Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations
The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a half. An unprecedented number of people around the world have been infected with SARS-CoV-2, the etiological agent of COVID-19. Despite the fact that the mortality rate for COVID-19 is relatively low,...
Published in: | Viruses |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI AG
2021
|
Subjects: | |
Online Access: | https://doi.org/10.3390/v13061029 https://doaj.org/article/81c994f74b8740f8afb71806ac084551 |
id |
ftdoajarticles:oai:doaj.org/article:81c994f74b8740f8afb71806ac084551 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:81c994f74b8740f8afb71806ac084551 2023-05-15T17:46:05+02:00 Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations Anna Gladkikh Anna Dolgova Vladimir Dedkov Valeriya Sbarzaglia Olga Kanaeva Anna Popova Areg Totolian 2021-05-01T00:00:00Z https://doi.org/10.3390/v13061029 https://doaj.org/article/81c994f74b8740f8afb71806ac084551 EN eng MDPI AG https://www.mdpi.com/1999-4915/13/6/1029 https://doaj.org/toc/1999-4915 doi:10.3390/v13061029 1999-4915 https://doaj.org/article/81c994f74b8740f8afb71806ac084551 Viruses, Vol 13, Iss 1029, p 1029 (2021) SARS-CoV-2 COVID-19 variants of concern northwest (NW) variant Russia Microbiology QR1-502 article 2021 ftdoajarticles https://doi.org/10.3390/v13061029 2022-12-31T13:14:25Z The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a half. An unprecedented number of people around the world have been infected with SARS-CoV-2, the etiological agent of COVID-19. Despite the fact that the mortality rate for COVID-19 is relatively low, the total number of deaths has currently already reached more than three million and continues to increase due to high incidence. Since the beginning of the pandemic, a large number of sequences have been obtained and many genetic variants have been identified. Some of them bear significant mutations that affect biological properties of the virus. These genetic variants, currently Variants of Concern (VoC), include the so-called United Kingdom variant (20I/501Y), the Brazilian variant (20J/501Y.V3), and the South African variant (20H/501Y.V2). We describe here a novel SARS-CoV-2 variant with distinct spike protein mutations, first obtained at the end of January 2021 in northwest Russia. Therefore, it is necessary to pay attention to the dynamics of its spread among patients with COVID-19, as well as to study in detail its biological properties Article in Journal/Newspaper Northwest Russia Directory of Open Access Journals: DOAJ Articles Viruses 13 6 1029 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
SARS-CoV-2 COVID-19 variants of concern northwest (NW) variant Russia Microbiology QR1-502 |
spellingShingle |
SARS-CoV-2 COVID-19 variants of concern northwest (NW) variant Russia Microbiology QR1-502 Anna Gladkikh Anna Dolgova Vladimir Dedkov Valeriya Sbarzaglia Olga Kanaeva Anna Popova Areg Totolian Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
topic_facet |
SARS-CoV-2 COVID-19 variants of concern northwest (NW) variant Russia Microbiology QR1-502 |
description |
The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a half. An unprecedented number of people around the world have been infected with SARS-CoV-2, the etiological agent of COVID-19. Despite the fact that the mortality rate for COVID-19 is relatively low, the total number of deaths has currently already reached more than three million and continues to increase due to high incidence. Since the beginning of the pandemic, a large number of sequences have been obtained and many genetic variants have been identified. Some of them bear significant mutations that affect biological properties of the virus. These genetic variants, currently Variants of Concern (VoC), include the so-called United Kingdom variant (20I/501Y), the Brazilian variant (20J/501Y.V3), and the South African variant (20H/501Y.V2). We describe here a novel SARS-CoV-2 variant with distinct spike protein mutations, first obtained at the end of January 2021 in northwest Russia. Therefore, it is necessary to pay attention to the dynamics of its spread among patients with COVID-19, as well as to study in detail its biological properties |
format |
Article in Journal/Newspaper |
author |
Anna Gladkikh Anna Dolgova Vladimir Dedkov Valeriya Sbarzaglia Olga Kanaeva Anna Popova Areg Totolian |
author_facet |
Anna Gladkikh Anna Dolgova Vladimir Dedkov Valeriya Sbarzaglia Olga Kanaeva Anna Popova Areg Totolian |
author_sort |
Anna Gladkikh |
title |
Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
title_short |
Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
title_full |
Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
title_fullStr |
Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
title_full_unstemmed |
Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations |
title_sort |
characterization of a novel sars-cov-2 genetic variant with distinct spike protein mutations |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doi.org/10.3390/v13061029 https://doaj.org/article/81c994f74b8740f8afb71806ac084551 |
genre |
Northwest Russia |
genre_facet |
Northwest Russia |
op_source |
Viruses, Vol 13, Iss 1029, p 1029 (2021) |
op_relation |
https://www.mdpi.com/1999-4915/13/6/1029 https://doaj.org/toc/1999-4915 doi:10.3390/v13061029 1999-4915 https://doaj.org/article/81c994f74b8740f8afb71806ac084551 |
op_doi |
https://doi.org/10.3390/v13061029 |
container_title |
Viruses |
container_volume |
13 |
container_issue |
6 |
container_start_page |
1029 |
_version_ |
1766149439319179264 |