Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program.
Aedes aegypti is the most important vector of dengue fever in Brazil, where severe epidemics have recently taken place. Ae. aegypti in Brazil was the subject of an intense eradication program in the 1940s and 50s to control yellow fever. Brazil was the largest country declared free of this mosquito...
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ftdoajarticles:oai:doaj.org/article:82a1783404454febb17db916b958d949 2023-05-15T15:12:28+02:00 Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. Fernando A Monteiro Renata Schama Ademir J Martins Andrea Gloria-Soria Julia E Brown Jeffrey R Powell 2014-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003167 https://doaj.org/article/82a1783404454febb17db916b958d949 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4169244?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003167 https://doaj.org/article/82a1783404454febb17db916b958d949 PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3167 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003167 2022-12-31T15:19:02Z Aedes aegypti is the most important vector of dengue fever in Brazil, where severe epidemics have recently taken place. Ae. aegypti in Brazil was the subject of an intense eradication program in the 1940s and 50s to control yellow fever. Brazil was the largest country declared free of this mosquito by the Pan-American Health Organization in 1958. Soon after relaxation of this program, Ae. aegypti reappeared in this country, and by the early 1980s dengue fever had been reported. The aim of this study is to analyze the present-day genetic patterns of Ae. aegypti populations in Brazil.We studied the genetic variation in samples of 11 widely spread populations of Ae. aegypti in Brazil based on 12 well-established microsatellite loci. Our principal finding is that present-day Brazilian Ae. aegypti populations form two distinct groups, one in the northwest and one in the southeast of the country. These two groups have genetic affinities to northern South American countries and the Caribbean, respectively. This is consistent with what has been reported for other genetic markers such as mitochondrial DNA and allele frequencies at the insecticide resistance gene, kdr.We conclude that the genetic patterns in present day populations of Ae. aegypti in Brazil are more consistent with a complete eradication of the species in the recent past followed by re-colonization, rather than the alternative possibility of expansion from residual pockets of refugia. At least two colonizations are likely to have taken place, one from northern South American countries (e.g., Venezuela) that founded the northwestern group, and one from the Caribbean that founded the southeastern group. The proposed source areas were never declared free of Ae. aegypti. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 9 e3167 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Fernando A Monteiro Renata Schama Ademir J Martins Andrea Gloria-Soria Julia E Brown Jeffrey R Powell Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Aedes aegypti is the most important vector of dengue fever in Brazil, where severe epidemics have recently taken place. Ae. aegypti in Brazil was the subject of an intense eradication program in the 1940s and 50s to control yellow fever. Brazil was the largest country declared free of this mosquito by the Pan-American Health Organization in 1958. Soon after relaxation of this program, Ae. aegypti reappeared in this country, and by the early 1980s dengue fever had been reported. The aim of this study is to analyze the present-day genetic patterns of Ae. aegypti populations in Brazil.We studied the genetic variation in samples of 11 widely spread populations of Ae. aegypti in Brazil based on 12 well-established microsatellite loci. Our principal finding is that present-day Brazilian Ae. aegypti populations form two distinct groups, one in the northwest and one in the southeast of the country. These two groups have genetic affinities to northern South American countries and the Caribbean, respectively. This is consistent with what has been reported for other genetic markers such as mitochondrial DNA and allele frequencies at the insecticide resistance gene, kdr.We conclude that the genetic patterns in present day populations of Ae. aegypti in Brazil are more consistent with a complete eradication of the species in the recent past followed by re-colonization, rather than the alternative possibility of expansion from residual pockets of refugia. At least two colonizations are likely to have taken place, one from northern South American countries (e.g., Venezuela) that founded the northwestern group, and one from the Caribbean that founded the southeastern group. The proposed source areas were never declared free of Ae. aegypti. |
format |
Article in Journal/Newspaper |
author |
Fernando A Monteiro Renata Schama Ademir J Martins Andrea Gloria-Soria Julia E Brown Jeffrey R Powell |
author_facet |
Fernando A Monteiro Renata Schama Ademir J Martins Andrea Gloria-Soria Julia E Brown Jeffrey R Powell |
author_sort |
Fernando A Monteiro |
title |
Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
title_short |
Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
title_full |
Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
title_fullStr |
Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
title_full_unstemmed |
Genetic diversity of Brazilian Aedes aegypti: patterns following an eradication program. |
title_sort |
genetic diversity of brazilian aedes aegypti: patterns following an eradication program. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0003167 https://doaj.org/article/82a1783404454febb17db916b958d949 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3167 (2014) |
op_relation |
http://europepmc.org/articles/PMC4169244?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003167 https://doaj.org/article/82a1783404454febb17db916b958d949 |
op_doi |
https://doi.org/10.1371/journal.pntd.0003167 |
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PLoS Neglected Tropical Diseases |
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8 |
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9 |
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e3167 |
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