Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women
The association between abnormal cervical cytology and HIV infection status in women was evaluated to correlate with CD4 cell count and viral load in HIV-positive patients with the presence of low-grade (LSIL) and high-grade squamous intraepithelial lesion (HSIL). Cervical samples were collected at...
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ftdoajarticles:oai:doaj.org/article:8326cae5cdd8405ab58bd009b073e81e 2023-05-15T15:07:22+02:00 Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women Patrícia Abreu Pinheiro de Lemos Marco Túlio Antonio García-Zapata Suelene Brito do Nascimento Tavares 2012-01-01T00:00:00Z https://doi.org/10.1155/2012/869758 https://doaj.org/article/8326cae5cdd8405ab58bd009b073e81e EN eng Hindawi Limited http://dx.doi.org/10.1155/2012/869758 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2012/869758 https://doaj.org/article/8326cae5cdd8405ab58bd009b073e81e Journal of Tropical Medicine, Vol 2012 (2012) Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1155/2012/869758 2022-12-30T20:57:35Z The association between abnormal cervical cytology and HIV infection status in women was evaluated to correlate with CD4 cell count and viral load in HIV-positive patients with the presence of low-grade (LSIL) and high-grade squamous intraepithelial lesion (HSIL). Cervical samples were collected at the Tropical Disease Hospital, Maternal and Child Healthcare Hospital and at the Nascer Cidadão Maternity Hospital in Goiânia, Goiás, Brazil. An Ayre’s spatula was used to collect samples from the ectocervix and a cytology brush to collect samples from the endocervix. Of a total of 237 women, 125 were HIV positive and 112 were HIV negative. Abnormal cytology (????=21; 8.9%) was more common in the HIV positive group (????=15; 12.1%) compared to the HIV-negative group (????=6; 5.4%) (????=0.05). Cytological abnormalities were not found to be associated with immunosuppression, defined as CD4 count < 200 cells/mm3. A higher frequency was found between higher viral loads (>10,000/mm3) and the presence of abnormal cytology. Pregnant women, irrespective of whether they were HIV positive or negative, were less likely to have lesions compared to the nonpregnant women in the same groups. The higher frequency of abnormal findings in Papanicolaou cytology in HIV-positive women with higher viral loads suggests the association between preinvasive cervical lesions and human immunodeficiency. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2012 1 4 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Patrícia Abreu Pinheiro de Lemos Marco Túlio Antonio García-Zapata Suelene Brito do Nascimento Tavares Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
The association between abnormal cervical cytology and HIV infection status in women was evaluated to correlate with CD4 cell count and viral load in HIV-positive patients with the presence of low-grade (LSIL) and high-grade squamous intraepithelial lesion (HSIL). Cervical samples were collected at the Tropical Disease Hospital, Maternal and Child Healthcare Hospital and at the Nascer Cidadão Maternity Hospital in Goiânia, Goiás, Brazil. An Ayre’s spatula was used to collect samples from the ectocervix and a cytology brush to collect samples from the endocervix. Of a total of 237 women, 125 were HIV positive and 112 were HIV negative. Abnormal cytology (????=21; 8.9%) was more common in the HIV positive group (????=15; 12.1%) compared to the HIV-negative group (????=6; 5.4%) (????=0.05). Cytological abnormalities were not found to be associated with immunosuppression, defined as CD4 count < 200 cells/mm3. A higher frequency was found between higher viral loads (>10,000/mm3) and the presence of abnormal cytology. Pregnant women, irrespective of whether they were HIV positive or negative, were less likely to have lesions compared to the nonpregnant women in the same groups. The higher frequency of abnormal findings in Papanicolaou cytology in HIV-positive women with higher viral loads suggests the association between preinvasive cervical lesions and human immunodeficiency. |
format |
Article in Journal/Newspaper |
author |
Patrícia Abreu Pinheiro de Lemos Marco Túlio Antonio García-Zapata Suelene Brito do Nascimento Tavares |
author_facet |
Patrícia Abreu Pinheiro de Lemos Marco Túlio Antonio García-Zapata Suelene Brito do Nascimento Tavares |
author_sort |
Patrícia Abreu Pinheiro de Lemos |
title |
Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
title_short |
Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
title_full |
Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
title_fullStr |
Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
title_full_unstemmed |
Cervical Cytopathology in a Population of HIV-Positive and HIV-Negative Women |
title_sort |
cervical cytopathology in a population of hiv-positive and hiv-negative women |
publisher |
Hindawi Limited |
publishDate |
2012 |
url |
https://doi.org/10.1155/2012/869758 https://doaj.org/article/8326cae5cdd8405ab58bd009b073e81e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2012 (2012) |
op_relation |
http://dx.doi.org/10.1155/2012/869758 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2012/869758 https://doaj.org/article/8326cae5cdd8405ab58bd009b073e81e |
op_doi |
https://doi.org/10.1155/2012/869758 |
container_title |
Journal of Tropical Medicine |
container_volume |
2012 |
container_start_page |
1 |
op_container_end_page |
4 |
_version_ |
1766338885763203072 |