Susceptibility to hypoxia and breathing control changes after short-term cold exposures
Background . Hypoxia is the reduction of oxygen availability due to external or internal causes. There is large individual variability of response to hypoxia. Objective . The aim of this study was to define individual and typological features in susceptibility to hypoxia, its interrelation with hypo...
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2013
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ftdoajarticles:oai:doaj.org/article:87fae4cdad50493aa49a2af7470f9321 2023-05-15T15:14:17+02:00 Susceptibility to hypoxia and breathing control changes after short-term cold exposures Lyudmila T. Kovtun Mikhail I. Voevoda 2013-08-01T00:00:00Z https://doi.org/10.3402/ijch.v72i0.21574 https://doaj.org/article/87fae4cdad50493aa49a2af7470f9321 EN eng Taylor & Francis Group http://www.circumpolarhealthjournal.net/index.php/ijch/article/download/21574/pdf_1 https://doaj.org/toc/2242-3982 doi:10.3402/ijch.v72i0.21574 2242-3982 https://doaj.org/article/87fae4cdad50493aa49a2af7470f9321 International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-5 (2013) susceptibility to hypoxia hypercapnic ventilatory response hypoxic ventilatory response cold exposure thermoregulation Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles https://doi.org/10.3402/ijch.v72i0.21574 2022-12-31T14:18:57Z Background . Hypoxia is the reduction of oxygen availability due to external or internal causes. There is large individual variability of response to hypoxia. Objective . The aim of this study was to define individual and typological features in susceptibility to hypoxia, its interrelation with hypoxic and hypercapnic ventilatory responses (HVR and HCVR, respectively) and their changes after cold acclimation. Design . Twenty-four healthy men were tested. HVR and HCVR were measured by the rebreathing method during hypoxic and hypercapnic tests, respectively. These tests were carried out in thermoneutral conditions before and after cold exposures (nude, at 13°C, 2 h daily, for 10 days). Susceptibility to hypoxia (sSaO2) was determined as haemoglobin saturation slope during hypoxic test. Results . It was found that HVR and HCVR significantly increased and susceptibility to hypoxia (sSaO2) tended to decrease after cold acclimation. According to sSaO2 results before cold exposures, the group was divided into 3: Group 1 – with high susceptibility to hypoxia, Group 2 – medium and Group 3 – low susceptibility. Analysis of variances (MANOVA) shows the key role of susceptibility to hypoxia and cold exposures and their interrelation. Posterior analysis (Fisher LSD) showed significant difference in susceptibility to hypoxia between the groups prior to cold acclimation, while HVR and HCVR did not differ between the groups. After cold acclimation, susceptibility to hypoxia was not significantly different between the groups, while HCVR significantly increased in Groups 1 and 3, HVR significantly increased in Group 3 and HCVR, HVR did not change in Group 2. Conclusions . Short-term cold exposures caused an increase in functional reserves and improved oxygen supply of tissues in Group 1. Cold exposure hypoxia has caused energy loss in Group 3. Group 2 showed the most appropriate energy conservation reaction mode to cold exposures. No relation was found between the thermoregulation and ... Article in Journal/Newspaper Arctic Circumpolar Health International Journal of Circumpolar Health Directory of Open Access Journals: DOAJ Articles Arctic International Journal of Circumpolar Health 72 1 21574 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
susceptibility to hypoxia hypercapnic ventilatory response hypoxic ventilatory response cold exposure thermoregulation Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
susceptibility to hypoxia hypercapnic ventilatory response hypoxic ventilatory response cold exposure thermoregulation Arctic medicine. Tropical medicine RC955-962 Lyudmila T. Kovtun Mikhail I. Voevoda Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
topic_facet |
susceptibility to hypoxia hypercapnic ventilatory response hypoxic ventilatory response cold exposure thermoregulation Arctic medicine. Tropical medicine RC955-962 |
description |
Background . Hypoxia is the reduction of oxygen availability due to external or internal causes. There is large individual variability of response to hypoxia. Objective . The aim of this study was to define individual and typological features in susceptibility to hypoxia, its interrelation with hypoxic and hypercapnic ventilatory responses (HVR and HCVR, respectively) and their changes after cold acclimation. Design . Twenty-four healthy men were tested. HVR and HCVR were measured by the rebreathing method during hypoxic and hypercapnic tests, respectively. These tests were carried out in thermoneutral conditions before and after cold exposures (nude, at 13°C, 2 h daily, for 10 days). Susceptibility to hypoxia (sSaO2) was determined as haemoglobin saturation slope during hypoxic test. Results . It was found that HVR and HCVR significantly increased and susceptibility to hypoxia (sSaO2) tended to decrease after cold acclimation. According to sSaO2 results before cold exposures, the group was divided into 3: Group 1 – with high susceptibility to hypoxia, Group 2 – medium and Group 3 – low susceptibility. Analysis of variances (MANOVA) shows the key role of susceptibility to hypoxia and cold exposures and their interrelation. Posterior analysis (Fisher LSD) showed significant difference in susceptibility to hypoxia between the groups prior to cold acclimation, while HVR and HCVR did not differ between the groups. After cold acclimation, susceptibility to hypoxia was not significantly different between the groups, while HCVR significantly increased in Groups 1 and 3, HVR significantly increased in Group 3 and HCVR, HVR did not change in Group 2. Conclusions . Short-term cold exposures caused an increase in functional reserves and improved oxygen supply of tissues in Group 1. Cold exposure hypoxia has caused energy loss in Group 3. Group 2 showed the most appropriate energy conservation reaction mode to cold exposures. No relation was found between the thermoregulation and ... |
format |
Article in Journal/Newspaper |
author |
Lyudmila T. Kovtun Mikhail I. Voevoda |
author_facet |
Lyudmila T. Kovtun Mikhail I. Voevoda |
author_sort |
Lyudmila T. Kovtun |
title |
Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
title_short |
Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
title_full |
Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
title_fullStr |
Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
title_full_unstemmed |
Susceptibility to hypoxia and breathing control changes after short-term cold exposures |
title_sort |
susceptibility to hypoxia and breathing control changes after short-term cold exposures |
publisher |
Taylor & Francis Group |
publishDate |
2013 |
url |
https://doi.org/10.3402/ijch.v72i0.21574 https://doaj.org/article/87fae4cdad50493aa49a2af7470f9321 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Circumpolar Health International Journal of Circumpolar Health |
genre_facet |
Arctic Circumpolar Health International Journal of Circumpolar Health |
op_source |
International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-5 (2013) |
op_relation |
http://www.circumpolarhealthjournal.net/index.php/ijch/article/download/21574/pdf_1 https://doaj.org/toc/2242-3982 doi:10.3402/ijch.v72i0.21574 2242-3982 https://doaj.org/article/87fae4cdad50493aa49a2af7470f9321 |
op_doi |
https://doi.org/10.3402/ijch.v72i0.21574 |
container_title |
International Journal of Circumpolar Health |
container_volume |
72 |
container_issue |
1 |
container_start_page |
21574 |
_version_ |
1766344754816090112 |