Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico
Background The combination of Wolbachia-based incompatible insect technique (IIT) and radiation-based sterile insect technique (SIT) can be used for population suppression of Aedes aegypti. Our main objective was to evaluate whether open-field mass-releases of wAlbB-infected Ae. aegypti males, as pa...
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ftdoajarticles:oai:doaj.org/article:7f44045e69984bbf9cb093e47991647a 2023-05-15T15:17:29+02:00 Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico Abdiel Martín-Park Azael Che-Mendoza Yamili Contreras-Perera Silvia Pérez-Carrillo Henry Puerta-Guardo Josué Villegas-Chim Guillermo Guillermo-May Anuar Medina-Barreiro Hugo Delfín-González Rosa Méndez-Vales Santos Vázquez-Narvaez Jorge Palacio-Vargas Fabián Correa-Morales Guadalupe Ayora-Talavera Norma Pavía-Ruz Xiao Liang Ping Fu Dongjing Zhang Xiaohua Wang María Eugenia Toledo-Romaní Zhiyong Xi Gonzalo Vázquez-Prokopec Pablo Manrique-Saide 2022-04-01T00:00:00Z https://doaj.org/article/7f44045e69984bbf9cb093e47991647a EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041844/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/7f44045e69984bbf9cb093e47991647a PLoS Neglected Tropical Diseases, Vol 16, Iss 4 (2022) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles 2022-12-30T23:59:32Z Background The combination of Wolbachia-based incompatible insect technique (IIT) and radiation-based sterile insect technique (SIT) can be used for population suppression of Aedes aegypti. Our main objective was to evaluate whether open-field mass-releases of wAlbB-infected Ae. aegypti males, as part of an Integrated Vector Management (IVM) plan led by the Mexican Ministry of Health, could suppress natural populations of Ae. aegypti in urbanized settings in south Mexico. Methodology/Principal findings We implemented a controlled before-and-after quasi-experimental study in two suburban localities of Yucatan (Mexico): San Pedro Chimay (SPC), which received IIT-SIT, and San Antonio Tahdzibichén used as control. Release of wAlbB Ae. aegypti males at SPC extended for 6 months (July-December 2019), covering the period of higher Ae. aegypti abundance. Entomological indicators included egg hatching rates and outdoor/indoor adult females collected at the release and control sites. Approximately 1,270,000 lab-produced wAlbB-infected Ae. aegypti males were released in the 50-ha treatment area (2,000 wAlbB Ae. aegypti males per hectare twice a week in two different release days, totaling 200,000 male mosquitoes per week). The efficacy of IIT-SIT in suppressing indoor female Ae. aegypti density (quantified from a generalized linear mixed model showing a statistically significant reduction in treatment versus control areas) was 90.9% a month after initiation of the suppression phase, 47.7% two months after (when number of released males was reduced in 50% to match local abundance), 61.4% four months after (when initial number of released males was re-established), 88.4% five months after and 89.4% at six months after the initiation of the suppression phase. A proportional, but lower, reduction in outdoor female Ae. aegypti was also quantified (range, 50.0–75.2% suppression). Conclusions/Significance Our study, the first open-field pilot implementation of Wolbachia IIT-SIT in Mexico and Latin-America, confirms that ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Abdiel Martín-Park Azael Che-Mendoza Yamili Contreras-Perera Silvia Pérez-Carrillo Henry Puerta-Guardo Josué Villegas-Chim Guillermo Guillermo-May Anuar Medina-Barreiro Hugo Delfín-González Rosa Méndez-Vales Santos Vázquez-Narvaez Jorge Palacio-Vargas Fabián Correa-Morales Guadalupe Ayora-Talavera Norma Pavía-Ruz Xiao Liang Ping Fu Dongjing Zhang Xiaohua Wang María Eugenia Toledo-Romaní Zhiyong Xi Gonzalo Vázquez-Prokopec Pablo Manrique-Saide Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background The combination of Wolbachia-based incompatible insect technique (IIT) and radiation-based sterile insect technique (SIT) can be used for population suppression of Aedes aegypti. Our main objective was to evaluate whether open-field mass-releases of wAlbB-infected Ae. aegypti males, as part of an Integrated Vector Management (IVM) plan led by the Mexican Ministry of Health, could suppress natural populations of Ae. aegypti in urbanized settings in south Mexico. Methodology/Principal findings We implemented a controlled before-and-after quasi-experimental study in two suburban localities of Yucatan (Mexico): San Pedro Chimay (SPC), which received IIT-SIT, and San Antonio Tahdzibichén used as control. Release of wAlbB Ae. aegypti males at SPC extended for 6 months (July-December 2019), covering the period of higher Ae. aegypti abundance. Entomological indicators included egg hatching rates and outdoor/indoor adult females collected at the release and control sites. Approximately 1,270,000 lab-produced wAlbB-infected Ae. aegypti males were released in the 50-ha treatment area (2,000 wAlbB Ae. aegypti males per hectare twice a week in two different release days, totaling 200,000 male mosquitoes per week). The efficacy of IIT-SIT in suppressing indoor female Ae. aegypti density (quantified from a generalized linear mixed model showing a statistically significant reduction in treatment versus control areas) was 90.9% a month after initiation of the suppression phase, 47.7% two months after (when number of released males was reduced in 50% to match local abundance), 61.4% four months after (when initial number of released males was re-established), 88.4% five months after and 89.4% at six months after the initiation of the suppression phase. A proportional, but lower, reduction in outdoor female Ae. aegypti was also quantified (range, 50.0–75.2% suppression). Conclusions/Significance Our study, the first open-field pilot implementation of Wolbachia IIT-SIT in Mexico and Latin-America, confirms that ... |
format |
Article in Journal/Newspaper |
author |
Abdiel Martín-Park Azael Che-Mendoza Yamili Contreras-Perera Silvia Pérez-Carrillo Henry Puerta-Guardo Josué Villegas-Chim Guillermo Guillermo-May Anuar Medina-Barreiro Hugo Delfín-González Rosa Méndez-Vales Santos Vázquez-Narvaez Jorge Palacio-Vargas Fabián Correa-Morales Guadalupe Ayora-Talavera Norma Pavía-Ruz Xiao Liang Ping Fu Dongjing Zhang Xiaohua Wang María Eugenia Toledo-Romaní Zhiyong Xi Gonzalo Vázquez-Prokopec Pablo Manrique-Saide |
author_facet |
Abdiel Martín-Park Azael Che-Mendoza Yamili Contreras-Perera Silvia Pérez-Carrillo Henry Puerta-Guardo Josué Villegas-Chim Guillermo Guillermo-May Anuar Medina-Barreiro Hugo Delfín-González Rosa Méndez-Vales Santos Vázquez-Narvaez Jorge Palacio-Vargas Fabián Correa-Morales Guadalupe Ayora-Talavera Norma Pavía-Ruz Xiao Liang Ping Fu Dongjing Zhang Xiaohua Wang María Eugenia Toledo-Romaní Zhiyong Xi Gonzalo Vázquez-Prokopec Pablo Manrique-Saide |
author_sort |
Abdiel Martín-Park |
title |
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
title_short |
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
title_full |
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
title_fullStr |
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
title_full_unstemmed |
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico |
title_sort |
pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated aedes aegypti control in mexico |
publisher |
Public Library of Science (PLoS) |
publishDate |
2022 |
url |
https://doaj.org/article/7f44045e69984bbf9cb093e47991647a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 16, Iss 4 (2022) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041844/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/7f44045e69984bbf9cb093e47991647a |
_version_ |
1766347727674802176 |