Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal.
Nepal, Bangladesh, and India signed a Memorandum of Understanding (MoU) in 2005 to eliminate visceral leishmaniasis (VL) as a public health problem from the Indian subcontinent by 2015. By 2021, the number of reported VL cases in these countries had declined by over 95% compared to 2007. This dramat...
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ftdoajarticles:oai:doaj.org/article:7d18c0ab66284e7290aebcd3d9e5e8c6 2024-01-28T10:04:08+01:00 Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. Anand Ballabh Joshi Megha Raj Banjara Sachi Chuke Axel Kroeger Saurabh Jain Abraham Aseffa John C Reeder 2023-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0011714 https://doaj.org/article/7d18c0ab66284e7290aebcd3d9e5e8c6 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0011714 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011714 https://doaj.org/article/7d18c0ab66284e7290aebcd3d9e5e8c6 PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011714 (2023) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.1371/journal.pntd.0011714 2023-12-31T01:49:22Z Nepal, Bangladesh, and India signed a Memorandum of Understanding (MoU) in 2005 to eliminate visceral leishmaniasis (VL) as a public health problem from the Indian subcontinent by 2015. By 2021, the number of reported VL cases in these countries had declined by over 95% compared to 2007. This dramatic success was achieved through an elimination programme that implemented early case detection and effective treatment, vector control, disease surveillance, community participation, and operational research that underpinned these strategies. The experience offered an opportunity to assess the contribution of implementation research (IR) to VL elimination in Nepal. Desk review and a stakeholder workshop was conducted to analyse the relationship between key research outputs, major strategic decisions in the national VL elimination programme, and annual number of reported new cases over time between 2005 and 2023. The results indicated that the key decisions across the strategic elements, throughout the course of the elimination programme (such as on the most appropriate tools for diganostics and treatment, and on best strategies for case finding and vector management), were IR informed. IR itself responded dynamically to changes that resulted from interventions, addressing new questions that emerged from the field. Close collaboration between researchers, programme managers, and implementers in priority setting, design, conduct, and review of studies facilitated uptake of evidence into policy and programmatic activities. VL case numbers in Nepal are now reduced by 90% compared to 2005. Although direct attribution of disease decline to research outputs is difficult to establish, the Nepal experience demonstrates that IR can be a critical enabler for disease elimination. The lessons can potentially inform IR strategies in other countries with diseases targeted for elimination. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Indian PLOS Neglected Tropical Diseases 17 11 e0011714 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Anand Ballabh Joshi Megha Raj Banjara Sachi Chuke Axel Kroeger Saurabh Jain Abraham Aseffa John C Reeder Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Nepal, Bangladesh, and India signed a Memorandum of Understanding (MoU) in 2005 to eliminate visceral leishmaniasis (VL) as a public health problem from the Indian subcontinent by 2015. By 2021, the number of reported VL cases in these countries had declined by over 95% compared to 2007. This dramatic success was achieved through an elimination programme that implemented early case detection and effective treatment, vector control, disease surveillance, community participation, and operational research that underpinned these strategies. The experience offered an opportunity to assess the contribution of implementation research (IR) to VL elimination in Nepal. Desk review and a stakeholder workshop was conducted to analyse the relationship between key research outputs, major strategic decisions in the national VL elimination programme, and annual number of reported new cases over time between 2005 and 2023. The results indicated that the key decisions across the strategic elements, throughout the course of the elimination programme (such as on the most appropriate tools for diganostics and treatment, and on best strategies for case finding and vector management), were IR informed. IR itself responded dynamically to changes that resulted from interventions, addressing new questions that emerged from the field. Close collaboration between researchers, programme managers, and implementers in priority setting, design, conduct, and review of studies facilitated uptake of evidence into policy and programmatic activities. VL case numbers in Nepal are now reduced by 90% compared to 2005. Although direct attribution of disease decline to research outputs is difficult to establish, the Nepal experience demonstrates that IR can be a critical enabler for disease elimination. The lessons can potentially inform IR strategies in other countries with diseases targeted for elimination. |
format |
Article in Journal/Newspaper |
author |
Anand Ballabh Joshi Megha Raj Banjara Sachi Chuke Axel Kroeger Saurabh Jain Abraham Aseffa John C Reeder |
author_facet |
Anand Ballabh Joshi Megha Raj Banjara Sachi Chuke Axel Kroeger Saurabh Jain Abraham Aseffa John C Reeder |
author_sort |
Anand Ballabh Joshi |
title |
Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
title_short |
Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
title_full |
Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
title_fullStr |
Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
title_full_unstemmed |
Assessment of the impact of implementation research on the Visceral Leishmaniasis (VL) elimination efforts in Nepal. |
title_sort |
assessment of the impact of implementation research on the visceral leishmaniasis (vl) elimination efforts in nepal. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doi.org/10.1371/journal.pntd.0011714 https://doaj.org/article/7d18c0ab66284e7290aebcd3d9e5e8c6 |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011714 (2023) |
op_relation |
https://doi.org/10.1371/journal.pntd.0011714 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011714 https://doaj.org/article/7d18c0ab66284e7290aebcd3d9e5e8c6 |
op_doi |
https://doi.org/10.1371/journal.pntd.0011714 |
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PLOS Neglected Tropical Diseases |
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17 |
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11 |
container_start_page |
e0011714 |
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