Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects

Objectives: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. Material and Methods:Forty adult patients were recruited with at...

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Main Authors: Iván Mandel, Sándor Farkasdi, Gábor Varga, Ákos Károly Nagy
Format: Article in Journal/Newspaper
Language:English
Croatian
Published: University of Zagreb. School of Dental Medicine 2020
Subjects:
Online Access:https://doaj.org/article/7f5e88ebbf2e4a52bb3f7a4ed0cb4d50
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spelling ftdoajarticles:oai:doaj.org/article:7f5e88ebbf2e4a52bb3f7a4ed0cb4d50 2023-05-15T17:24:34+02:00 Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects Iván Mandel Sándor Farkasdi Gábor Varga Ákos Károly Nagy 2020-01-01T00:00:00Z https://doaj.org/article/7f5e88ebbf2e4a52bb3f7a4ed0cb4d50 EN HR eng hrv University of Zagreb. School of Dental Medicine https://hrcak.srce.hr/file/354608 https://doaj.org/toc/0001-7019 https://doaj.org/toc/1846-0410 0001-7019 1846-0410 https://doaj.org/article/7f5e88ebbf2e4a52bb3f7a4ed0cb4d50 Acta Stomatologica Croatica, Vol 54, Iss 3, Pp 227-237 (2020) Gingival Recession Interdental Papilla Hyaluronic Acid Dentistry RK1-715 article 2020 ftdoajarticles 2022-12-31T07:05:53Z Objectives: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. Material and Methods:Forty adult patients were recruited with at least two upper and two lower interdental papilla defects in the front region between canine teeth. According to the Nordland-Tarnow classification of papillary defects, both Class I and Class II recessions were included in the investigation. Patients were randomly assigned to experimental groups to receive single injections of two different hyaluronic acid products, either Flex Barrier or Revident. The untreat-ed sites served as controls. Photographs were taken before and immediately after the treatment, and again after one week and one month. To determine the size of the black triangles, Image J software was used. For statistical analysis, a mixed-design ANOVA was applied. Results:Both Flex Barrier and Revident significantly decreased the size of the treated defects immediately after the treatment and also one week later (p<0.001). The beneficial effect of Revident lasted longer than Flex Barrier as it remained significant even after one month in Revident-treated patients, however, not in the Flex Barrier-treated group. Furthermore, Nordland-Tarnow Class I lesions generally showed a greater improve-ment than Class II lesions. Conclusion: In this proof-of-concept, randomized clinical trial we have demonstrated the clinical applicability of both Flex Barrier and Revident, although Revident gave longer-lasting improvements than Flex Barrier. Further trials are needed to optimize multiple-application protocols for treating gingival black triangles. Article in Journal/Newspaper Nordland Nordland Nordland Directory of Open Access Journals: DOAJ Articles
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
Croatian
topic Gingival Recession
Interdental Papilla
Hyaluronic Acid
Dentistry
RK1-715
spellingShingle Gingival Recession
Interdental Papilla
Hyaluronic Acid
Dentistry
RK1-715
Iván Mandel
Sándor Farkasdi
Gábor Varga
Ákos Károly Nagy
Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
topic_facet Gingival Recession
Interdental Papilla
Hyaluronic Acid
Dentistry
RK1-715
description Objectives: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. Material and Methods:Forty adult patients were recruited with at least two upper and two lower interdental papilla defects in the front region between canine teeth. According to the Nordland-Tarnow classification of papillary defects, both Class I and Class II recessions were included in the investigation. Patients were randomly assigned to experimental groups to receive single injections of two different hyaluronic acid products, either Flex Barrier or Revident. The untreat-ed sites served as controls. Photographs were taken before and immediately after the treatment, and again after one week and one month. To determine the size of the black triangles, Image J software was used. For statistical analysis, a mixed-design ANOVA was applied. Results:Both Flex Barrier and Revident significantly decreased the size of the treated defects immediately after the treatment and also one week later (p<0.001). The beneficial effect of Revident lasted longer than Flex Barrier as it remained significant even after one month in Revident-treated patients, however, not in the Flex Barrier-treated group. Furthermore, Nordland-Tarnow Class I lesions generally showed a greater improve-ment than Class II lesions. Conclusion: In this proof-of-concept, randomized clinical trial we have demonstrated the clinical applicability of both Flex Barrier and Revident, although Revident gave longer-lasting improvements than Flex Barrier. Further trials are needed to optimize multiple-application protocols for treating gingival black triangles.
format Article in Journal/Newspaper
author Iván Mandel
Sándor Farkasdi
Gábor Varga
Ákos Károly Nagy
author_facet Iván Mandel
Sándor Farkasdi
Gábor Varga
Ákos Károly Nagy
author_sort Iván Mandel
title Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
title_short Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
title_full Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
title_fullStr Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
title_full_unstemmed Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
title_sort comparative evaluation of two hyaluronic acid gel products for the treatment of interdental papillary defects
publisher University of Zagreb. School of Dental Medicine
publishDate 2020
url https://doaj.org/article/7f5e88ebbf2e4a52bb3f7a4ed0cb4d50
genre Nordland
Nordland
Nordland
genre_facet Nordland
Nordland
Nordland
op_source Acta Stomatologica Croatica, Vol 54, Iss 3, Pp 227-237 (2020)
op_relation https://hrcak.srce.hr/file/354608
https://doaj.org/toc/0001-7019
https://doaj.org/toc/1846-0410
0001-7019
1846-0410
https://doaj.org/article/7f5e88ebbf2e4a52bb3f7a4ed0cb4d50
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