Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil
Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute br...
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ftdoajarticles:oai:doaj.org/article:7f20fbf1b53b426d8e4015f6be9c790e 2023-05-15T15:01:30+02:00 Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil Karine Mattos Luana Carbonera Rodrigues Kelly Mari Pires de Oliveira Pedro Fernando Diniz Luiza Inahê Marques Adriana Almeida Araujo Marilene Rodrigues Chang https://doi.org/10.1590/0037-8682-0163-2017 https://doaj.org/article/7f20fbf1b53b426d8e4015f6be9c790e EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000600843&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0163-2017 https://doaj.org/article/7f20fbf1b53b426d8e4015f6be9c790e Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 6, Pp 843-847 Candidiasis Candidemia Epidemiology Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0163-2017 2022-12-30T21:27:57Z Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute broth microdilution and genomic differentiation using PCR. RESULTS Of 221 Candida isolates, 50.2% were obtained from intensive care unit patients; 71.5% were recovered from urine and 9.1% from bloodstream samples. Candida parapsilosis sensu stricto was the most common candidemia agent. CONCLUSIONS We observed variations in Candida species distribution in hospitals in the same geographic region and documented the emergence of non-C. albicans species resistant to azoles. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 50 6 843 847 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Candidiasis Candidemia Epidemiology Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Candidiasis Candidemia Epidemiology Arctic medicine. Tropical medicine RC955-962 Karine Mattos Luana Carbonera Rodrigues Kelly Mari Pires de Oliveira Pedro Fernando Diniz Luiza Inahê Marques Adriana Almeida Araujo Marilene Rodrigues Chang Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
topic_facet |
Candidiasis Candidemia Epidemiology Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute broth microdilution and genomic differentiation using PCR. RESULTS Of 221 Candida isolates, 50.2% were obtained from intensive care unit patients; 71.5% were recovered from urine and 9.1% from bloodstream samples. Candida parapsilosis sensu stricto was the most common candidemia agent. CONCLUSIONS We observed variations in Candida species distribution in hospitals in the same geographic region and documented the emergence of non-C. albicans species resistant to azoles. |
format |
Article in Journal/Newspaper |
author |
Karine Mattos Luana Carbonera Rodrigues Kelly Mari Pires de Oliveira Pedro Fernando Diniz Luiza Inahê Marques Adriana Almeida Araujo Marilene Rodrigues Chang |
author_facet |
Karine Mattos Luana Carbonera Rodrigues Kelly Mari Pires de Oliveira Pedro Fernando Diniz Luiza Inahê Marques Adriana Almeida Araujo Marilene Rodrigues Chang |
author_sort |
Karine Mattos |
title |
Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
title_short |
Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
title_full |
Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
title_fullStr |
Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
title_full_unstemmed |
Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil |
title_sort |
variability in the clinical distributions of candida species and the emergence of azole-resistant non-candida albicans species in public hospitals in the midwest region of brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
url |
https://doi.org/10.1590/0037-8682-0163-2017 https://doaj.org/article/7f20fbf1b53b426d8e4015f6be9c790e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 6, Pp 843-847 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000600843&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0163-2017 https://doaj.org/article/7f20fbf1b53b426d8e4015f6be9c790e |
op_doi |
https://doi.org/10.1590/0037-8682-0163-2017 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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50 |
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847 |
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