The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda.
Background Despite decades of community-based mass drug administration (MDA) for neglected tropical diseases, it remains an open question as to what constitutes the best combination of community medicine distributors (CMDs) for achieving high (>65%/75%) treatment rates within a village. Methods R...
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ftdoajarticles:oai:doaj.org/article:8890bbbce7bc413a9ba75e7bb3942a93 2023-05-15T15:16:43+02:00 The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. Goylette F Chami Narcis B Kabatereine Edridah M Tukahebwa 2019-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007685 https://doaj.org/article/8890bbbce7bc413a9ba75e7bb3942a93 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0007685 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007685 https://doaj.org/article/8890bbbce7bc413a9ba75e7bb3942a93 PLoS Neglected Tropical Diseases, Vol 13, Iss 9, p e0007685 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007685 2022-12-31T05:04:46Z Background Despite decades of community-based mass drug administration (MDA) for neglected tropical diseases, it remains an open question as to what constitutes the best combination of community medicine distributors (CMDs) for achieving high (>65%/75%) treatment rates within a village. Methods Routine community-based MDA was evaluated in Mayuge District, Uganda. For one month, we tracked 6,148 individuals aged 1+ years in 1,118 households from 28 villages. Praziquantel, albendazole, and ivermectin were distributed to treat Schistosoma mansoni, lymphatic filariasis, and soil-transmitted helminths. The similarity/diversity between CMDs was observed and used to predict the division of labour and overall village treatment rates. The division of labour was calculated by dividing the lowest treatment rate by the highest treatment rate achieved by two CMDs within a village. CMD similarity was measured for 16 characteristics including friendship network overlap, demographic and socioeconomic factors, methods of CMD selection, and years as CMD. Relevant variables for MDA outcomes were selected through least absolute shrinkage and selection operators with leave-one-out cross validation. Final models were run with ordinary least squares regression and robust standard errors. Results The percentage of individuals treated with at least one drug varied across villages from 2.79-89.74%. The only significant predictor (p-value<0.05) of village treatment rates was the division of labour. The estimated difference between a perfectly equal (a 50-50 split of individuals treated) and unequal (one CMD treating no one) division of labour was 39.69%. A direct tie (close friendship) between CMDs was associated with a nearly twofold more equitable distribution of labour when compared to CMDs without a direct tie. Conclusions An equitable distribution of labour between CMDs may be essential for achieving treatment targets of 65%/75% within community-based MDA. To improve the effectiveness of CMDs, national programmes should explore ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 13 9 e0007685 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Goylette F Chami Narcis B Kabatereine Edridah M Tukahebwa The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Despite decades of community-based mass drug administration (MDA) for neglected tropical diseases, it remains an open question as to what constitutes the best combination of community medicine distributors (CMDs) for achieving high (>65%/75%) treatment rates within a village. Methods Routine community-based MDA was evaluated in Mayuge District, Uganda. For one month, we tracked 6,148 individuals aged 1+ years in 1,118 households from 28 villages. Praziquantel, albendazole, and ivermectin were distributed to treat Schistosoma mansoni, lymphatic filariasis, and soil-transmitted helminths. The similarity/diversity between CMDs was observed and used to predict the division of labour and overall village treatment rates. The division of labour was calculated by dividing the lowest treatment rate by the highest treatment rate achieved by two CMDs within a village. CMD similarity was measured for 16 characteristics including friendship network overlap, demographic and socioeconomic factors, methods of CMD selection, and years as CMD. Relevant variables for MDA outcomes were selected through least absolute shrinkage and selection operators with leave-one-out cross validation. Final models were run with ordinary least squares regression and robust standard errors. Results The percentage of individuals treated with at least one drug varied across villages from 2.79-89.74%. The only significant predictor (p-value<0.05) of village treatment rates was the division of labour. The estimated difference between a perfectly equal (a 50-50 split of individuals treated) and unequal (one CMD treating no one) division of labour was 39.69%. A direct tie (close friendship) between CMDs was associated with a nearly twofold more equitable distribution of labour when compared to CMDs without a direct tie. Conclusions An equitable distribution of labour between CMDs may be essential for achieving treatment targets of 65%/75% within community-based MDA. To improve the effectiveness of CMDs, national programmes should explore ... |
format |
Article in Journal/Newspaper |
author |
Goylette F Chami Narcis B Kabatereine Edridah M Tukahebwa |
author_facet |
Goylette F Chami Narcis B Kabatereine Edridah M Tukahebwa |
author_sort |
Goylette F Chami |
title |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
title_short |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
title_full |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
title_fullStr |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
title_full_unstemmed |
The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda. |
title_sort |
division of labour between community medicine distributors influences the reach of mass drug administration: a cross-sectional study in rural uganda. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0007685 https://doaj.org/article/8890bbbce7bc413a9ba75e7bb3942a93 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 9, p e0007685 (2019) |
op_relation |
https://doi.org/10.1371/journal.pntd.0007685 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007685 https://doaj.org/article/8890bbbce7bc413a9ba75e7bb3942a93 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007685 |
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PLOS Neglected Tropical Diseases |
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13 |
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9 |
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e0007685 |
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