Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva
Arachnida is the largest class among the arthropods, constituting over 60,000 described species (spiders, mites, ticks, scorpions, palpigrades, pseudoscorpions, solpugids and harvestmen). Many accidents are caused by arachnids, especially spiders and scorpions, while some diseases can be transmitted...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:833ee1d69c0e4124bc13debf2c498575 2023-05-15T15:08:33+02:00 Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva Francielle A. Cordeiro Fernanda G. Amorim Fernando A. P. Anjolette Eliane C. Arantes 2015-09-01T00:00:00Z https://doi.org/10.1186/s40409-015-0028-5 https://doaj.org/article/833ee1d69c0e4124bc13debf2c498575 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100211&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-015-0028-5 https://doaj.org/article/833ee1d69c0e4124bc13debf2c498575 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 21, Iss 0 (2015) Arachnid toxins Scorpion venom Spider venom Tick saliva Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2015 ftdoajarticles https://doi.org/10.1186/s40409-015-0028-5 2022-12-31T14:56:08Z Arachnida is the largest class among the arthropods, constituting over 60,000 described species (spiders, mites, ticks, scorpions, palpigrades, pseudoscorpions, solpugids and harvestmen). Many accidents are caused by arachnids, especially spiders and scorpions, while some diseases can be transmitted by mites and ticks. These animals are widely dispersed in urban centers due to the large availability of shelter and food, increasing the incidence of accidents. Several protein and non-protein compounds present in the venom and saliva of these animals are responsible for symptoms observed in envenoming, exhibiting neurotoxic, dermonecrotic and hemorrhagic activities. The phylogenomic analysis from the complementary DNA of single-copy nuclear protein-coding genes shows that these animals share some common protein families known as neurotoxins, defensins, hyaluronidase, antimicrobial peptides, phospholipases and proteinases. This indicates that the venoms from these animals may present components with functional and structural similarities. Therefore, we described in this review the main components present in spider and scorpion venom as well as in tick saliva, since they have similar components. These three arachnids are responsible for many accidents of medical relevance in Brazil. Additionally, this study shows potential biotechnological applications of some components with important biological activities, which may motivate the conducting of further research studies on their action mechanisms. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 21 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arachnid toxins Scorpion venom Spider venom Tick saliva Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Arachnid toxins Scorpion venom Spider venom Tick saliva Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Francielle A. Cordeiro Fernanda G. Amorim Fernando A. P. Anjolette Eliane C. Arantes Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
topic_facet |
Arachnid toxins Scorpion venom Spider venom Tick saliva Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Arachnida is the largest class among the arthropods, constituting over 60,000 described species (spiders, mites, ticks, scorpions, palpigrades, pseudoscorpions, solpugids and harvestmen). Many accidents are caused by arachnids, especially spiders and scorpions, while some diseases can be transmitted by mites and ticks. These animals are widely dispersed in urban centers due to the large availability of shelter and food, increasing the incidence of accidents. Several protein and non-protein compounds present in the venom and saliva of these animals are responsible for symptoms observed in envenoming, exhibiting neurotoxic, dermonecrotic and hemorrhagic activities. The phylogenomic analysis from the complementary DNA of single-copy nuclear protein-coding genes shows that these animals share some common protein families known as neurotoxins, defensins, hyaluronidase, antimicrobial peptides, phospholipases and proteinases. This indicates that the venoms from these animals may present components with functional and structural similarities. Therefore, we described in this review the main components present in spider and scorpion venom as well as in tick saliva, since they have similar components. These three arachnids are responsible for many accidents of medical relevance in Brazil. Additionally, this study shows potential biotechnological applications of some components with important biological activities, which may motivate the conducting of further research studies on their action mechanisms. |
format |
Article in Journal/Newspaper |
author |
Francielle A. Cordeiro Fernanda G. Amorim Fernando A. P. Anjolette Eliane C. Arantes |
author_facet |
Francielle A. Cordeiro Fernanda G. Amorim Fernando A. P. Anjolette Eliane C. Arantes |
author_sort |
Francielle A. Cordeiro |
title |
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
title_short |
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
title_full |
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
title_fullStr |
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
title_full_unstemmed |
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva |
title_sort |
arachnids of medical importance in brazil: main active compounds present in scorpion and spider venoms and tick saliva |
publisher |
SciELO |
publishDate |
2015 |
url |
https://doi.org/10.1186/s40409-015-0028-5 https://doaj.org/article/833ee1d69c0e4124bc13debf2c498575 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 21, Iss 0 (2015) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100211&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-015-0028-5 https://doaj.org/article/833ee1d69c0e4124bc13debf2c498575 |
op_doi |
https://doi.org/10.1186/s40409-015-0028-5 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
21 |
container_issue |
1 |
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1766339897497485312 |