SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach
This paper describes the study population and the study design of the phase III field trial of the SPf66 vaccine in Brazil. Assessment of validity and precision principles necessary for the appropriate evaluation of the protective effect of the vaccine are discussed, as well as the results of the pr...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1996
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ftdoajarticles:oai:doaj.org/article:883924eba51f4a0abc3d24ac43ba273a 2023-05-15T15:04:11+02:00 SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach M. Urdaneta A. Prata C.J. Struchiner C.E. Tosta P. Tauil M. Boulos 1996-06-01T00:00:00Z https://doaj.org/article/883924eba51f4a0abc3d24ac43ba273a EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000300007 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/883924eba51f4a0abc3d24ac43ba273a Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 3, Pp 259-269 (1996) Vacina antimalárica Ensaio de campo SPf66 Eficácia vacinal Malaria vaccine SPf66 vaccine trial Vaccine efficacy Arctic medicine. Tropical medicine RC955-962 article 1996 ftdoajarticles 2022-12-31T02:57:30Z This paper describes the study population and the study design of the phase III field trial of the SPf66 vaccine in Brazil. Assessment of validity and precision principles necessary for the appropriate evaluation of the protective effect of the vaccine are discussed, as well as the results of the preliminary analyses of the gathered data. The analytical approach for the estimation of the protective effect of the vaccine is presented. This paper provides the conceptual framework for future publications. O presente artigo descreve a população de estudo e o desenho do ensaio de campo de fase III da vacina sintética SPf66 no Brasil. São avaliados os princípios básicos de validade e precisão, essenciais para a estimação adequada da eficácia vacinal. Os resultados da análise exploratória de dados são discutidos assim como, a abordagem analítica para a estimação da eficácia vacinal. Este trabalho fornece o marco conceitual para futuras publicações. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Vacina antimalárica Ensaio de campo SPf66 Eficácia vacinal Malaria vaccine SPf66 vaccine trial Vaccine efficacy Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Vacina antimalárica Ensaio de campo SPf66 Eficácia vacinal Malaria vaccine SPf66 vaccine trial Vaccine efficacy Arctic medicine. Tropical medicine RC955-962 M. Urdaneta A. Prata C.J. Struchiner C.E. Tosta P. Tauil M. Boulos SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
topic_facet |
Vacina antimalárica Ensaio de campo SPf66 Eficácia vacinal Malaria vaccine SPf66 vaccine trial Vaccine efficacy Arctic medicine. Tropical medicine RC955-962 |
description |
This paper describes the study population and the study design of the phase III field trial of the SPf66 vaccine in Brazil. Assessment of validity and precision principles necessary for the appropriate evaluation of the protective effect of the vaccine are discussed, as well as the results of the preliminary analyses of the gathered data. The analytical approach for the estimation of the protective effect of the vaccine is presented. This paper provides the conceptual framework for future publications. O presente artigo descreve a população de estudo e o desenho do ensaio de campo de fase III da vacina sintética SPf66 no Brasil. São avaliados os princípios básicos de validade e precisão, essenciais para a estimação adequada da eficácia vacinal. Os resultados da análise exploratória de dados são discutidos assim como, a abordagem analítica para a estimação da eficácia vacinal. Este trabalho fornece o marco conceitual para futuras publicações. |
format |
Article in Journal/Newspaper |
author |
M. Urdaneta A. Prata C.J. Struchiner C.E. Tosta P. Tauil M. Boulos |
author_facet |
M. Urdaneta A. Prata C.J. Struchiner C.E. Tosta P. Tauil M. Boulos |
author_sort |
M. Urdaneta |
title |
SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
title_short |
SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
title_full |
SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
title_fullStr |
SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
title_full_unstemmed |
SPf66 vaccine trial in Brazil: conceptual framework study design and analytical approach |
title_sort |
spf66 vaccine trial in brazil: conceptual framework study design and analytical approach |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1996 |
url |
https://doaj.org/article/883924eba51f4a0abc3d24ac43ba273a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 3, Pp 259-269 (1996) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000300007 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/883924eba51f4a0abc3d24ac43ba273a |
_version_ |
1766336001252261888 |