Temporal association between the isolation of Sabin-related poliovirus vaccine strains and the Guillain-Barré syndrome

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: F. Friedrich, A. M. B. Filippis, H. G. Schatzmayr
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1996
• Subjects: Sabin vaccine; Poliovirus; Guillain-Barré syndrome; vaccine-associated; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Barré
• Online Access: https://doi.org/10.1590/S0036-46651996000100010; https://doaj.org/article/80c01bb9c9ff4faa8f7b31f4bc5eb817

Thirty eight paralysis cases classified as Guillain-Barré syndrome (GBS) in Brazil were analysed. In all these cases Sabin-related poliovirus vaccine strains were isolated. In most of the cases the last vaccine dose was given months or years before the onset of GBS, suggesting a persistent infection...