The burden of human African trypanosomiasis.
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in su...
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ftdoajarticles:oai:doaj.org/article:836822363ca34a05b4de58f664bd8802 2023-05-15T15:02:27+02:00 The burden of human African trypanosomiasis. Eric M Fèvre Beatrix V Wissmann Susan C Welburn Pascal Lutumba 2008-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0000333 https://doaj.org/article/836822363ca34a05b4de58f664bd8802 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC2602597?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000333 https://doaj.org/article/836822363ca34a05b4de58f664bd8802 PLoS Neglected Tropical Diseases, Vol 2, Iss 12, p e333 (2008) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2008 ftdoajarticles https://doi.org/10.1371/journal.pntd.0000333 2022-12-31T03:54:52Z Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in sub-Saharan Africa, with an emphasis on the disability-adjusted life year (DALY), data sources, and methodological issues relating to the use of this metric for assessing the burden of this disease. We highlight areas where data are lacking to properly quantify the impact of these diseases, mainly relating to quantifying under-reporting and disability associated with infection, and challenge the HAT research community to tackle the neglect in data gathering to enable better evidence-based assessments of burden using DALYs or other appropriate measures. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Daly ENVELOPE(63.761,63.761,-67.513,-67.513) PLoS Neglected Tropical Diseases 2 12 e333 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Eric M Fèvre Beatrix V Wissmann Susan C Welburn Pascal Lutumba The burden of human African trypanosomiasis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis. We review current knowledge on the burden of HAT in sub-Saharan Africa, with an emphasis on the disability-adjusted life year (DALY), data sources, and methodological issues relating to the use of this metric for assessing the burden of this disease. We highlight areas where data are lacking to properly quantify the impact of these diseases, mainly relating to quantifying under-reporting and disability associated with infection, and challenge the HAT research community to tackle the neglect in data gathering to enable better evidence-based assessments of burden using DALYs or other appropriate measures. |
format |
Article in Journal/Newspaper |
author |
Eric M Fèvre Beatrix V Wissmann Susan C Welburn Pascal Lutumba |
author_facet |
Eric M Fèvre Beatrix V Wissmann Susan C Welburn Pascal Lutumba |
author_sort |
Eric M Fèvre |
title |
The burden of human African trypanosomiasis. |
title_short |
The burden of human African trypanosomiasis. |
title_full |
The burden of human African trypanosomiasis. |
title_fullStr |
The burden of human African trypanosomiasis. |
title_full_unstemmed |
The burden of human African trypanosomiasis. |
title_sort |
burden of human african trypanosomiasis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2008 |
url |
https://doi.org/10.1371/journal.pntd.0000333 https://doaj.org/article/836822363ca34a05b4de58f664bd8802 |
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ENVELOPE(63.761,63.761,-67.513,-67.513) |
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Arctic Daly |
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Arctic Daly |
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Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 2, Iss 12, p e333 (2008) |
op_relation |
http://europepmc.org/articles/PMC2602597?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000333 https://doaj.org/article/836822363ca34a05b4de58f664bd8802 |
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https://doi.org/10.1371/journal.pntd.0000333 |
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PLoS Neglected Tropical Diseases |
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12 |
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