Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study

Abstract Background Globally, in 2016, about 38% and 3% of all neonatal death were recorded in sub-Saharan Africa and Ethiopia, respectively. In the same year, 47 neonates out of 1000 live births were not surviving in the first 28 days of age in the Amhara region, Ethiopia. Despite the highest burde...

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Published in:Tropical Medicine and Health
Main Authors: Abebaw Yeshambel Alemu, Getaneh Mulualem Belay, Mengistu Berhanu, Biniam Minuye
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2020
Subjects:
Online Access:https://doi.org/10.1186/s41182-020-00232-9
https://doaj.org/article/8883e0d08b03450b84bb0dac7e731e56
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spelling ftdoajarticles:oai:doaj.org/article:8883e0d08b03450b84bb0dac7e731e56 2023-05-15T15:15:09+02:00 Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study Abebaw Yeshambel Alemu Getaneh Mulualem Belay Mengistu Berhanu Biniam Minuye 2020-06-01T00:00:00Z https://doi.org/10.1186/s41182-020-00232-9 https://doaj.org/article/8883e0d08b03450b84bb0dac7e731e56 EN eng BMC http://link.springer.com/article/10.1186/s41182-020-00232-9 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-020-00232-9 1349-4147 https://doaj.org/article/8883e0d08b03450b84bb0dac7e731e56 Tropical Medicine and Health, Vol 48, Iss 1, Pp 1-10 (2020) Neonatal mortality Neonatal factors Neonatal intensive care unit Northeast Ethiopia Arctic medicine. Tropical medicine RC955-962 article 2020 ftdoajarticles https://doi.org/10.1186/s41182-020-00232-9 2022-12-31T12:48:13Z Abstract Background Globally, in 2016, about 38% and 3% of all neonatal death were recorded in sub-Saharan Africa and Ethiopia, respectively. In the same year, 47 neonates out of 1000 live births were not surviving in the first 28 days of age in the Amhara region, Ethiopia. Despite the highest burden of neonatal death in the region, specific or the proximate determinants of neonatal death in the neonatal intensive care unit were not well identified. Objective This study aimed to identify the determinants of neonatal mortality at neonatal intensive care unit in Dessie Referral Hospital, Northeast Ethiopia. Methods An institution-based unmatched case-control study was conducted on neonates admitted to the neonatal intensive care unit of Dessie Referral Hospital, from January 1, 2016, to December 30, 2017. A total of 390 charts (130 cases and 260 controls) were selected by simple random sampling technique. The data were abstracted from the facility-based data abstraction form. A binary logistic regression analysis was fitted to identify the determinants of neonatal mortality. Results Pregnancy-induced hypertension (AOR = 4.57; 95% CI 1.45–14.43), prolonged rupture of membrane (AOR = 2.04; 95% CI 1.13–3.68), very low birth weight (AOR = 7.00; 95% CI 2.10–23.35), and low birth weight (AOR = 2.12; 95% CI 1.10–4.20) were identified factors. Moreover, respiratory distress syndrome (AOR = 3.61; 95% CI 1.10–12.04), perinatal asphyxia (AOR = 2.27; 95% CI 1.18–4.39), meconium aspiration syndrome (AOR = 2.35; 95% CI 1.12–4.97), and infection (AOR = 2.26; 95% CI 1.34–3.82) were also significantly associated with neonatal death. Conclusions Pregnancy-induced hypertension, prolonged rupture of membrane, low birth weight, respiratory distress syndrome, perinatal asphyxia, meconium aspiration syndrome, and infections were the major determinants of neonatal mortality. Therefore, special attention will be given to small and sick babies. Moreover, early anticipation of complications and management of mothers who had ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 48 1
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Neonatal mortality
Neonatal factors
Neonatal intensive care unit
Northeast Ethiopia
Arctic medicine. Tropical medicine
RC955-962
spellingShingle Neonatal mortality
Neonatal factors
Neonatal intensive care unit
Northeast Ethiopia
Arctic medicine. Tropical medicine
RC955-962
Abebaw Yeshambel Alemu
Getaneh Mulualem Belay
Mengistu Berhanu
Biniam Minuye
Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
topic_facet Neonatal mortality
Neonatal factors
Neonatal intensive care unit
Northeast Ethiopia
Arctic medicine. Tropical medicine
RC955-962
description Abstract Background Globally, in 2016, about 38% and 3% of all neonatal death were recorded in sub-Saharan Africa and Ethiopia, respectively. In the same year, 47 neonates out of 1000 live births were not surviving in the first 28 days of age in the Amhara region, Ethiopia. Despite the highest burden of neonatal death in the region, specific or the proximate determinants of neonatal death in the neonatal intensive care unit were not well identified. Objective This study aimed to identify the determinants of neonatal mortality at neonatal intensive care unit in Dessie Referral Hospital, Northeast Ethiopia. Methods An institution-based unmatched case-control study was conducted on neonates admitted to the neonatal intensive care unit of Dessie Referral Hospital, from January 1, 2016, to December 30, 2017. A total of 390 charts (130 cases and 260 controls) were selected by simple random sampling technique. The data were abstracted from the facility-based data abstraction form. A binary logistic regression analysis was fitted to identify the determinants of neonatal mortality. Results Pregnancy-induced hypertension (AOR = 4.57; 95% CI 1.45–14.43), prolonged rupture of membrane (AOR = 2.04; 95% CI 1.13–3.68), very low birth weight (AOR = 7.00; 95% CI 2.10–23.35), and low birth weight (AOR = 2.12; 95% CI 1.10–4.20) were identified factors. Moreover, respiratory distress syndrome (AOR = 3.61; 95% CI 1.10–12.04), perinatal asphyxia (AOR = 2.27; 95% CI 1.18–4.39), meconium aspiration syndrome (AOR = 2.35; 95% CI 1.12–4.97), and infection (AOR = 2.26; 95% CI 1.34–3.82) were also significantly associated with neonatal death. Conclusions Pregnancy-induced hypertension, prolonged rupture of membrane, low birth weight, respiratory distress syndrome, perinatal asphyxia, meconium aspiration syndrome, and infections were the major determinants of neonatal mortality. Therefore, special attention will be given to small and sick babies. Moreover, early anticipation of complications and management of mothers who had ...
format Article in Journal/Newspaper
author Abebaw Yeshambel Alemu
Getaneh Mulualem Belay
Mengistu Berhanu
Biniam Minuye
author_facet Abebaw Yeshambel Alemu
Getaneh Mulualem Belay
Mengistu Berhanu
Biniam Minuye
author_sort Abebaw Yeshambel Alemu
title Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
title_short Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
title_full Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
title_fullStr Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
title_full_unstemmed Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study
title_sort determinants of neonatal mortality at neonatal intensive care unit in northeast ethiopia: unmatched case-control study
publisher BMC
publishDate 2020
url https://doi.org/10.1186/s41182-020-00232-9
https://doaj.org/article/8883e0d08b03450b84bb0dac7e731e56
geographic Arctic
geographic_facet Arctic
genre Arctic
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op_source Tropical Medicine and Health, Vol 48, Iss 1, Pp 1-10 (2020)
op_relation http://link.springer.com/article/10.1186/s41182-020-00232-9
https://doaj.org/toc/1349-4147
doi:10.1186/s41182-020-00232-9
1349-4147
https://doaj.org/article/8883e0d08b03450b84bb0dac7e731e56
op_doi https://doi.org/10.1186/s41182-020-00232-9
container_title Tropical Medicine and Health
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