Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency
INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine rec...
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ftdoajarticles:oai:doaj.org/article:81283c12d0144a02b38404b4c8c8e406 2023-05-15T15:01:29+02:00 Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency Maria Teresa Nascimento Silva Vlaudia Assis Costa Teobaldo Gonzaga Realço Pereira Iana Rafaela Fernandes Sales Silvana Ferreira da Silva Maria Amélia Vieira Maciel Elizabeth Malagueño Valdênia Maria Oliveira Souza 2012-12-01T00:00:00Z https://doi.org/10.1590/S0037-86822012000600021 https://doaj.org/article/81283c12d0144a02b38404b4c8c8e406 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000600021 https://doaj.org/article/81283c12d0144a02b38404b4c8c8e406 Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 6, Pp 761-763 (2012) Dermatite atópica Ascaris lumbricoides Receptores CCR4 e CXCR3 Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1590/S0037-86822012000600021 2022-12-30T21:50:08Z INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 45 6 761 763 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Dermatite atópica Ascaris lumbricoides Receptores CCR4 e CXCR3 Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Dermatite atópica Ascaris lumbricoides Receptores CCR4 e CXCR3 Arctic medicine. Tropical medicine RC955-962 Maria Teresa Nascimento Silva Vlaudia Assis Costa Teobaldo Gonzaga Realço Pereira Iana Rafaela Fernandes Sales Silvana Ferreira da Silva Maria Amélia Vieira Maciel Elizabeth Malagueño Valdênia Maria Oliveira Souza Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
topic_facet |
Dermatite atópica Ascaris lumbricoides Receptores CCR4 e CXCR3 Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients. |
format |
Article in Journal/Newspaper |
author |
Maria Teresa Nascimento Silva Vlaudia Assis Costa Teobaldo Gonzaga Realço Pereira Iana Rafaela Fernandes Sales Silvana Ferreira da Silva Maria Amélia Vieira Maciel Elizabeth Malagueño Valdênia Maria Oliveira Souza |
author_facet |
Maria Teresa Nascimento Silva Vlaudia Assis Costa Teobaldo Gonzaga Realço Pereira Iana Rafaela Fernandes Sales Silvana Ferreira da Silva Maria Amélia Vieira Maciel Elizabeth Malagueño Valdênia Maria Oliveira Souza |
author_sort |
Maria Teresa Nascimento Silva |
title |
Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
title_short |
Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
title_full |
Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
title_fullStr |
Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
title_full_unstemmed |
Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency |
title_sort |
severity of atopic dermatitis and ascaris lumbricoides infection: an evaluation of ccr4+ and cxcr3+ helper t cell frequency |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2012 |
url |
https://doi.org/10.1590/S0037-86822012000600021 https://doaj.org/article/81283c12d0144a02b38404b4c8c8e406 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 6, Pp 761-763 (2012) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600021&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000600021 https://doaj.org/article/81283c12d0144a02b38404b4c8c8e406 |
op_doi |
https://doi.org/10.1590/S0037-86822012000600021 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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45 |
container_issue |
6 |
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761 |
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763 |
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