Exploring malaria vector diversity on the Amazon Frontier
Abstract Background Deforestation in the Amazon and the social vulnerability of its settler communities has been associated with increased malaria incidence. The feeding biology of the most important malaria vectors in the region, notably Nyssorhynchus darlingi, compounds efforts to control vectors...
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ftdoajarticles:oai:doaj.org/article:804383bed46a437a88b37372c6c5119e 2023-05-15T15:12:31+02:00 Exploring malaria vector diversity on the Amazon Frontier Brian P. Bourke Jan E. Conn Tatiane M. P. de Oliveira Leonardo S. M. Chaves Eduardo S. Bergo Gabriel Z. Laporta Maria A. M. Sallum 2018-09-01T00:00:00Z https://doi.org/10.1186/s12936-018-2483-2 https://doaj.org/article/804383bed46a437a88b37372c6c5119e EN eng BMC http://link.springer.com/article/10.1186/s12936-018-2483-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-018-2483-2 1475-2875 https://doaj.org/article/804383bed46a437a88b37372c6c5119e Malaria Journal, Vol 17, Iss 1, Pp 1-17 (2018) Malaria Species discovery Mosquito Anophelinae Amazon Deforestation Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2018 ftdoajarticles https://doi.org/10.1186/s12936-018-2483-2 2022-12-31T05:43:56Z Abstract Background Deforestation in the Amazon and the social vulnerability of its settler communities has been associated with increased malaria incidence. The feeding biology of the most important malaria vectors in the region, notably Nyssorhynchus darlingi, compounds efforts to control vectors and reduce transmission of what has become known as “Frontier Malaria”. Exploring Anophelinae mosquito diversity is fundamental to understanding the species responsible for transmission and developing appropriate management and intervention strategies for malaria control in the Amazon River basin. Methods This study describes Anophelinae mosquito diversity from settler communities affected by Frontier Malaria in the states of Acre, Amazonas and Rondônia by analysing COI gene data using cluster and tree-based species delimitation approaches. Results In total, 270 specimens from collection sites were sequenced and these were combined with 151 reference (GenBank) sequences in the analysis to assist in species identification. Conservative estimates found that the number of species collected at these sites was between 23 (mPTP partition) and 27 (strict ABGD partition) species, up to 13 of which appeared to be new. Nyssorhynchus triannulatus and Nyssorhynchus braziliensis displayed exceptional levels of intraspecific genetic diversity but there was little to no support for putative species complex status. Conclusions This study demonstrates that Anophelinae mosquito diversity continues to be underestimated in poorly sampled areas where frontier malaria is a major public health concern. The findings will help shape future studies of vector incrimination and transmission dynamics in these areas and support efforts to develop more effective vector control and transmission reduction strategies in settler communities in the Amazon River basin. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 17 1 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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language |
English |
topic |
Malaria Species discovery Mosquito Anophelinae Amazon Deforestation Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Malaria Species discovery Mosquito Anophelinae Amazon Deforestation Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Brian P. Bourke Jan E. Conn Tatiane M. P. de Oliveira Leonardo S. M. Chaves Eduardo S. Bergo Gabriel Z. Laporta Maria A. M. Sallum Exploring malaria vector diversity on the Amazon Frontier |
topic_facet |
Malaria Species discovery Mosquito Anophelinae Amazon Deforestation Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Deforestation in the Amazon and the social vulnerability of its settler communities has been associated with increased malaria incidence. The feeding biology of the most important malaria vectors in the region, notably Nyssorhynchus darlingi, compounds efforts to control vectors and reduce transmission of what has become known as “Frontier Malaria”. Exploring Anophelinae mosquito diversity is fundamental to understanding the species responsible for transmission and developing appropriate management and intervention strategies for malaria control in the Amazon River basin. Methods This study describes Anophelinae mosquito diversity from settler communities affected by Frontier Malaria in the states of Acre, Amazonas and Rondônia by analysing COI gene data using cluster and tree-based species delimitation approaches. Results In total, 270 specimens from collection sites were sequenced and these were combined with 151 reference (GenBank) sequences in the analysis to assist in species identification. Conservative estimates found that the number of species collected at these sites was between 23 (mPTP partition) and 27 (strict ABGD partition) species, up to 13 of which appeared to be new. Nyssorhynchus triannulatus and Nyssorhynchus braziliensis displayed exceptional levels of intraspecific genetic diversity but there was little to no support for putative species complex status. Conclusions This study demonstrates that Anophelinae mosquito diversity continues to be underestimated in poorly sampled areas where frontier malaria is a major public health concern. The findings will help shape future studies of vector incrimination and transmission dynamics in these areas and support efforts to develop more effective vector control and transmission reduction strategies in settler communities in the Amazon River basin. |
format |
Article in Journal/Newspaper |
author |
Brian P. Bourke Jan E. Conn Tatiane M. P. de Oliveira Leonardo S. M. Chaves Eduardo S. Bergo Gabriel Z. Laporta Maria A. M. Sallum |
author_facet |
Brian P. Bourke Jan E. Conn Tatiane M. P. de Oliveira Leonardo S. M. Chaves Eduardo S. Bergo Gabriel Z. Laporta Maria A. M. Sallum |
author_sort |
Brian P. Bourke |
title |
Exploring malaria vector diversity on the Amazon Frontier |
title_short |
Exploring malaria vector diversity on the Amazon Frontier |
title_full |
Exploring malaria vector diversity on the Amazon Frontier |
title_fullStr |
Exploring malaria vector diversity on the Amazon Frontier |
title_full_unstemmed |
Exploring malaria vector diversity on the Amazon Frontier |
title_sort |
exploring malaria vector diversity on the amazon frontier |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s12936-018-2483-2 https://doaj.org/article/804383bed46a437a88b37372c6c5119e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 17, Iss 1, Pp 1-17 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s12936-018-2483-2 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-018-2483-2 1475-2875 https://doaj.org/article/804383bed46a437a88b37372c6c5119e |
op_doi |
https://doi.org/10.1186/s12936-018-2483-2 |
container_title |
Malaria Journal |
container_volume |
17 |
container_issue |
1 |
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1766343190078554112 |