A multi-species bait for Chagas disease vectors.
BACKGROUND: Triatomine bugs are the insect vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. These insects are known to aggregate inside shelters during daylight hours and it has been demonstrated that within shelters, the aggregation is induced by volatiles emitted from bug fec...
Published in: | PLoS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:7fbdeb3227064dacae47a3bb3a009fc5 2023-05-15T15:07:08+02:00 A multi-species bait for Chagas disease vectors. Theo Mota Ana C R Vitta Alicia N Lorenzo-Figueiras Carla P Barezani Carlos L Zani Claudio R Lazzari Liléia Diotaiuti Lynne Jeffares Björn Bohman Marcelo G Lorenzo 2014-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002677 https://doaj.org/article/7fbdeb3227064dacae47a3bb3a009fc5 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3937276?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002677 https://doaj.org/article/7fbdeb3227064dacae47a3bb3a009fc5 PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2677 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002677 2022-12-31T00:47:58Z BACKGROUND: Triatomine bugs are the insect vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. These insects are known to aggregate inside shelters during daylight hours and it has been demonstrated that within shelters, the aggregation is induced by volatiles emitted from bug feces. These signals promote inter-species aggregation among most species studied, but the chemical composition is unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the present work, feces from larvae of the three species were obtained and volatile compounds were identified by solid phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS). We identified five compounds, all present in feces of all of the three species: Triatoma infestans, Panstrongylus megistus and Triatoma brasiliensis. These substances were tested for attractivity and ability to recruit insects into shelters. Behaviorally active doses of the five substances were obtained for all three triatomine species. The bugs were significantly attracted to shelters baited with blends of 160 ng or 1.6 µg of each substance. CONCLUSIONS/SIGNIFICANCE: Common compounds were found in the feces of vectors of Chagas disease that actively recruited insects into shelters, which suggests that this blend of compounds could be used for the development of baits for early detection of reinfestation with triatomine bugs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 2 e2677 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Theo Mota Ana C R Vitta Alicia N Lorenzo-Figueiras Carla P Barezani Carlos L Zani Claudio R Lazzari Liléia Diotaiuti Lynne Jeffares Björn Bohman Marcelo G Lorenzo A multi-species bait for Chagas disease vectors. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND: Triatomine bugs are the insect vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. These insects are known to aggregate inside shelters during daylight hours and it has been demonstrated that within shelters, the aggregation is induced by volatiles emitted from bug feces. These signals promote inter-species aggregation among most species studied, but the chemical composition is unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the present work, feces from larvae of the three species were obtained and volatile compounds were identified by solid phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS). We identified five compounds, all present in feces of all of the three species: Triatoma infestans, Panstrongylus megistus and Triatoma brasiliensis. These substances were tested for attractivity and ability to recruit insects into shelters. Behaviorally active doses of the five substances were obtained for all three triatomine species. The bugs were significantly attracted to shelters baited with blends of 160 ng or 1.6 µg of each substance. CONCLUSIONS/SIGNIFICANCE: Common compounds were found in the feces of vectors of Chagas disease that actively recruited insects into shelters, which suggests that this blend of compounds could be used for the development of baits for early detection of reinfestation with triatomine bugs. |
format |
Article in Journal/Newspaper |
author |
Theo Mota Ana C R Vitta Alicia N Lorenzo-Figueiras Carla P Barezani Carlos L Zani Claudio R Lazzari Liléia Diotaiuti Lynne Jeffares Björn Bohman Marcelo G Lorenzo |
author_facet |
Theo Mota Ana C R Vitta Alicia N Lorenzo-Figueiras Carla P Barezani Carlos L Zani Claudio R Lazzari Liléia Diotaiuti Lynne Jeffares Björn Bohman Marcelo G Lorenzo |
author_sort |
Theo Mota |
title |
A multi-species bait for Chagas disease vectors. |
title_short |
A multi-species bait for Chagas disease vectors. |
title_full |
A multi-species bait for Chagas disease vectors. |
title_fullStr |
A multi-species bait for Chagas disease vectors. |
title_full_unstemmed |
A multi-species bait for Chagas disease vectors. |
title_sort |
multi-species bait for chagas disease vectors. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0002677 https://doaj.org/article/7fbdeb3227064dacae47a3bb3a009fc5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2677 (2014) |
op_relation |
http://europepmc.org/articles/PMC3937276?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002677 https://doaj.org/article/7fbdeb3227064dacae47a3bb3a009fc5 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002677 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
8 |
container_issue |
2 |
container_start_page |
e2677 |
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1766338700756647936 |