrodotoxins bivalve molluscs HILIC-MS/MS UK shellfish Tetrodotoxin Shellfish Poisoning (TSP) Biology (General) QH301-705.5 |
spellingShingle |
Tetrodotoxins bivalve molluscs HILIC-MS/MS UK shellfish Tetrodotoxin Shellfish Poisoning (TSP) Biology (General) QH301-705.5 Andrew D. Turner Monika Dhanji-Rapkova Lewis Coates Lesley Bickerstaff Steve Milligan Alison O’Neill Dermot Faulkner Hugh McEneny Craig Baker-Austin David N. Lees Myriam Algoet Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
topic_facet |
Tetrodotoxins bivalve molluscs HILIC-MS/MS UK shellfish Tetrodotoxin Shellfish Poisoning (TSP) Biology (General) QH301-705.5 |
description |
Tetrodotoxins (TTXs) are traditionally associated with the occurrence of tropical Pufferfish Poisoning. In recent years, however, TTXs have been identified in European bivalve mollusc shellfish, resulting in the need to assess prevalence and risk to shellfish consumers. Following the previous identification of TTXs in shellfish from southern England, this study was designed to assess the wider prevalence of TTXs in shellfish from around the coast of the UK. Samples were collected between 2014 and 2016 and subjected to analysis using HILIC-MS/MS. Results showed the continued presence of toxins in shellfish harvested along the coast of southern England, with the maximum concentration of total TTXs reaching 253 µg/kg. TTX accumulation was detected in Pacific oysters (Crassostrea gigas), native oysters (Ostrea edulis) common mussels (Mytilus edulis) and hard clams (Mercenaria mercenaria), but not found in cockles (Cerastoderma edule), razors (Ensis species) or scallops (Pecten maximus). Whilst the highest concentrations were quantified in samples harvested during the warmer summer months, TTXs were still evident during the winter. An assessment of the potential causative factors did not reveal any links with the phytoplankton species Prorocentrum cordatum, instead highlighting a greater level of risk in areas of shallow, estuarine waters with temperatures above 15 °C. |
format |
Article in Journal/Newspaper |
author |
Andrew D. Turner Monika Dhanji-Rapkova Lewis Coates Lesley Bickerstaff Steve Milligan Alison O’Neill Dermot Faulkner Hugh McEneny Craig Baker-Austin David N. Lees Myriam Algoet |
author_facet |
Andrew D. Turner Monika Dhanji-Rapkova Lewis Coates Lesley Bickerstaff Steve Milligan Alison O’Neill Dermot Faulkner Hugh McEneny Craig Baker-Austin David N. Lees Myriam Algoet |
author_sort |
Andrew D. Turner |
title |
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
title_short |
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
title_full |
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
title_fullStr |
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
title_full_unstemmed |
Detection of Tetrodotoxin Shellfish Poisoning (TSP) Toxins and Causative Factors in Bivalve Molluscs from the UK |
title_sort |
detection of tetrodotoxin shellfish poisoning (tsp) toxins and causative factors in bivalve molluscs from the uk |
publisher |
MDPI AG |
publishDate |
2017 |
url |
https://doi.org/10.3390/md15090277 https://doaj.org/article/88f0606163c649218e07e5087eced2ac |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_source |
Marine Drugs, Vol 15, Iss 9, p 277 (2017) |
op_relation |
https://www.mdpi.com/1660-3397/15/9/277 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md15090277 https://doaj.org/article/88f0606163c649218e07e5087eced2ac |
op_doi |
https://doi.org/10.3390/md15090277 |
container_title |
Marine Drugs |
container_volume |
15 |
container_issue |
9 |
container_start_page |
277 |
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1766394546659262464 |