Renal tumors in children and adolescents (primary diagnostics based on a pilot study)
E.A. Karavaeva 1 , T.E. Taranushenko 2 , A.V. Morgun 2 , M.V. Borisova 1 , T.G. Kadricheva 1 , T.I. Bulava 1 , N.A. Gonchar 1 , E.A. Guseynova 1 1 Krasnoyarsk Regional Clinical Center for Maternal and Child Welfare, Krasnoyarsk, Russian Federation 2 Prof. V.F.Voino-Yasenetsky Krasnoyarsk State Medic...
Main Authors: | , , , , , , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | Russian |
Published: |
LCC «Medicine-Inform»
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/883993a2c3914f50b4ae20578fcff043 |
id |
ftdoajarticles:oai:doaj.org/article:883993a2c3914f50b4ae20578fcff043 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:883993a2c3914f50b4ae20578fcff043 2023-05-15T17:05:27+02:00 Renal tumors in children and adolescents (primary diagnostics based on a pilot study) E.A. Karavaeva T.E. Taranushenko A.V. Morgun M.V. Borisova T.G. Kadricheva T.I. Bulava N.A. Gonchar E.A. Guseynova 2021-05-01T00:00:00Z https://doaj.org/article/883993a2c3914f50b4ae20578fcff043 RU rus LCC «Medicine-Inform» http://wchjournal.com/upload/iblock/272/2729ceb02fc808ffa4988130cf2a28fa.pdf https://doaj.org/toc/2618-8430 https://doaj.org/toc/2686-7184 2618-8430 2686-7184 https://doaj.org/article/883993a2c3914f50b4ae20578fcff043 РМЖ. Мать и дитя, Vol 4, Iss 2 (2021) Pediatrics RJ1-570 Gynecology and obstetrics RG1-991 article 2021 ftdoajarticles 2022-12-31T14:31:09Z E.A. Karavaeva 1 , T.E. Taranushenko 2 , A.V. Morgun 2 , M.V. Borisova 1 , T.G. Kadricheva 1 , T.I. Bulava 1 , N.A. Gonchar 1 , E.A. Guseynova 1 1 Krasnoyarsk Regional Clinical Center for Maternal and Child Welfare, Krasnoyarsk, Russian Federation 2 Prof. V.F.Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation Aim : to assess the rate of detection and epidemiology of renal tumors in children of the Krasnoyarsk Krai and to specify some tumor characteristics during primary diagnostics. Patients and Methods: retrospective exploratory (pilot) dynamic single-center study was conducted. A group of 46 children and adolescents with renal tumors who were admitted to the Department of Hematological Malignancies for examinations and treatment in 2011–2019. All data were obtained from hospital register. Results : renal tumors account for 6.4% of hematological malignancies first diagnosed in children. 9-year primary incidence of renal tumors in children was, on average, 0.87 per 100,000 children, alternating between the increase and decrease in the detection rate. Renal tumors rank 4 th among hematological malignancies in the Krasnoyarsk Krai children. The mean age was 4.1±0.5 years. No gender differences were revealed. In a pre-hospital setting, renal tumors were suspected in 24 children (52%). The most common complaints were abdominal pains (34 patients, 74%) and enlarged abdomen (30 patients, 65%). Most renal tumors (40 out of 46) were nephroblastoma as demonstrated by histology. The distribution by prognostic risk (the likelihood of recurrence and/or other unfavorable outcome) has shown that most patients have intermediate (n=25, 54%) or high (n=19, 42%) risk. Conclusions : our findings illustrate that children with renal tumors require more attention of pediatricians in a pre-hospital setting (cancer vigilance about abdominal pains and enlarged abdomen in children) to reduce the time to diagnosis and to increase the use of renal ultrasound during checkups or in suspicious renal tumors. ... Article in Journal/Newspaper Krasnoyarsk Krai Directory of Open Access Journals: DOAJ Articles |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
Russian |
topic |
Pediatrics RJ1-570 Gynecology and obstetrics RG1-991 |
spellingShingle |
Pediatrics RJ1-570 Gynecology and obstetrics RG1-991 E.A. Karavaeva T.E. Taranushenko A.V. Morgun M.V. Borisova T.G. Kadricheva T.I. Bulava N.A. Gonchar E.A. Guseynova Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
topic_facet |
Pediatrics RJ1-570 Gynecology and obstetrics RG1-991 |
description |
E.A. Karavaeva 1 , T.E. Taranushenko 2 , A.V. Morgun 2 , M.V. Borisova 1 , T.G. Kadricheva 1 , T.I. Bulava 1 , N.A. Gonchar 1 , E.A. Guseynova 1 1 Krasnoyarsk Regional Clinical Center for Maternal and Child Welfare, Krasnoyarsk, Russian Federation 2 Prof. V.F.Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation Aim : to assess the rate of detection and epidemiology of renal tumors in children of the Krasnoyarsk Krai and to specify some tumor characteristics during primary diagnostics. Patients and Methods: retrospective exploratory (pilot) dynamic single-center study was conducted. A group of 46 children and adolescents with renal tumors who were admitted to the Department of Hematological Malignancies for examinations and treatment in 2011–2019. All data were obtained from hospital register. Results : renal tumors account for 6.4% of hematological malignancies first diagnosed in children. 9-year primary incidence of renal tumors in children was, on average, 0.87 per 100,000 children, alternating between the increase and decrease in the detection rate. Renal tumors rank 4 th among hematological malignancies in the Krasnoyarsk Krai children. The mean age was 4.1±0.5 years. No gender differences were revealed. In a pre-hospital setting, renal tumors were suspected in 24 children (52%). The most common complaints were abdominal pains (34 patients, 74%) and enlarged abdomen (30 patients, 65%). Most renal tumors (40 out of 46) were nephroblastoma as demonstrated by histology. The distribution by prognostic risk (the likelihood of recurrence and/or other unfavorable outcome) has shown that most patients have intermediate (n=25, 54%) or high (n=19, 42%) risk. Conclusions : our findings illustrate that children with renal tumors require more attention of pediatricians in a pre-hospital setting (cancer vigilance about abdominal pains and enlarged abdomen in children) to reduce the time to diagnosis and to increase the use of renal ultrasound during checkups or in suspicious renal tumors. ... |
format |
Article in Journal/Newspaper |
author |
E.A. Karavaeva T.E. Taranushenko A.V. Morgun M.V. Borisova T.G. Kadricheva T.I. Bulava N.A. Gonchar E.A. Guseynova |
author_facet |
E.A. Karavaeva T.E. Taranushenko A.V. Morgun M.V. Borisova T.G. Kadricheva T.I. Bulava N.A. Gonchar E.A. Guseynova |
author_sort |
E.A. Karavaeva |
title |
Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
title_short |
Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
title_full |
Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
title_fullStr |
Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
title_full_unstemmed |
Renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
title_sort |
renal tumors in children and adolescents (primary diagnostics based on a pilot study) |
publisher |
LCC «Medicine-Inform» |
publishDate |
2021 |
url |
https://doaj.org/article/883993a2c3914f50b4ae20578fcff043 |
genre |
Krasnoyarsk Krai |
genre_facet |
Krasnoyarsk Krai |
op_source |
РМЖ. Мать и дитя, Vol 4, Iss 2 (2021) |
op_relation |
http://wchjournal.com/upload/iblock/272/2729ceb02fc808ffa4988130cf2a28fa.pdf https://doaj.org/toc/2618-8430 https://doaj.org/toc/2686-7184 2618-8430 2686-7184 https://doaj.org/article/883993a2c3914f50b4ae20578fcff043 |
_version_ |
1766059973034377216 |