Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model.
The substantial morbidity and mortality associated with recent cholera outbreaks in Haiti and Zimbabwe, as well as with cholera endemicity in countries throughout Asia and Africa, make a compelling case for supplementary cholera control measures in addition to existing interventions. Clinical trials...
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ftdoajarticles:oai:doaj.org/article:7da7ea785401440297ef00695b4a3ca8 2023-05-15T15:16:44+02:00 Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. Shantanu K Kar Binod Sah Bikash Patnaik Yang Hee Kim Anna S Kerketta Sunheang Shin Shyam Bandhu Rath Mohammad Ali Vittal Mogasale Hemant K Khuntia Anuj Bhattachan Young Ae You Mahesh K Puri Anna Lena Lopez Brian Maskery Gopinath B Nair John D Clemens Thomas F Wierzba 2014-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002629 https://doaj.org/article/7da7ea785401440297ef00695b4a3ca8 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3916257?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002629 https://doaj.org/article/7da7ea785401440297ef00695b4a3ca8 PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2629 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002629 2022-12-31T16:22:43Z The substantial morbidity and mortality associated with recent cholera outbreaks in Haiti and Zimbabwe, as well as with cholera endemicity in countries throughout Asia and Africa, make a compelling case for supplementary cholera control measures in addition to existing interventions. Clinical trials conducted in Kolkata, India, have led to World Health Organization (WHO)-prequalification of Shanchol, an oral cholera vaccine (OCV) with a demonstrated 65% efficacy at 5 years post-vaccination. However, before this vaccine is widely used in endemic areas or in areas at risk of outbreaks, as recommended by the WHO, policymakers will require empirical evidence on its implementation and delivery costs in public health programs. The objective of the present report is to describe the organization, vaccine coverage, and delivery costs of mass vaccination with a new, less expensive OCV (Shanchol) using existing public health infrastructure in Odisha, India, as a model.All healthy, non-pregnant residents aged 1 year and above residing in selected villages of the Satyabadi block (Puri district, Odisha, India) were invited to participate in a mass vaccination campaign using two doses of OCV. Prior to the campaign, a de jure census, micro-planning for vaccination and social mobilization activities were implemented. Vaccine coverage for each dose was ascertained as a percentage of the censused population. The direct vaccine delivery costs were estimated by reviewing project expenditure records and by interviewing key personnel.The mass vaccination was conducted during May and June, 2011, in two phases. In each phase, two vaccine doses were given 14 days apart. Sixty-two vaccination booths, staffed by 395 health workers/volunteers, were established in the community. For the censused population, 31,552 persons (61% of the target population) received the first dose and 23,751 (46%) of these completed their second dose, with a drop-out rate of 25% between the two doses. Higher coverage was observed among females and among 6-17 ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 2 e2629 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Shantanu K Kar Binod Sah Bikash Patnaik Yang Hee Kim Anna S Kerketta Sunheang Shin Shyam Bandhu Rath Mohammad Ali Vittal Mogasale Hemant K Khuntia Anuj Bhattachan Young Ae You Mahesh K Puri Anna Lena Lopez Brian Maskery Gopinath B Nair John D Clemens Thomas F Wierzba Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The substantial morbidity and mortality associated with recent cholera outbreaks in Haiti and Zimbabwe, as well as with cholera endemicity in countries throughout Asia and Africa, make a compelling case for supplementary cholera control measures in addition to existing interventions. Clinical trials conducted in Kolkata, India, have led to World Health Organization (WHO)-prequalification of Shanchol, an oral cholera vaccine (OCV) with a demonstrated 65% efficacy at 5 years post-vaccination. However, before this vaccine is widely used in endemic areas or in areas at risk of outbreaks, as recommended by the WHO, policymakers will require empirical evidence on its implementation and delivery costs in public health programs. The objective of the present report is to describe the organization, vaccine coverage, and delivery costs of mass vaccination with a new, less expensive OCV (Shanchol) using existing public health infrastructure in Odisha, India, as a model.All healthy, non-pregnant residents aged 1 year and above residing in selected villages of the Satyabadi block (Puri district, Odisha, India) were invited to participate in a mass vaccination campaign using two doses of OCV. Prior to the campaign, a de jure census, micro-planning for vaccination and social mobilization activities were implemented. Vaccine coverage for each dose was ascertained as a percentage of the censused population. The direct vaccine delivery costs were estimated by reviewing project expenditure records and by interviewing key personnel.The mass vaccination was conducted during May and June, 2011, in two phases. In each phase, two vaccine doses were given 14 days apart. Sixty-two vaccination booths, staffed by 395 health workers/volunteers, were established in the community. For the censused population, 31,552 persons (61% of the target population) received the first dose and 23,751 (46%) of these completed their second dose, with a drop-out rate of 25% between the two doses. Higher coverage was observed among females and among 6-17 ... |
format |
Article in Journal/Newspaper |
author |
Shantanu K Kar Binod Sah Bikash Patnaik Yang Hee Kim Anna S Kerketta Sunheang Shin Shyam Bandhu Rath Mohammad Ali Vittal Mogasale Hemant K Khuntia Anuj Bhattachan Young Ae You Mahesh K Puri Anna Lena Lopez Brian Maskery Gopinath B Nair John D Clemens Thomas F Wierzba |
author_facet |
Shantanu K Kar Binod Sah Bikash Patnaik Yang Hee Kim Anna S Kerketta Sunheang Shin Shyam Bandhu Rath Mohammad Ali Vittal Mogasale Hemant K Khuntia Anuj Bhattachan Young Ae You Mahesh K Puri Anna Lena Lopez Brian Maskery Gopinath B Nair John D Clemens Thomas F Wierzba |
author_sort |
Shantanu K Kar |
title |
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
title_short |
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
title_full |
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
title_fullStr |
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
title_full_unstemmed |
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha model. |
title_sort |
mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in india: the odisha model. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0002629 https://doaj.org/article/7da7ea785401440297ef00695b4a3ca8 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2629 (2014) |
op_relation |
http://europepmc.org/articles/PMC3916257?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002629 https://doaj.org/article/7da7ea785401440297ef00695b4a3ca8 |
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https://doi.org/10.1371/journal.pntd.0002629 |
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PLoS Neglected Tropical Diseases |
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8 |
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2 |
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e2629 |
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