Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation.
Background The liver fluke, Opisthorchis felineus, is widely distributed throughout Europe and large parts of the Russian Federation. In Western Siberia, information about opisthorchiasis is lacking although infection may lead to severe liver and bile duct diseases. We aimed to assess the current pr...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0008421 https://doaj.org/article/87417d669b864c918aefdb3368c10707 |
id |
ftdoajarticles:oai:doaj.org/article:87417d669b864c918aefdb3368c10707 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:87417d669b864c918aefdb3368c10707 2023-05-15T15:15:20+02:00 Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. Olga S Fedorova Marina M Fedotova Olga I Zvonareva Sofia V Mazeina Yulia V Kovshirina Tatiana S Sokolova Ekaterina A Golovach Anna E Kovshirina Uliana V Konovalova Ivan L Kolomeets Sergey S Gutor Vyacheslav A Petrov Jan Hattendorf Ludmila M Ogorodova Peter Odermatt 2020-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008421 https://doaj.org/article/87417d669b864c918aefdb3368c10707 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008421 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008421 https://doaj.org/article/87417d669b864c918aefdb3368c10707 PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008421 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008421 2022-12-31T05:59:59Z Background The liver fluke, Opisthorchis felineus, is widely distributed throughout Europe and large parts of the Russian Federation. In Western Siberia, information about opisthorchiasis is lacking although infection may lead to severe liver and bile duct diseases. We aimed to assess the current prevalence of O. felineus infection along with associated risk factors and morbidity in rural Western Siberia. Methods We conducted a community-based, cross-sectional study in the rural Shegarskiy district, Tomsk Oblast, Russian Federation. All household members (≥ 7 years) present on the survey day were enrolled (n = 600). Two stool samples per person were examined for helminth eggs, using PARASEP (DiaSys Ltd, UK). The number of eggs per gram (EPG) of feces was recorded. Each study participant was interviewed to determine risk factors, using a pre-tested questionnaire. An abdominal ultrasonography examination of liver and bile ducts was performed with a mobile, high resolution ultrasound device. In total, 488 persons completed assessments (two stool samples, completed questionnaires); of those, 436 individuals had an ultrasonography (US) examination. Results We observed a prevalence of O. felineus infection of 60.2%. Significant risk factors for infection were the consumption of river fish (odds ratio from adjusted analysis [aOR] 2.4, 95% CI 1.52-3.95, p<0.001), particularly stock fish (OR from multivariable analysis [mOR] 3.2, 95% CI 2.63-3.80, p<0.001), smoked fish (mOR 1.5, 95% CI 1.24-1.72, p<0.001), frozen fish (mOR 1.6, 95% CI 1.29-2.02, p<0.001), and raw fish (mOR 1.4, 95% CI 1.05-1.84, p = 0.02); and fishing activities (mOR 1.2, 95% CI 1.03-1.43, p = 0.019). Women had a higher risk of infection than men. Infection was associated positively with age and negatively with socio-economic status. The respondents' general awareness of opisthorchiasis was quite high (93.2%), but their knowledge about infection transmission and prevention was insufficient. Children aged 7-18 years old had a lower level of ... Article in Journal/Newspaper Arctic Siberia Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 6 e0008421 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Olga S Fedorova Marina M Fedotova Olga I Zvonareva Sofia V Mazeina Yulia V Kovshirina Tatiana S Sokolova Ekaterina A Golovach Anna E Kovshirina Uliana V Konovalova Ivan L Kolomeets Sergey S Gutor Vyacheslav A Petrov Jan Hattendorf Ludmila M Ogorodova Peter Odermatt Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background The liver fluke, Opisthorchis felineus, is widely distributed throughout Europe and large parts of the Russian Federation. In Western Siberia, information about opisthorchiasis is lacking although infection may lead to severe liver and bile duct diseases. We aimed to assess the current prevalence of O. felineus infection along with associated risk factors and morbidity in rural Western Siberia. Methods We conducted a community-based, cross-sectional study in the rural Shegarskiy district, Tomsk Oblast, Russian Federation. All household members (≥ 7 years) present on the survey day were enrolled (n = 600). Two stool samples per person were examined for helminth eggs, using PARASEP (DiaSys Ltd, UK). The number of eggs per gram (EPG) of feces was recorded. Each study participant was interviewed to determine risk factors, using a pre-tested questionnaire. An abdominal ultrasonography examination of liver and bile ducts was performed with a mobile, high resolution ultrasound device. In total, 488 persons completed assessments (two stool samples, completed questionnaires); of those, 436 individuals had an ultrasonography (US) examination. Results We observed a prevalence of O. felineus infection of 60.2%. Significant risk factors for infection were the consumption of river fish (odds ratio from adjusted analysis [aOR] 2.4, 95% CI 1.52-3.95, p<0.001), particularly stock fish (OR from multivariable analysis [mOR] 3.2, 95% CI 2.63-3.80, p<0.001), smoked fish (mOR 1.5, 95% CI 1.24-1.72, p<0.001), frozen fish (mOR 1.6, 95% CI 1.29-2.02, p<0.001), and raw fish (mOR 1.4, 95% CI 1.05-1.84, p = 0.02); and fishing activities (mOR 1.2, 95% CI 1.03-1.43, p = 0.019). Women had a higher risk of infection than men. Infection was associated positively with age and negatively with socio-economic status. The respondents' general awareness of opisthorchiasis was quite high (93.2%), but their knowledge about infection transmission and prevention was insufficient. Children aged 7-18 years old had a lower level of ... |
format |
Article in Journal/Newspaper |
author |
Olga S Fedorova Marina M Fedotova Olga I Zvonareva Sofia V Mazeina Yulia V Kovshirina Tatiana S Sokolova Ekaterina A Golovach Anna E Kovshirina Uliana V Konovalova Ivan L Kolomeets Sergey S Gutor Vyacheslav A Petrov Jan Hattendorf Ludmila M Ogorodova Peter Odermatt |
author_facet |
Olga S Fedorova Marina M Fedotova Olga I Zvonareva Sofia V Mazeina Yulia V Kovshirina Tatiana S Sokolova Ekaterina A Golovach Anna E Kovshirina Uliana V Konovalova Ivan L Kolomeets Sergey S Gutor Vyacheslav A Petrov Jan Hattendorf Ludmila M Ogorodova Peter Odermatt |
author_sort |
Olga S Fedorova |
title |
Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
title_short |
Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
title_full |
Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
title_fullStr |
Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
title_full_unstemmed |
Opisthorchis felineus infection, risks, and morbidity in rural Western Siberia, Russian Federation. |
title_sort |
opisthorchis felineus infection, risks, and morbidity in rural western siberia, russian federation. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008421 https://doaj.org/article/87417d669b864c918aefdb3368c10707 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Siberia |
genre_facet |
Arctic Siberia |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008421 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008421 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008421 https://doaj.org/article/87417d669b864c918aefdb3368c10707 |
op_doi |
https://doi.org/10.1371/journal.pntd.0008421 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
6 |
container_start_page |
e0008421 |
_version_ |
1766345702210797568 |