Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study
Abstract Background Malaria remains a serious epidemic threat in Mpumalanga Province. In order to appropriately target interventions to achieve substantial reduction in the burden of malaria and ultimately eliminate the disease, there is a need to track progress of malaria control efforts by assessi...
Published in: | Malaria Journal |
---|---|
Main Authors: | , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2012
|
Subjects: | |
Online Access: | https://doi.org/10.1186/1475-2875-11-19 https://doaj.org/article/8189489d284842f2b9654d98e18fb76d |
id |
ftdoajarticles:oai:doaj.org/article:8189489d284842f2b9654d98e18fb76d |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:8189489d284842f2b9654d98e18fb76d 2023-05-15T15:18:16+02:00 Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study Ngomane Lindokuhle de Jager Christiaan 2012-01-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-19 https://doaj.org/article/8189489d284842f2b9654d98e18fb76d EN eng BMC http://www.malariajournal.com/content/11/1/19 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-19 1475-2875 https://doaj.org/article/8189489d284842f2b9654d98e18fb76d Malaria Journal, Vol 11, Iss 1, p 19 (2012) Malaria Morbidity Mortality Incidence rate Case fatality rate Vector control Indoor residual spraying Climate Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-19 2022-12-30T21:44:59Z Abstract Background Malaria remains a serious epidemic threat in Mpumalanga Province. In order to appropriately target interventions to achieve substantial reduction in the burden of malaria and ultimately eliminate the disease, there is a need to track progress of malaria control efforts by assessing the time trends and evaluating the impact of current control interventions. This study aimed to assess the changes in the burden of malaria in Mpumalanga Province during the past eight malaria seasons (2001/02 to 2008/09) and whether indoor residual spraying (IRS) and climate variability had an effect on these changes. Methods This is a descriptive retrospective study based on the analysis of secondary malaria surveillance data (cases and deaths) in Mpumalanga Province. Data were extracted from the Integrated Malaria Information System. Time series model (Autoregressive Integrated Moving Average) was used to assess the association between climate and malaria. Results Within the study period, a total of 35,191 cases and 164 deaths due to malaria were notified in Mpumalanga Province. There was a significant decrease in the incidence of malaria from 385 in 2001/02 to 50 cases per 100,000 population in 2008/09 ( P < 0.005). The incidence and case fatality (CFR) rates for the study period were 134 cases per 100,000 and 0.54%, respectively. Mortality due to malaria was lower in infants and children (CFR < 0.5%) and higher in those >65 years, with the mean CFR of 2.1% as compared to the national target of 0.5%. A distinct seasonal transmission pattern was found to be significantly related to changes in rainfall patterns ( P = 0.007). A notable decline in malaria case notification was observed following apparent scale-up of IRS coverage from 2006/07 to 2008/09 malaria seasons. Conclusions Mpumalanga Province has achieved the goal of reducing malaria morbidity and mortality by over 70%, partly as a result of scale-up of IRS intervention in combination with other control strategies. These results highlight the need ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Malaria Morbidity Mortality Incidence rate Case fatality rate Vector control Indoor residual spraying Climate Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Malaria Morbidity Mortality Incidence rate Case fatality rate Vector control Indoor residual spraying Climate Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Ngomane Lindokuhle de Jager Christiaan Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
topic_facet |
Malaria Morbidity Mortality Incidence rate Case fatality rate Vector control Indoor residual spraying Climate Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria remains a serious epidemic threat in Mpumalanga Province. In order to appropriately target interventions to achieve substantial reduction in the burden of malaria and ultimately eliminate the disease, there is a need to track progress of malaria control efforts by assessing the time trends and evaluating the impact of current control interventions. This study aimed to assess the changes in the burden of malaria in Mpumalanga Province during the past eight malaria seasons (2001/02 to 2008/09) and whether indoor residual spraying (IRS) and climate variability had an effect on these changes. Methods This is a descriptive retrospective study based on the analysis of secondary malaria surveillance data (cases and deaths) in Mpumalanga Province. Data were extracted from the Integrated Malaria Information System. Time series model (Autoregressive Integrated Moving Average) was used to assess the association between climate and malaria. Results Within the study period, a total of 35,191 cases and 164 deaths due to malaria were notified in Mpumalanga Province. There was a significant decrease in the incidence of malaria from 385 in 2001/02 to 50 cases per 100,000 population in 2008/09 ( P < 0.005). The incidence and case fatality (CFR) rates for the study period were 134 cases per 100,000 and 0.54%, respectively. Mortality due to malaria was lower in infants and children (CFR < 0.5%) and higher in those >65 years, with the mean CFR of 2.1% as compared to the national target of 0.5%. A distinct seasonal transmission pattern was found to be significantly related to changes in rainfall patterns ( P = 0.007). A notable decline in malaria case notification was observed following apparent scale-up of IRS coverage from 2006/07 to 2008/09 malaria seasons. Conclusions Mpumalanga Province has achieved the goal of reducing malaria morbidity and mortality by over 70%, partly as a result of scale-up of IRS intervention in combination with other control strategies. These results highlight the need ... |
format |
Article in Journal/Newspaper |
author |
Ngomane Lindokuhle de Jager Christiaan |
author_facet |
Ngomane Lindokuhle de Jager Christiaan |
author_sort |
Ngomane Lindokuhle |
title |
Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
title_short |
Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
title_full |
Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
title_fullStr |
Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
title_full_unstemmed |
Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study |
title_sort |
changes in malaria morbidity and mortality in mpumalanga province, south africa (2001- 2009): a retrospective study |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-19 https://doaj.org/article/8189489d284842f2b9654d98e18fb76d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 19 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/19 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-19 1475-2875 https://doaj.org/article/8189489d284842f2b9654d98e18fb76d |
op_doi |
https://doi.org/10.1186/1475-2875-11-19 |
container_title |
Malaria Journal |
container_volume |
11 |
container_issue |
1 |
_version_ |
1766348474765279232 |