Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021
Objectives. To determine the proportion of Salmonella enterica in fecal samples of live pigs with suspected salmonellosis analyzed at the diagnostic unit of the University of Antioquia, Colombia between 2019 and 2021, and examine the serotypes and antimicrobial resistance patterns. Methods. This was...
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Pan American Health Organization
2023
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ftdoajarticles:oai:doaj.org/article:838a3d17edad4b26a9413dd6a4433b4f 2023-06-06T11:51:26+02:00 Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 Juana L. Vidal Viviana Clavijo Luis R. Castellanos Jeyashree Kathiresan Ajay M.V. Kumar Kedar Mehta Jenny J. Chaparro-Gutiérrez 2023-04-01T00:00:00Z https://doi.org/10.26633/RPSP.2023.46 https://doaj.org/article/838a3d17edad4b26a9413dd6a4433b4f EN ES PT eng spa por Pan American Health Organization https://iris.paho.org/handle/10665.2/57327 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2023.46 https://doaj.org/article/838a3d17edad4b26a9413dd6a4433b4f Revista Panamericana de Salud Pública, Vol 47, Iss 46, Pp 1-10 (2023) salmonella enterica serogroup drug resistance multiple swine colombia Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.26633/RPSP.2023.46 2023-04-16T00:30:47Z Objectives. To determine the proportion of Salmonella enterica in fecal samples of live pigs with suspected salmonellosis analyzed at the diagnostic unit of the University of Antioquia, Colombia between 2019 and 2021, and examine the serotypes and antimicrobial resistance patterns. Methods. This was a laboratory-based cross-sectional study of routine data on fecal samples received from pig farms in all nine subregions of Antioquia state, Colombia. Salmonella spp. detection at the university is done using enrichment, selective culture, and polymerase chain reaction. Serotypes were identified using the Kauffmann–White scheme and isolates were tested for antimicrobial susceptibility using broth microdilution. Results. Of 653 samples tested, 149 (23%) were positive for S. enterica. Nine serotypes were identified. The most common were Salmonella Typhimurium (56%) and its monophasic variant (35%). Resistance to ampicillin (70%) was most frequently observed, followed by ciprofloxacin (55%), and sulfamethoxazole–trimethoprim (52%). No isolates were resistant to amikacin and gentamicin. Multidrug resistance (resistance to ≥ 3 classes of antibiotics) was observed in 61 (44%) isolates. Multidrug resistance was highest in S. Typhimurium (57%) compared with the other serotypes. Serotype was associated with multidrug resistance (p = 0.01), but age of the pig and sub-region were not. Conclusions. The proportion of Salmonella spp. and the associated high levels of multidrug resistance are of concern and may indicate irrational use of antimicrobials and poor management practices in pig production systems in the region. Strengthened surveillance is needed to monitor and improve farm management practices and the use of antimicrobials in farms in Colombia. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 47 1 |
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salmonella enterica serogroup drug resistance multiple swine colombia Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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salmonella enterica serogroup drug resistance multiple swine colombia Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Juana L. Vidal Viviana Clavijo Luis R. Castellanos Jeyashree Kathiresan Ajay M.V. Kumar Kedar Mehta Jenny J. Chaparro-Gutiérrez Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
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salmonella enterica serogroup drug resistance multiple swine colombia Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Objectives. To determine the proportion of Salmonella enterica in fecal samples of live pigs with suspected salmonellosis analyzed at the diagnostic unit of the University of Antioquia, Colombia between 2019 and 2021, and examine the serotypes and antimicrobial resistance patterns. Methods. This was a laboratory-based cross-sectional study of routine data on fecal samples received from pig farms in all nine subregions of Antioquia state, Colombia. Salmonella spp. detection at the university is done using enrichment, selective culture, and polymerase chain reaction. Serotypes were identified using the Kauffmann–White scheme and isolates were tested for antimicrobial susceptibility using broth microdilution. Results. Of 653 samples tested, 149 (23%) were positive for S. enterica. Nine serotypes were identified. The most common were Salmonella Typhimurium (56%) and its monophasic variant (35%). Resistance to ampicillin (70%) was most frequently observed, followed by ciprofloxacin (55%), and sulfamethoxazole–trimethoprim (52%). No isolates were resistant to amikacin and gentamicin. Multidrug resistance (resistance to ≥ 3 classes of antibiotics) was observed in 61 (44%) isolates. Multidrug resistance was highest in S. Typhimurium (57%) compared with the other serotypes. Serotype was associated with multidrug resistance (p = 0.01), but age of the pig and sub-region were not. Conclusions. The proportion of Salmonella spp. and the associated high levels of multidrug resistance are of concern and may indicate irrational use of antimicrobials and poor management practices in pig production systems in the region. Strengthened surveillance is needed to monitor and improve farm management practices and the use of antimicrobials in farms in Colombia. |
format |
Article in Journal/Newspaper |
author |
Juana L. Vidal Viviana Clavijo Luis R. Castellanos Jeyashree Kathiresan Ajay M.V. Kumar Kedar Mehta Jenny J. Chaparro-Gutiérrez |
author_facet |
Juana L. Vidal Viviana Clavijo Luis R. Castellanos Jeyashree Kathiresan Ajay M.V. Kumar Kedar Mehta Jenny J. Chaparro-Gutiérrez |
author_sort |
Juana L. Vidal |
title |
Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
title_short |
Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
title_full |
Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
title_fullStr |
Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
title_full_unstemmed |
Multidrug-resistant Salmonella spp. in fecal samples of pigs with suspected salmonellosis in Antioquia, Colombia, 2019–2021 |
title_sort |
multidrug-resistant salmonella spp. in fecal samples of pigs with suspected salmonellosis in antioquia, colombia, 2019–2021 |
publisher |
Pan American Health Organization |
publishDate |
2023 |
url |
https://doi.org/10.26633/RPSP.2023.46 https://doaj.org/article/838a3d17edad4b26a9413dd6a4433b4f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 47, Iss 46, Pp 1-10 (2023) |
op_relation |
https://iris.paho.org/handle/10665.2/57327 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2023.46 https://doaj.org/article/838a3d17edad4b26a9413dd6a4433b4f |
op_doi |
https://doi.org/10.26633/RPSP.2023.46 |
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Revista Panamericana de Salud Pública |
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47 |
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